Estring and Headache - a phase IV clinical study of FDA data

Summary:

We study 4,497 people who have side effects when taking Estring. Headache is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Synthroid and have Vulvovaginal dryness.

The phase IV clinical study analyzes which people take Estring and have Headache. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 27, 2023

4,497 people reported to have side effects when taking Estring.
Among them, 178 people (3.96%) have Headache.

What is Estring?

Estring has active ingredients of estradiol. Currently, eHealthMe is studying from 4,988 Estring users.

What is Headache?

Headache (pain in head) is found to be associated with 5,276 drugs and 5,646 conditions by eHealthMe. Currently, we are studying 714,741 people who have Headache.

Number of Estring and Headache reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Estring and have Headache?

Check whether Headache is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Estring side effects by duration, gender and age:

Estring side effects (4,988 reports)

Headache treatments and more:

Headache (714,741 reports)

Common drugs associated with Headache:

All the drugs that are associated with Headache:

Headache (5,276 drugs)

Common conditions associated with Headache:

Multiple sclerosis: 41,461 reports
Rheumatoid arthritis: 40,932 reports
High blood pressure: 24,649 reports
Primary pulmonary hypertension: 21,717 reports
Psoriasis: 21,398 reports

All the conditions that are associated with Headache:

Headache (5,646 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Estring) and Estring (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.