Etodolac and Joint stiffness - a phase IV clinical study of FDA data


Joint stiffness is found among people who take Etodolac, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Etodolac and have Joint stiffness. It is created by eHealthMe based on reports of 8,282 people who have side effects when taking Etodolac from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Aug, 09, 2022

8,282 people reported to have side effects when taking Etodolac.
Among them, 45 people (0.54%) have Joint stiffness.

What is Etodolac?

Etodolac has active ingredients of etodolac. It is often used in arthritis. eHealthMe is studying from 8,419 Etodolac users for its effectiveness, alternative drugs and more.

What is Joint stiffness?

Joint stiffness is found to be associated with 1,804 drugs and 1,265 conditions by eHealthMe.

Number of Etodolac and Joint stiffness reports submitted per year:

Could Etodolac cause Joint stiffness?

Gender of people who have Joint stiffness when taking Etodolac *:

  • female: 86.67 %
  • male: 13.33 %

Age of people who have Joint stiffness when taking Etodolac *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.45 %
  • 40-49: 12.9 %
  • 50-59: 29.03 %
  • 60+: 51.61 %

Common drugs people take besides Etodolac *:

  1. Ampyra: 13 people, 28.89%
  2. Restasis: 8 people, 17.78%
  3. Humira: 8 people, 17.78%
  4. Ambien: 8 people, 17.78%
  5. Vitamin D3: 8 people, 17.78%
  6. Vitamin B12: 8 people, 17.78%
  7. Tysabri: 7 people, 15.56%
  8. Myrbetriq: 7 people, 15.56%
  9. Januvia: 7 people, 15.56%
  10. Fosamax: 7 people, 15.56%

Common side effects people have besides Joint stiffness *:

  1. Joint Pain: 25 people, 55.56%
  2. Depression: 16 people, 35.56%
  3. Gait Disturbance: 14 people, 31.11%
  4. Back Pain: 13 people, 28.89%
  5. Muscle Spasms (muscle contraction): 12 people, 26.67%
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 12 people, 26.67%
  7. Fatigue (feeling of tiredness): 12 people, 26.67%
  8. Headache (pain in head): 12 people, 26.67%
  9. Hypoaesthesia (reduced sense of touch or sensation): 12 people, 26.67%
  10. Balance Disorder: 12 people, 26.67%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 33.33%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 13 people, 28.89%
  3. Gait Disturbance: 9 people, 20.00%
  4. Urethritis Noninfective (inflammation of the urethra - non infective): 7 people, 15.56%
  5. Bladder Disorder: 7 people, 15.56%
  6. Blood Glucose Abnormal: 7 people, 15.56%
  7. Cough: 7 people, 15.56%
  8. High Blood Cholesterol: 6 people, 13.33%
  9. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 13.33%
  10. Gastric Disorder (disease of stomach): 5 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Etodolac and have Joint stiffness?

Check whether Joint stiffness is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of Etodolac:

Joint stiffness treatments and more:

COVID vaccines that are related to Joint stiffness:

How severe was Joint stiffness and when was it recovered:

Expand to all the drugs that have ingredients of etodolac:

Common drugs associated with Joint stiffness:

All the drugs that are associated with Joint stiffness:

Common conditions associated with Joint stiffness:

All the conditions that are associated with Joint stiffness:

How the study uses the data?

The study uses data from the FDA. It is based on etodolac (the active ingredients of Etodolac) and Etodolac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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