Euthyrox and Spinal compression fracture - a phase IV clinical study of FDA data


Spinal compression fracture is found among people who take Euthyrox, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Euthyrox and have Spinal compression fracture. It is created by eHealthMe based on reports of 6,314 people who have side effects when taking Euthyrox from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 28, 2023

6,314 people reported to have side effects when taking Euthyrox.
Among them, 6 people (0.1%) have Spinal compression fracture.

What is Euthyrox?

Euthyrox has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 6,418 Euthyrox users for its effectiveness, alternative drugs and more.

What is Spinal compression fracture?

Spinal compression fracture (fracture due to spinal compression on bone) is found to be associated with 1,695 drugs and 818 conditions by eHealthMe.

Number of Euthyrox and Spinal compression fracture reports submitted per year:

Could Euthyrox cause Spinal compression fracture?

Time on Euthyrox when people have Spinal compression fracture *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Spinal compression fracture when taking Euthyrox *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Spinal compression fracture when taking Euthyrox *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Euthyrox *:

  1. Vitamin D: 4 people, 66.67%
  2. Vitamin B12: 4 people, 66.67%
  3. Prednisone: 4 people, 66.67%
  4. Plaquenil: 4 people, 66.67%
  5. Methotrexate: 4 people, 66.67%
  6. Leflunomide: 4 people, 66.67%
  7. Folic Acid: 4 people, 66.67%
  8. Biotin: 4 people, 66.67%
  9. Prolia: 1 person, 16.67%
  10. Cytomel: 1 person, 16.67%

Common side effects people have besides Spinal compression fracture *:

  1. Rashes (redness): 4 people, 66.67%
  2. Insomnia (sleeplessness): 4 people, 66.67%
  3. Back Disorder: 4 people, 66.67%
  4. Scoliosis (a medical condition in which a person's spine is curved from side to side): 1 person, 16.67%
  5. Overdose: 1 person, 16.67%
  6. Osteoporosis (bones weak and more likely to break): 1 person, 16.67%
  7. Musculoskeletal Discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 1 person, 16.67%
  8. Bone Pain: 1 person, 16.67%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 66.67%
  2. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Euthyrox and have Spinal compression fracture?

Check whether Spinal compression fracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Spinal compression fracture and when was it recovered:

Expand to all the drugs that have ingredients of levothyroxine sodium:

Alternative drugs to, pros and cons of Euthyrox:

Common Euthyrox side effects:

Browse all side effects of Euthyrox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Spinal compression fracture treatments and more:

COVID vaccines that are related to Spinal compression fracture:

Common drugs associated with Spinal compression fracture:

All the drugs that are associated with Spinal compression fracture:

Common conditions associated with Spinal compression fracture:

All the conditions that are associated with Spinal compression fracture:

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Euthyrox) and Euthyrox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: