Euthyrox and Z-e syndrome - a phase IV clinical study of FDA data

Summary:

Z-e syndrome is reported only by a few people who take Euthyrox.

The phase IV clinical study analyzes which people take Euthyrox and have Z-e syndrome. It is created by eHealthMe based on reports of 7,724 people who have side effects while taking Euthyrox from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 17, 2023

7,724 people reported to have side effects when taking Euthyrox.
Among them, 1 person (0.01%) has Z-e syndrome.

What is Euthyrox?

Euthyrox has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 6,426 Euthyrox users for its effectiveness, alternative drugs and more.

What is Z-e syndrome?

Z-e syndrome (increased production of the hormone gastrin from a small tumour of pancreas) is found to be associated with 153 drugs and 172 conditions by eHealthMe.

Number of Euthyrox and Z-e syndrome reports submitted per year:

Gender of people who have Z-e syndrome when taking Euthyrox *:

female: 100 %
male: 0.0 %

Age of people who have Z-e syndrome when taking Euthyrox *:

Common side effects people have besides Z-e syndrome *:

Oesophageal Ulcer (ulcer of oesophagus): 1 person, 100.00%
Neuroendocrine Tumor: 1 person, 100.00%
Mucosal Inflammation (infection of mucous membrane): 1 person, 100.00%
Melaena (the passage of black, tarry stools): 1 person, 100.00%
Malignant Neoplasm Progression (cancer tumour came back): 1 person, 100.00%
Gastric Ulcer (stomach ulcer): 1 person, 100.00%
Fatigue (feeling of tiredness): 1 person, 100.00%
Electrolyte Imbalance: 1 person, 100.00%
Blood Gastrin Increased: 1 person, 100.00%
Anaemia (lack of blood): 1 person, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Euthyrox and have Z-e syndrome?

Check whether Z-e syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Z-e syndrome and when was it recovered:

Z-e syndrome in Euthyrox

Expand to all the drugs that have ingredients of levothyroxine sodium:

Z-e syndrome and drugs with ingredients of levothyroxine sodium (4 reports)

Alternative drugs to, pros and cons of Euthyrox:

Euthyrox (6,426 reports)

Common Euthyrox side effects:

Fatigue (feeling of tiredness): 966 reports
Dizziness: 786 reports
Weakness: 681 reports
Headache (pain in head): 604 reports
Diarrhea: 528 reports
Breathing difficulty: 436 reports
Insomnia (sleeplessness): 421 reports
High blood pressure: 384 reports
Stress and anxiety: 382 reports

Browse all side effects of Euthyrox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Z-e syndrome treatments and more:

Z-e syndrome (1,123 reports)

COVID vaccines that are related to Z-e syndrome:

All the drugs that are associated with Z-e syndrome:

Z-e syndrome (153 drugs)

All the conditions that are associated with Z-e syndrome:

Z-e syndrome (172 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Euthyrox) and Euthyrox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.