Exforge and Musculoskeletal chest pain - a phase IV clinical study of FDA data


Musculoskeletal chest pain is found among people who take Exforge, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Exforge and have Musculoskeletal chest pain. It is created by eHealthMe based on reports of 12,119 people who have side effects when taking Exforge from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

12,119 people reported to have side effects when taking Exforge.
Among them, 14 people (0.12%) have Musculoskeletal chest pain.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 12,516 Exforge users for its effectiveness, alternative drugs and more.

What is Musculoskeletal chest pain?

Musculoskeletal chest pain (pain in chest muscle or nerve or bones) is found to be associated with 1,836 drugs and 1,014 conditions by eHealthMe.

Number of Exforge and Musculoskeletal chest pain reports submitted per year:

Could Exforge cause Musculoskeletal chest pain?

Gender of people who have Musculoskeletal chest pain when taking Exforge *:

  • female: 71.43 %
  • male: 28.57 %

Age of people who have Musculoskeletal chest pain when taking Exforge *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 18.18 %
  • 60+: 81.82 %

Common drugs people take besides Exforge *:

  1. Omega 3: 2 people, 14.29%
  2. Faslodex: 2 people, 14.29%
  3. Aspirin: 2 people, 14.29%
  4. Hydrochlorothiazide: 2 people, 14.29%
  5. Coumadin: 2 people, 14.29%
  6. Gilenya: 2 people, 14.29%
  7. Diovan: 2 people, 14.29%
  8. Kisqali: 2 people, 14.29%
  9. Metoprolol Tartrate: 2 people, 14.29%
  10. Humira: 1 person, 7.14%

Common side effects people have besides Musculoskeletal chest pain *:

  1. Back Pain: 4 people, 28.57%
  2. Diarrhea: 4 people, 28.57%
  3. Fatigue (feeling of tiredness): 3 people, 21.43%
  4. High Blood Cholesterol: 3 people, 21.43%
  5. Pain: 3 people, 21.43%
  6. Dehydration (dryness resulting from the removal of water): 3 people, 21.43%
  7. Hypotension (abnormally low blood pressure): 3 people, 21.43%
  8. Nausea (feeling of having an urge to vomit): 3 people, 21.43%
  9. Fall: 3 people, 21.43%
  10. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 2 people, 14.29%

Common conditions people have *:

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 14.29%
  2. Diabetes: 2 people, 14.29%
  3. Breast Cancer: 2 people, 14.29%
  4. Type 2 Diabetes: 1 person, 7.14%
  5. Thyroid Diseases: 1 person, 7.14%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
  7. Pain: 1 person, 7.14%
  8. Oedema (fluid collection in tissue): 1 person, 7.14%
  9. Neuroendocrine Tumor: 1 person, 7.14%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and have Musculoskeletal chest pain?

Check whether Musculoskeletal chest pain is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Musculoskeletal chest pain and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate; valsartan:

Alternative drugs to, pros and cons of Exforge:

Common Exforge side effects:

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Musculoskeletal chest pain treatments and more:

COVID vaccines that are related to Musculoskeletal chest pain:

Common drugs associated with Musculoskeletal chest pain:

All the drugs that are associated with Musculoskeletal chest pain:

Common conditions associated with Musculoskeletal chest pain:

All the conditions that are associated with Musculoskeletal chest pain:

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan (the active ingredients of Exforge) and Exforge (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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