Exidine and Drug toxicity - a phase IV clinical study of FDA data


We study 15,490 people who have side effects when taking Exidine. Drug toxicity is found, especially among people who are male, 60+ old, also take Vancomycin and have Multiple myeloma.

The phase IV clinical study analyzes which people take Exidine and have Drug toxicity. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

15,490 people reported to have side effects when taking Exidine.
Among them, 25 people (0.16%) have Drug toxicity.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. Currently, eHealthMe is studying from 15,543 Exidine users.

What is Drug toxicity?

Drug toxicity is found to be associated with 1,866 drugs and 1,377 conditions by eHealthMe. Currently, we are studying 20,258 people who have Drug toxicity.

Number of Exidine and Drug toxicity reports submitted per year:

Could Exidine cause Drug toxicity?

Gender of people who have Drug toxicity when taking Exidine *:

  • female: 20 %
  • male: 80 %

Age of people who have Drug toxicity when taking Exidine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 10.53 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 31.58 %
  • 50-59: 15.79 %
  • 60+: 42.11 %

Common drugs people take besides Exidine *:

  1. Vancomycin: 12 people, 48.00%
  2. Aredia: 11 people, 44.00%
  3. Zometa: 10 people, 40.00%
  4. Protonix: 10 people, 40.00%
  5. Dexamethasone: 9 people, 36.00%
  6. Septra Ds: 9 people, 36.00%
  7. Thalidomide: 9 people, 36.00%
  8. Coumadin: 8 people, 32.00%
  9. Ondansetron: 8 people, 32.00%
  10. Prednisone: 8 people, 32.00%

Common side effects people have besides Drug toxicity *:

  1. Infection: 10 people, 40.00%
  2. Stress And Anxiety: 10 people, 40.00%
  3. High Blood Pressure: 10 people, 40.00%
  4. Back Pain: 10 people, 40.00%
  5. Pain: 10 people, 40.00%
  6. Cough: 10 people, 40.00%
  7. Headache (pain in head): 9 people, 36.00%
  8. Emotional Distress: 9 people, 36.00%
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 36.00%
  10. Disease Recurrence: 9 people, 36.00%

Common conditions people have *:

  1. Multiple Myeloma (cancer of the plasma cells): 9 people, 36.00%
  2. Prostate Cancer: 1 person, 4.00%
  3. Ovarian Cancer (cancer of ovary): 1 person, 4.00%
  4. Depression: 1 person, 4.00%
  5. Breast Cancer: 1 person, 4.00%
  6. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Exidine and have Drug toxicity?

Check whether Drug toxicity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

  • Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .

Related studies

Exidine side effects by duration, gender and age:

Drug toxicity treatments and more:

Common drugs associated with Drug toxicity:

All the drugs that are associated with Drug toxicity:

Common conditions associated with Drug toxicity:

All the conditions that are associated with Drug toxicity:

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Exidine) and Exidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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