Fentanyl and Application site scab - a phase IV clinical study of FDA data


Application site scab is found among people who take Fentanyl, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Fentanyl and have Application site scab. It is created by eHealthMe based on reports of 67,064 people who have side effects when taking Fentanyl from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 07, 2022

67,064 people reported to have side effects when taking Fentanyl.
Among them, 25 people (0.04%) have Application site scab.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 67,692 Fentanyl users for its effectiveness, alternative drugs and more.

What is Application site scab?

Application site scab (hard coating on the skin formed at application site) is found to be associated with 372 drugs and 258 conditions by eHealthMe.

Number of Fentanyl and Application site scab reports submitted per year:

Could Fentanyl cause Application site scab?

Time on Fentanyl when people have Application site scab *:

  • < 1 month: 75 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Application site scab when taking Fentanyl *:

  • female: 68 %
  • male: 32 %

Age of people who have Application site scab when taking Fentanyl *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.56 %
  • 30-39: 0.0 %
  • 40-49: 22.22 %
  • 50-59: 16.67 %
  • 60+: 55.56 %

Common drugs people take besides Fentanyl *:

  1. Fentanyl Transdermal System: 7 people, 28.00%
  2. Klonopin: 4 people, 16.00%
  3. Vicodin: 3 people, 12.00%
  4. Synthroid: 3 people, 12.00%
  5. Duragesic-100: 3 people, 12.00%
  6. Colace: 2 people, 8.00%
  7. Flomax: 2 people, 8.00%
  8. Valium: 2 people, 8.00%
  9. Nexium: 2 people, 8.00%
  10. Norco: 2 people, 8.00%

Common side effects people have besides Application site scab *:

  1. Application Site Erythema (redness of the skin at application site): 10 people, 40.00%
  2. Application Site Burn: 6 people, 24.00%
  3. Application Site Irritation: 5 people, 20.00%
  4. Application Site Pruritus (application site severe itching of the skin): 5 people, 20.00%
  5. Application Site Erosion: 4 people, 16.00%
  6. Application Site Pain: 4 people, 16.00%
  7. Application Site Reaction: 4 people, 16.00%
  8. Wound: 3 people, 12.00%
  9. Application Site Vesicles (small bubble within a cell at application site): 3 people, 12.00%
  10. Drug Administration Error: 3 people, 12.00%

Common conditions people have *:

  1. High Blood Pressure: 2 people, 8.00%
  2. Neuralgia (pain in one or more nerves): 2 people, 8.00%
  3. Spinal Disorder (disease of spine a back bone): 2 people, 8.00%
  4. Sleep Disorder: 2 people, 8.00%
  5. Breakthrough Pain: 2 people, 8.00%
  6. Prostatomegaly (enlargement of the prostate): 2 people, 8.00%
  7. Gastric Disorder (disease of stomach): 2 people, 8.00%
  8. Depression: 2 people, 8.00%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 4.00%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl and have Application site scab?

Check whether Application site scab is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Application site scab and when was it recovered:

Expand to all the drugs that have ingredients of fentanyl citrate:

Alternative drugs to, pros and cons of Fentanyl:

Common Fentanyl side effects:

Browse all side effects of Fentanyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Application site scab treatments and more:

COVID vaccines that are related to Application site scab:

Common drugs associated with Application site scab:

All the drugs that are associated with Application site scab:

Common conditions associated with Application site scab:

All the conditions that are associated with Application site scab:

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Fentanyl) and Fentanyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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