Fish oil and Celiac disease - sprue - a phase IV clinical study of FDA data


Celiac disease - sprue is found among people who take Fish oil, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Fish oil and have Celiac disease - sprue. It is created by eHealthMe based on reports of 97,245 people who have side effects when taking Fish oil from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 03, 2023

97,245 people reported to have side effects when taking Fish oil.
Among them, 86 people (0.09%) have Celiac disease - sprue.

What is Fish oil?

Fish oil has active ingredients of fish oil. It is often used in high blood cholesterol. eHealthMe is studying from 100,059 Fish oil users for its effectiveness, alternative drugs and more.

What is Celiac disease - sprue?

Celiac disease - sprue (a disease of the small intestine) is found to be associated with 1,553 drugs and 1,081 conditions by eHealthMe.

Number of Fish oil and Celiac disease - sprue reports submitted per year:

Could Fish oil cause Celiac disease - sprue?

Gender of people who have Celiac disease - sprue when taking Fish oil *:

  • female: 74.19 %
  • male: 25.81 %

Age of people who have Celiac disease - sprue when taking Fish oil *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.63 %
  • 20-29: 13.16 %
  • 30-39: 5.26 %
  • 40-49: 10.53 %
  • 50-59: 23.68 %
  • 60+: 44.74 %

Common drugs people take besides Fish oil *:

  1. Benicar: 21 people, 24.42%
  2. Magnesium: 14 people, 16.28%
  3. Vitamin C: 10 people, 11.63%
  4. Calcium: 9 people, 10.47%
  5. Xyrem: 8 people, 9.30%
  6. Benicar Hct: 8 people, 9.30%
  7. Synthroid: 7 people, 8.14%
  8. Lantus: 7 people, 8.14%
  9. Nuvigil: 7 people, 8.14%
  10. Plavix: 7 people, 8.14%

Common side effects people have besides Celiac disease - sprue *:

  1. Hypotension (abnormally low blood pressure): 16 people, 18.60%
  2. Weight Decreased: 10 people, 11.63%
  3. Depression: 10 people, 11.63%
  4. Nausea (feeling of having an urge to vomit): 9 people, 10.47%
  5. Drug Ineffective: 9 people, 10.47%
  6. Diverticulum Intestinal (a pouch that is attached to the first part of the small intestine): 8 people, 9.30%
  7. Stress And Anxiety: 8 people, 9.30%
  8. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 7 people, 8.14%
  9. Rashes (redness): 7 people, 8.14%
  10. Abdominal Discomfort: 6 people, 6.98%

Common conditions people have *:

  1. High Blood Pressure: 26 people, 30.23%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 11.63%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 10.47%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 9.30%
  5. Cardiac Disorder: 5 people, 5.81%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 5.81%
  7. Osteoporosis (bones weak and more likely to break): 4 people, 4.65%
  8. Affective Disorder (mental disorder): 4 people, 4.65%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 4.65%
  10. Asthma: 4 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Fish oil and have Celiac disease - sprue?

Check whether Celiac disease - sprue is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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Common conditions associated with Celiac disease - sprue:

All the conditions that are associated with Celiac disease - sprue:

How the study uses the data?

The study uses data from the FDA. It is based on fish oil (the active ingredients of Fish oil) and Fish oil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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