Flector and Atrial fibrillation/flutter - a phase IV clinical study of FDA data


Atrial fibrillation/flutter is found among people who take Flector, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Flector and have Atrial fibrillation/flutter. It is created by eHealthMe based on reports of 4,962 people who have side effects when taking Flector from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

4,962 people reported to have side effects when taking Flector.
Among them, 18 people (0.36%) have Atrial fibrillation/flutter.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 4,999 Flector users for its effectiveness, alternative drugs and more.

What is Atrial fibrillation/flutter?

Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles) is found to be associated with 3,703 drugs and 3,524 conditions by eHealthMe.

Number of Flector and Atrial fibrillation/flutter reports submitted per year:

Could Flector cause Atrial fibrillation/flutter?

Time on Flector when people have Atrial fibrillation/flutter *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Atrial fibrillation/flutter when taking Flector *:

  • female: 70.59 %
  • male: 29.41 %

Age of people who have Atrial fibrillation/flutter when taking Flector *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 20 %
  • 50-59: 0.0 %
  • 60+: 80 %

Common drugs people take besides Flector *:

  1. Lyrica: 9 people, 50.00%
  2. Imitrex: 5 people, 27.78%
  3. Hydrocodone: 5 people, 27.78%
  4. Cialis: 5 people, 27.78%
  5. Cymbalta: 5 people, 27.78%
  6. Singulair: 4 people, 22.22%
  7. Lasix: 4 people, 22.22%
  8. Xanax: 4 people, 22.22%
  9. Mirapex: 4 people, 22.22%
  10. Premarin: 3 people, 16.67%

Common side effects people have besides Atrial fibrillation/flutter *:

  1. Weight Decreased: 5 people, 27.78%
  2. Breathing Difficulty: 5 people, 27.78%
  3. Weakness: 5 people, 27.78%
  4. Pneumonia: 4 people, 22.22%
  5. Gait Disturbance: 4 people, 22.22%
  6. Fall: 4 people, 22.22%
  7. Bleeding Into The Skin: 3 people, 16.67%
  8. Arrhythmias (irregular heartbeat): 3 people, 16.67%
  9. Ligament Injury: 3 people, 16.67%
  10. Laryngitis (inflammation of the larynx): 3 people, 16.67%

Common conditions people have *:

  1. Sleep Disorder: 5 people, 27.78%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 22.22%
  3. Migraine (headache): 3 people, 16.67%
  4. Sinus Congestion (blockage of sinus): 3 people, 16.67%
  5. Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 16.67%
  6. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 16.67%
  7. Psoriasis (immune-mediated disease that affects the skin): 3 people, 16.67%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 16.67%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 16.67%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Flector and have Atrial fibrillation/flutter?

Check whether Atrial fibrillation/flutter is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Atrial fibrillation/flutter and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac epolamine:

Alternative drugs to, pros and cons of Flector:

Common Flector side effects:

Browse all side effects of Flector:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Atrial fibrillation/flutter treatments and more:

COVID vaccines that are related to Atrial fibrillation/flutter:

Common drugs associated with Atrial fibrillation/flutter:

All the drugs that are associated with Atrial fibrillation/flutter:

Common conditions associated with Atrial fibrillation/flutter:

All the conditions that are associated with Atrial fibrillation/flutter:

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac epolamine (the active ingredients of Flector) and Flector (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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