Flector and Depression - a phase IV clinical study of FDA data


Depression is found among people who take Flector, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Flector and have Depression. It is created by eHealthMe based on reports of 4,962 people who have side effects when taking Flector from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 30, 2023

4,962 people reported to have side effects when taking Flector.
Among them, 66 people (1.33%) have Depression.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 4,999 Flector users for its effectiveness, alternative drugs and more.

What is Depression?

Depression is found to be associated with 3,994 drugs and 3,931 conditions by eHealthMe.

Number of Flector and Depression reports submitted per year:

Could Flector cause Depression?

Time on Flector when people have Depression *:

  • < 1 month: 66.67 %
  • 1 - 6 months: 6.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 26.67 %

Gender of people who have Depression when taking Flector *:

  • female: 85 %
  • male: 15 %

Age of people who have Depression when taking Flector *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5.0 %
  • 40-49: 12.5 %
  • 50-59: 30.0 %
  • 60+: 52.5 %

Common drugs people take besides Flector *:

  1. Lyrica: 19 people, 28.79%
  2. Hydrocodone: 9 people, 13.64%
  3. Aldactone: 8 people, 12.12%
  4. Diovan: 8 people, 12.12%
  5. Cymbalta: 8 people, 12.12%
  6. Celebrex: 8 people, 12.12%
  7. Savella: 8 people, 12.12%
  8. Augmentin: 8 people, 12.12%
  9. Prolia: 7 people, 10.61%
  10. Vitamin D3: 7 people, 10.61%

Common side effects people have besides Depression *:

  1. Stress And Anxiety: 30 people, 45.45%
  2. Fatigue (feeling of tiredness): 24 people, 36.36%
  3. Memory Loss: 17 people, 25.76%
  4. Weakness: 15 people, 22.73%
  5. Pain In Extremity: 15 people, 22.73%
  6. Fall: 14 people, 21.21%
  7. Joint Swelling: 13 people, 19.70%
  8. Weight Increased: 13 people, 19.70%
  9. Insomnia (sleeplessness): 13 people, 19.70%
  10. Fever: 12 people, 18.18%

Common conditions people have *:

  1. Fibromyalgia (a long-term condition which causes pain all over the body): 12 people, 18.18%
  2. Stress And Anxiety: 9 people, 13.64%
  3. Back Disorder: 7 people, 10.61%
  4. Pneumonia: 7 people, 10.61%
  5. High Blood Pressure: 7 people, 10.61%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 10.61%
  7. Hypersensitivity: 6 people, 9.09%
  8. Inflammation: 4 people, 6.06%
  9. Skin Disorder (skin disease): 4 people, 6.06%
  10. Autonomic Nervous System Imbalance (autonomic nervous system is of net equal emphasis): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Flector and have Depression?

Check whether Depression is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Depression and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac epolamine:

Alternative drugs to, pros and cons of Flector:

Common Flector side effects:

Browse all side effects of Flector:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Depression treatments and more:

COVID vaccines that are related to Depression:

Common drugs associated with Depression:

All the drugs that are associated with Depression:

Common conditions associated with Depression:

All the conditions that are associated with Depression:

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac epolamine (the active ingredients of Flector) and Flector (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: