Flexeril and Spinal cord trauma - a phase IV clinical study of FDA data


Spinal cord trauma is found among people who take Flexeril, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Flexeril and have Spinal cord trauma. It is created by eHealthMe based on reports of 34,296 people who have side effects when taking Flexeril from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 18, 2023

34,296 people reported to have side effects when taking Flexeril.
Among them, 11 people (0.03%) have Spinal cord trauma.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 37,778 Flexeril users for its effectiveness, alternative drugs and more.

What is Spinal cord trauma?

Spinal cord trauma is found to be associated with 971 drugs and 478 conditions by eHealthMe.

Number of Flexeril and Spinal cord trauma reports submitted per year:

Could Flexeril cause Spinal cord trauma?

Time on Flexeril when people have Spinal cord trauma *:

  • < 1 month: 66.67 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Spinal cord trauma when taking Flexeril *:

  • female: 81.82 %
  • male: 18.18 %

Age of people who have Spinal cord trauma when taking Flexeril *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 50 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 50 %

Common drugs people take besides Flexeril *:

  1. Proair Hfa: 5 people, 45.45%
  2. Lyrica: 5 people, 45.45%
  3. Prevacid: 4 people, 36.36%
  4. Percocet: 4 people, 36.36%
  5. Intron A: 3 people, 27.27%
  6. Prilosec: 3 people, 27.27%
  7. Meclizine: 3 people, 27.27%
  8. Lipitor: 3 people, 27.27%
  9. Tylenol: 3 people, 27.27%
  10. Klor-Con: 3 people, 27.27%

Common side effects people have besides Spinal cord trauma *:

  1. Abdominal Pain: 3 people, 27.27%
  2. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 27.27%
  3. Viral Diarrhea: 3 people, 27.27%
  4. Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 27.27%
  5. Acute Myocardial Infarction (acute heart attack): 2 people, 18.18%
  6. Cataract (clouding of the lens inside the eye): 2 people, 18.18%
  7. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 18.18%
  8. Pain: 2 people, 18.18%
  9. White Blood Cell Count Decreased: 2 people, 18.18%
  10. Urinary Tract Infection: 2 people, 18.18%

Common conditions people have *:

  1. Eosinophilia (eosinophil count in the peripheral blood exceeds): 3 people, 27.27%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 18.18%
  3. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 18.18%
  4. Viral Infection: 1 person, 9.09%
  5. Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 9.09%
  6. Bacterial Infection: 1 person, 9.09%
  7. Blood Urine Present: 1 person, 9.09%
  8. Depression: 1 person, 9.09%
  9. Diabetes: 1 person, 9.09%
  10. Gastric Ph Decreased: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and have Spinal cord trauma?

Check whether Spinal cord trauma is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Spinal cord trauma and when was it recovered:

Expand to all the drugs that have ingredients of cyclobenzaprine hydrochloride:

Alternative drugs to, pros and cons of Flexeril:

Common Flexeril side effects:

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Spinal cord trauma treatments and more:

COVID vaccines that are related to Spinal cord trauma:

Common drugs associated with Spinal cord trauma:

All the drugs that are associated with Spinal cord trauma:

Common conditions associated with Spinal cord trauma:

All the conditions that are associated with Spinal cord trauma:

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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