Fluorouracil and Hyperacusis - a phase IV clinical study of FDA data


Hyperacusis is reported only by a few people who take Fluorouracil.

The phase IV clinical study analyzes which people take Fluorouracil and have Hyperacusis. It is created by eHealthMe based on reports of 91,426 people who have side effects while taking Fluorouracil from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 21, 2023

91,426 people reported to have side effects when taking Fluorouracil.
Among them, 4 people (0.0%) have Hyperacusis.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 91,572 Fluorouracil users for its effectiveness, alternative drugs and more.

What is Hyperacusis?

Hyperacusis (disorder in loudness perception) is found to be associated with 1,083 drugs and 594 conditions by eHealthMe.

Number of Fluorouracil and Hyperacusis reports submitted per year:

Could Fluorouracil cause Hyperacusis?

Time on Fluorouracil when people have Hyperacusis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hyperacusis when taking Fluorouracil *:

  • female: 25 %
  • male: 75 %

Age of people who have Hyperacusis when taking Fluorouracil *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 25 %
  • 50-59: 25 %
  • 60+: 50 %

Common drugs people take besides Fluorouracil *:

  1. Oxaliplatin: 1 person, 25.00%
  2. Metoclopramide: 1 person, 25.00%
  3. Kytril: 1 person, 25.00%
  4. Emend: 1 person, 25.00%
  5. Cyclophosphamide: 1 person, 25.00%
  6. Cisplatin: 1 person, 25.00%
  7. Camptosar: 1 person, 25.00%

Common side effects people have besides Hyperacusis *:

  1. Weakness: 1 person, 25.00%
  2. Visual Acuity Reduced (reduced clearness of vision): 1 person, 25.00%
  3. Abnormal Faeces (abnormal stool): 1 person, 25.00%
  4. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 25.00%
  5. Back Pain: 1 person, 25.00%
  6. Diarrhea: 1 person, 25.00%
  7. Dizziness: 1 person, 25.00%
  8. Ear Disorder: 1 person, 25.00%
  9. Faecaloma (hard mass of fecal matter): 1 person, 25.00%
  10. Fluid Intake Reduced: 1 person, 25.00%

Common conditions people have *:

  1. Oesophageal Carcinoma (cancer tumour of oesophagus): 1 person, 25.00%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Hyperacusis?

Check whether Hyperacusis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Hyperacusis and when was it recovered:

Expand to all the drugs that have ingredients of fluorouracil:

Alternative drugs to, pros and cons of Fluorouracil:

Common Fluorouracil side effects:

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Hyperacusis treatments and more:

COVID vaccines that are related to Hyperacusis:

Common drugs associated with Hyperacusis:

All the drugs that are associated with Hyperacusis:

Common conditions associated with Hyperacusis:

All the conditions that are associated with Hyperacusis:

How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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