Fluorouracil and Lip haemorrhage - a phase IV clinical study of FDA data


Lip haemorrhage is found among people who take Fluorouracil, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Fluorouracil and have Lip haemorrhage. It is created by eHealthMe based on reports of 84,198 people who have side effects when taking Fluorouracil from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 11, 2022

84,198 people reported to have side effects when taking Fluorouracil.
Among them, 10 people (0.01%) have Lip haemorrhage.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 84,338 Fluorouracil users for its effectiveness, alternative drugs and more.

What is Lip haemorrhage?

Lip haemorrhage (bleeding lip) is found to be associated with 567 drugs and 345 conditions by eHealthMe.

Number of Fluorouracil and Lip haemorrhage reports submitted per year:

Could Fluorouracil cause Lip haemorrhage?

Time on Fluorouracil when people have Lip haemorrhage *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Lip haemorrhage when taking Fluorouracil *:

  • female: 37.5 %
  • male: 62.5 %

Age of people who have Lip haemorrhage when taking Fluorouracil *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Fluorouracil *:

  1. Taxotere: 2 people, 20.00%
  2. Mitomycin: 2 people, 20.00%
  3. Decadron: 2 people, 20.00%
  4. Zyrtec: 1 person, 10.00%
  5. Xiidra: 1 person, 10.00%
  6. Vitamin C: 1 person, 10.00%
  7. Diclofenac: 1 person, 10.00%

Common side effects people have besides Lip haemorrhage *:

  1. Diarrhea: 4 people, 40.00%
  2. Lip Swelling: 3 people, 30.00%
  3. Nausea And Vomiting: 2 people, 20.00%
  4. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 2 people, 20.00%
  5. Stomatitis (inflammation of mucous membrane of mouth): 2 people, 20.00%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 20.00%
  7. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 20.00%
  8. Lip Pain: 2 people, 20.00%
  9. Fever: 2 people, 20.00%
  10. Temperature Intolerance (inability to go in temperature): 1 person, 10.00%

Common conditions people have *:

  1. Precancerous Skin Lesion: 3 people, 30.00%
  2. Oropharyngeal Cancer Recurrent (cancer of oropharynx reoccurs): 2 people, 20.00%
  3. Actinic Keratosis (skin disease due to sun exposure): 2 people, 20.00%
  4. Skin Cancer: 1 person, 10.00%
  5. Oral Disorder (mouth disease): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Lip haemorrhage?

Check whether Lip haemorrhage is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Lip haemorrhage and when was it recovered:

Expand to all the drugs that have ingredients of fluorouracil:

Alternative drugs to, pros and cons of Fluorouracil:

Common Fluorouracil side effects:

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Lip haemorrhage treatments and more:

COVID vaccines that are related to Lip haemorrhage:

All the drugs that are associated with Lip haemorrhage:

All the conditions that are associated with Lip haemorrhage:

How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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