Flurbiprofen and International normalised ratio increased - a phase IV clinical study of FDA data

Summary:

International normalised ratio increased is found among people who take Flurbiprofen, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Flurbiprofen and have International normalised ratio increased. It is created by eHealthMe based on reports of 2,341 people who have side effects when taking Flurbiprofen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 12, 2023

2,341 people reported to have side effects when taking Flurbiprofen.
Among them, 8 people (0.34%) have International normalised ratio increased.

What is Flurbiprofen?

Flurbiprofen has active ingredients of flurbiprofen. It is often used in rheumatoid arthritis. eHealthMe is studying from 2,356 Flurbiprofen users for its effectiveness, alternative drugs and more.

What is International normalised ratio increased?

International normalised ratio increased is found to be associated with 2,259 drugs and 1,645 conditions by eHealthMe.

Number of Flurbiprofen and International normalised ratio increased reports submitted per year:

Could Flurbiprofen cause International normalised ratio increased?

Time on Flurbiprofen when people have International normalised ratio increased *:

Gender of people who have International normalised ratio increased when taking Flurbiprofen *:

female: 42.86 %
male: 57.14 %

Age of people who have International normalised ratio increased when taking Flurbiprofen *:

Common drugs people take besides Flurbiprofen *:

Cefazolin: 3 people, 37.50%
Warfarin Sodium: 3 people, 37.50%
Phenytoin: 3 people, 37.50%
Aldactone: 2 people, 25.00%
Allopurinol: 2 people, 25.00%
Isoniazid: 2 people, 25.00%
Folic Acid: 2 people, 25.00%
Minocycline Hydrochloride: 2 people, 25.00%
Fosamax: 2 people, 25.00%
Clindamycin Hydrochloride: 2 people, 25.00%

Common side effects people have besides International normalised ratio increased *:

Haemoglobin Decreased: 3 people, 37.50%
Renal Impairment (severely reduced kidney function): 2 people, 25.00%
Hypokalemia (low potassium): 2 people, 25.00%
Itching: 2 people, 25.00%
Lactic Acidosis (low ph in body tissues): 2 people, 25.00%
Clavicle Fracture: 2 people, 25.00%
C-Reactive Protein Increased: 2 people, 25.00%
Platelet Count Increased: 2 people, 25.00%
Blood Bilirubin Increased: 2 people, 25.00%
Pneumonia: 2 people, 25.00%

Common conditions people have *:

Type 2 Diabetes: 2 people, 25.00%
Sinusitis (inflammation of sinus): 2 people, 25.00%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 2 people, 25.00%
C-Reactive Protein Increased: 2 people, 25.00%
Neuropsychiatric Lupus (the various psychiatric and neurologic symptoms due to a multi system inflammatory disorder): 1 person, 12.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 12.50%
Liver Disorder (liver diseases): 1 person, 12.50%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 1 person, 12.50%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 12.50%
Headache (pain in head): 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Flurbiprofen and have International normalised ratio increased?

Check whether International normalised ratio increased is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Yaylaci S, Kocayigit I, Genc A, Tamer A, Gunduz H, "Sinus bradycardia caused by flurbiprofen intoxication", Nigerian Journal of Cardiology, 2015 Jan .

Related studies

How severe was International normalised ratio increased and when was it recovered:

International normalised ratio increased in Flurbiprofen

Expand to all the drugs that have ingredients of flurbiprofen:

International normalised ratio increased and drugs with ingredients of flurbiprofen

Alternative drugs to, pros and cons of Flurbiprofen:

Flurbiprofen (2,356 reports)

Common Flurbiprofen side effects:

Fever: 151 reports
Pneumonia: 116 reports
High blood pressure: 109 reports
Angioedema (rapid swelling of the dermis): 102 reports

Browse all side effects of Flurbiprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

International normalised ratio increased treatments and more:

International normalised ratio increased (38,886 reports)

COVID vaccines that are related to International normalised ratio increased:

Common drugs associated with International normalised ratio increased:

All the drugs that are associated with International normalised ratio increased:

International normalised ratio increased (2,259 drugs)

Common conditions associated with International normalised ratio increased:

Atrial fibrillation/flutter: 7,036 reports
High blood pressure: 1,515 reports
Deep venous thrombosis: 1,396 reports
Pulmonary embolism: 1,135 reports
Stroke: 909 reports

All the conditions that are associated with International normalised ratio increased:

International normalised ratio increased (1,645 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on flurbiprofen (the active ingredients of Flurbiprofen) and Flurbiprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.