Review: could Folic Acid cause Multiple Sclerosis?


Multiple sclerosis is found among people who take Folic Acid, especially for people who are female, 50-59 old , have been taking the drug for 1 - 6 months, also take medication Methotrexate, and have Multiple sclerosis . We study 104,383 people who have side effects while taking Folic acid from FDA and social media. Among them, 202 have Multiple sclerosis. Find out below who they are, when they have Multiple sclerosis and more.

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Folic Acid

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. (latest outcomes from Folic acid 105,359 users)

Multiple Sclerosis

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) has been reported by people with multiple sclerosis, relapsing-remitting multiple sclerosis, depression, pain, gait disturbance (latest reports from 423,464 Multiple sclerosis patients).

On Oct, 26, 2016

104,383 people reported to have side effects when taking Folic Acid.
Among them, 202 people (0.19%) have Multiple Sclerosis

Number of reports submitted per year:

Could Folic acid cause Multiple sclerosis?

Time on Folic Acid when people have Multiple Sclerosis *:

  • < 1 month: 33.33 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Multiple Sclerosis when taking Folic Acid *:

  • female: 79.1 %
  • male: 20.9 %

Age of people who have Multiple Sclerosis when taking Folic Acid *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.16 %
  • 30-39: 13.95 %
  • 40-49: 33.72 %
  • 50-59: 38.37 %
  • 60+: 12.79 %

Top conditions involved for these people *:

  • Multiple Sclerosis (64 people, 31.68%)
  • Rheumatoid Arthritis (40 people, 19.80%)
  • Relapsing-Remitting Multiple Sclerosis (13 people, 6.44%)
  • Osteoporosis (13 people, 6.44%)
  • Depression (11 people, 5.45%)

Top co-used drugs for these people *:

  • Methotrexate (74 people, 36.63%)
  • Enbrel (37 people, 18.32%)
  • Avonex (37 people, 18.32%)
  • Baclofen (35 people, 17.33%)
  • Betaseron (32 people, 15.84%)

Top other side effects for these people *:

  • Condition Aggravated (36 people, 17.82%)
  • Gait Disturbance (23 people, 11.39%)
  • Headache (21 people, 10.40%)
  • Fatigue (19 people, 9.41%)
  • Depression (19 people, 9.41%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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