Fosamax and Cardiac murmur - a phase IV clinical study of FDA data
We study 102,220 people who have side effects when taking Fosamax. Cardiac murmur is found, especially among people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take Alendronate sodium and have High blood pressure.
The phase IV clinical study analyzes which people take Fosamax and have Cardiac murmur. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
102,220 people reported to have side effects when taking Fosamax.
Among them, 1,338 people (1.31%) have Cardiac murmur.
What is Fosamax?
Fosamax has active ingredients of alendronate sodium. It is used in osteoporosis. Currently, eHealthMe is studying from 103,235 Fosamax users.
What is Cardiac murmur?
Cardiac murmur (an heart sound in valve abnormality) is found to be associated with 1,819 drugs and 1,127 conditions by eHealthMe. Currently, we are studying 14,203 people who have Cardiac murmur.
Number of Fosamax and Cardiac murmur reports submitted per year:
Time on Fosamax when people have Cardiac murmur *:
Gender of people who have Cardiac murmur when taking Fosamax*:
Age of people who have Cardiac murmur when taking Fosamax *:
Common drugs people take besides Fosamax *:
Common side effects people have besides Cardiac murmur *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Fosamax and have Cardiac murmur?Check whether Cardiac murmur is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
Fosamax side effects by duration, gender and age:
- Fosamax side effects (103,235 reports)
Cardiac murmur treatments and more:
- Cardiac murmur (14,203 reports)
Common drugs associated with Cardiac murmur:
- Paxil: 2,240 reports
- Fosamax: 1,338 reports
- Aspirin: 1,138 reports
- Furosemide: 976 reports
- Prednisone: 973 reports
- Vioxx: 899 reports
- Zofran: 829 reports
- Lasix: 825 reports
- Digoxin: 772 reports
- Zoloft: 642 reports
All the drugs that are associated with Cardiac murmur:
- Cardiac murmur (1,819 drugs)
Common conditions associated with Cardiac murmur:
- Depression: 1,406 reports
- Osteoporosis: 1,084 reports
- High blood pressure: 789 reports
- Stress and anxiety: 707 reports
All the conditions that are associated with Cardiac murmur:
- Cardiac murmur (1,127 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on alendronate sodium (the active ingredients of Fosamax) and Fosamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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