Fosamax and Tongue discoloration - a phase IV clinical study of FDA data

Summary:

Tongue discoloration is found among people who take Fosamax, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Fosamax and have Tongue discoloration. It is created by eHealthMe based on reports of 98,641 people who have side effects when taking Fosamax from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jun, 04, 2023

98,641 people reported to have side effects when taking Fosamax.
Among them, 131 people (0.13%) have Tongue discoloration.

What is Fosamax?

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 99,637 Fosamax users for its effectiveness, alternative drugs and more.

What is Tongue discoloration?

Tongue discoloration is found to be associated with 1,260 drugs and 589 conditions by eHealthMe.

Number of Fosamax and Tongue discoloration reports submitted per year:

Could Fosamax cause Tongue discoloration?

* Approximation only. Some reports may have incomplete information.

Do you take Fosamax and have Tongue discoloration?

Check whether Tongue discoloration is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .

Related studies

How severe was Tongue discoloration and when was it recovered:

Tongue discoloration in Fosamax

Expand to all the drugs that have ingredients of alendronate sodium:

Tongue discoloration and drugs with ingredients of alendronate sodium (146 reports)

Alternative drugs to, pros and cons of Fosamax:

Fosamax (99,637 reports)

Common Fosamax side effects:

Pain: 12,372 reports
Joint pain: 10,844 reports
Fatigue (feeling of tiredness): 10,750 reports
High blood pressure: 10,439 reports
Stress and anxiety: 9,609 reports
Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 9,374 reports

Browse all side effects of Fosamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Tongue discoloration treatments and more:

Tongue discoloration (4,696 reports)

COVID vaccines that are related to Tongue discoloration:

Common drugs associated with Tongue discoloration:

All the drugs that are associated with Tongue discoloration:

Tongue discoloration (1,260 drugs)

Common conditions associated with Tongue discoloration:

High blood pressure: 252 reports
Rheumatoid arthritis: 182 reports
Chronic obstructive pulmonary disease: 181 reports
Asthma: 168 reports
High blood cholesterol: 154 reports
Depression: 141 reports
Osteoporosis: 133 reports
Pain: 132 reports
Multiple sclerosis: 107 reports
Stress and anxiety: 105 reports

All the conditions that are associated with Tongue discoloration:

Tongue discoloration (589 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alendronate sodium (the active ingredients of Fosamax) and Fosamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.