Gabapentin and Lipohypertrophy - a phase IV clinical study of FDA data


Lipohypertrophy is reported only by a few people who take Gabapentin.

The phase IV clinical study analyzes which people take Gabapentin and have Lipohypertrophy. It is created by eHealthMe based on reports of 264,649 people who have side effects while taking Gabapentin from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 01, 2022

264,649 people reported to have side effects when taking Gabapentin.
Among them, 5 people (0.0%) have Lipohypertrophy.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 273,137 Gabapentin users for its effectiveness, alternative drugs and more.

What is Lipohypertrophy?

Lipohypertrophy (a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin) is found to be associated with 353 drugs and 159 conditions by eHealthMe.

Number of Gabapentin and Lipohypertrophy reports submitted per year:

Could Gabapentin cause Lipohypertrophy?

Gender of people who have Lipohypertrophy when taking Gabapentin *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Lipohypertrophy when taking Gabapentin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 50 %
  • 30-39: 0.0 %
  • 40-49: 25 %
  • 50-59: 25 %
  • 60+: 0.0 %

Common drugs people take besides Gabapentin *:

  1. Vitamin D: 2 people, 40.00%
  2. Somavert: 2 people, 40.00%
  3. Sertraline: 2 people, 40.00%
  4. Nature-Throid: 2 people, 40.00%
  5. Biotin: 2 people, 40.00%
  6. Zocor: 1 person, 20.00%
  7. Symtuza: 1 person, 20.00%
  8. Rivaroxaban: 1 person, 20.00%
  9. Rebif: 1 person, 20.00%
  10. Metformin: 1 person, 20.00%

Common side effects people have besides Lipohypertrophy *:

  1. Drug Ineffective: 2 people, 40.00%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 40.00%
  3. Urinary Tract Infection: 1 person, 20.00%
  4. Skin Burning Sensation: 1 person, 20.00%
  5. Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem): 1 person, 20.00%
  6. Back Pain: 1 person, 20.00%
  7. Confusional State: 1 person, 20.00%
  8. Eye Pain: 1 person, 20.00%
  9. Gait Disturbance: 1 person, 20.00%
  10. Injection Site Atrophy (injection site wasting or decreasing in size of a body organ, tissue, or part): 1 person, 20.00%

Common conditions people have *:

  1. Thyroid Diseases: 2 people, 40.00%
  2. Blood Growth Hormone Increased: 2 people, 40.00%
  3. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 2 people, 40.00%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 20.00%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 20.00%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Gabapentin and have Lipohypertrophy?

Check whether Lipohypertrophy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Lipohypertrophy and when was it recovered:

Expand to all the drugs that have ingredients of gabapentin:

Alternative drugs to, pros and cons of Gabapentin:

Common Gabapentin side effects:

Browse all side effects of Gabapentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Lipohypertrophy treatments and more:

COVID vaccines that are related to Lipohypertrophy:

All the drugs that are associated with Lipohypertrophy:

Common conditions associated with Lipohypertrophy:

All the conditions that are associated with Lipohypertrophy:

How the study uses the data?

The study uses data from the FDA. It is based on gabapentin (the active ingredients of Gabapentin) and Gabapentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: