Gilotrif and Lip injury - a phase IV clinical study of FDA data


Lip injury is reported only by a few people who take Gilotrif.

The phase IV clinical study analyzes which people take Gilotrif and have Lip injury. It is created by eHealthMe based on reports of 5,719 people who have side effects while taking Gilotrif from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 16, 2022

5,719 people reported to have side effects when taking Gilotrif.
Among them, 4 people (0.07%) have Lip injury.

What is Gilotrif?

Gilotrif has active ingredients of afatinib dimaleate. eHealthMe is studying from 5,428 Gilotrif users for its effectiveness, alternative drugs and more.

What is Lip injury?

Lip injury is found to be associated with 426 drugs and 270 conditions by eHealthMe.

Number of Gilotrif and Lip injury reports submitted per year:

Could Gilotrif cause Lip injury?

Time on Gilotrif when people have Lip injury *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Lip injury when taking Gilotrif *:

  • female: 50 %
  • male: 50 %

Age of people who have Lip injury when taking Gilotrif *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 25 %
  • 60+: 75 %

Common drugs people take besides Gilotrif *:

  1. Oxycodone: 2 people, 50.00%
  2. Ondansetron: 2 people, 50.00%
  3. Miralax: 2 people, 50.00%
  4. Megace: 2 people, 50.00%
  5. Flomax: 2 people, 50.00%
  6. Amlodipine: 2 people, 50.00%
  7. Symbicort: 1 person, 25.00%
  8. Imodium: 1 person, 25.00%
  9. Hydrocodone: 1 person, 25.00%

Common side effects people have besides Lip injury *:

  1. Diarrhea: 4 people, 100.00%
  2. Weight Decreased: 3 people, 75.00%
  3. Dizziness: 3 people, 75.00%
  4. Acne (skin problems that cause pimples): 3 people, 75.00%
  5. Taste - Impaired: 3 people, 75.00%
  6. Head Injury: 2 people, 50.00%
  7. Memory Loss: 2 people, 50.00%
  8. Breathing Difficulty: 2 people, 50.00%
  9. Constipation: 2 people, 50.00%
  10. Cuts And Puncture Wounds: 2 people, 50.00%

Common conditions people have *:

  1. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 75.00%
  2. Lung Adenocarcinoma (a form of non-small cell lung cancer): 1 person, 25.00%
  3. Cough: 1 person, 25.00%
  4. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Gilotrif and have Lip injury?

Check whether Lip injury is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Lip injury and when was it recovered:

Expand to all the drugs that have ingredients of afatinib dimaleate:

Alternative drugs to, pros and cons of Gilotrif:

Common Gilotrif side effects:

Browse all side effects of Gilotrif:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Lip injury treatments and more:

COVID vaccines that are related to Lip injury:

All the drugs that are associated with Lip injury:

Common conditions associated with Lip injury:

All the conditions that are associated with Lip injury:

How the study uses the data?

The study uses data from the FDA. It is based on afatinib dimaleate (the active ingredients of Gilotrif) and Gilotrif (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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