Glycopyrrolate and Hepatic encephalopathy - a phase IV clinical study of FDA data


Hepatic encephalopathy is found among people who take Glycopyrrolate, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Glycopyrrolate and have Hepatic encephalopathy. It is created by eHealthMe based on reports of 3,707 people who have side effects when taking Glycopyrrolate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 03, 2022

3,707 people reported to have side effects when taking Glycopyrrolate.
Among them, 7 people (0.19%) have Hepatic encephalopathy.

What is Glycopyrrolate?

Glycopyrrolate has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 3,772 Glycopyrrolate users for its effectiveness, alternative drugs and more.

What is Hepatic encephalopathy?

Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure) is found to be associated with 1,647 drugs and 1,172 conditions by eHealthMe.

Number of Glycopyrrolate and Hepatic encephalopathy reports submitted per year:

Could Glycopyrrolate cause Hepatic encephalopathy?

Gender of people who have Hepatic encephalopathy when taking Glycopyrrolate *:

  • female: 71.43 %
  • male: 28.57 %

Age of people who have Hepatic encephalopathy when taking Glycopyrrolate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 14.29 %
  • 60+: 85.71 %

Common drugs people take besides Glycopyrrolate *:

  1. Lasix: 6 people, 85.71%
  2. Morphine: 6 people, 85.71%
  3. Imuran: 5 people, 71.43%
  4. Melatonin: 5 people, 71.43%
  5. Ondansetron: 5 people, 71.43%
  6. Potassium: 5 people, 71.43%
  7. Heparin: 5 people, 71.43%
  8. Multivitamin: 5 people, 71.43%
  9. Evista: 5 people, 71.43%
  10. Premarin: 5 people, 71.43%

Common side effects people have besides Hepatic encephalopathy *:

  1. Itching: 6 people, 85.71%
  2. Breathing Difficulty: 6 people, 85.71%
  3. Rib Fracture: 6 people, 85.71%
  4. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 6 people, 85.71%
  5. Pulmonary Oedema (fluid accumulation in the lungs): 6 people, 85.71%
  6. Autoimmune Hepatitis: 5 people, 71.43%
  7. Ascites (accumulation of fluid in the abdominal cavity): 5 people, 71.43%
  8. Disease Progression: 5 people, 71.43%
  9. Fall: 5 people, 71.43%
  10. Fluid Overload (too much fluid in the blood): 5 people, 71.43%

Common conditions people have *:

  1. Portopulmonary Hypertension (coexistence of portal and pulmonary hypertension): 5 people, 71.43%
  2. Multiple Myeloma (cancer of the plasma cells): 1 person, 14.29%
  3. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 1 person, 14.29%
  4. High Blood Pressure: 1 person, 14.29%
  5. High Blood Cholesterol: 1 person, 14.29%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Glycopyrrolate and have Hepatic encephalopathy?

Check whether Hepatic encephalopathy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Hepatic encephalopathy and when was it recovered:

Expand to all the drugs that have ingredients of glycopyrrolate:

Alternative drugs to, pros and cons of Glycopyrrolate:

Common Glycopyrrolate side effects:

Browse all side effects of Glycopyrrolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Hepatic encephalopathy treatments and more:

COVID vaccines that are related to Hepatic encephalopathy:

Common drugs associated with Hepatic encephalopathy:

All the drugs that are associated with Hepatic encephalopathy:

Common conditions associated with Hepatic encephalopathy:

All the conditions that are associated with Hepatic encephalopathy:

How the study uses the data?

The study uses data from the FDA. It is based on glycopyrrolate (the active ingredients of Glycopyrrolate) and Glycopyrrolate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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