Gralise and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is found among people who take Gralise, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Gralise and have Joint swelling. It is created by eHealthMe based on reports of 4,070 people who have side effects when taking Gralise from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 08, 2022

4,070 people reported to have side effects when taking Gralise.
Among them, 24 people (0.59%) have Joint swelling.


What is Gralise?

Gralise has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 4,176 Gralise users for its effectiveness, alternative drugs and more.

What is Joint swelling?

Joint swelling is found to be associated with 3,157 drugs and 2,703 conditions by eHealthMe.

Number of Gralise and Joint swelling reports submitted per year:

Could Gralise cause Joint swelling?

Time on Gralise when people have Joint swelling *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Joint swelling when taking Gralise *:

  • female: 64.71 %
  • male: 35.29 %

Age of people who have Joint swelling when taking Gralise *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 30 %
  • 60+: 60 %

Common drugs people take besides Gralise *:

  1. Metformin: 5 people, 20.83%
  2. Magnesium: 5 people, 20.83%
  3. Amlodipine: 4 people, 16.67%
  4. Humira: 4 people, 16.67%
  5. Fish Oil: 3 people, 12.50%
  6. Ambien: 3 people, 12.50%
  7. Valium: 2 people, 8.33%
  8. Dexilant: 2 people, 8.33%
  9. Fluoxetine: 2 people, 8.33%
  10. Lexapro: 2 people, 8.33%

Common side effects people have besides Joint swelling *:

  1. Peripheral Swelling: 6 people, 25.00%
  2. Joint Pain: 4 people, 16.67%
  3. Impaired Healing: 4 people, 16.67%
  4. Nausea (feeling of having an urge to vomit): 4 people, 16.67%
  5. Gait Disturbance: 4 people, 16.67%
  6. Pain In Extremity: 4 people, 16.67%
  7. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 3 people, 12.50%
  8. Pain: 3 people, 12.50%
  9. Diarrhea: 3 people, 12.50%
  10. Abdominal Distension: 3 people, 12.50%

Common conditions people have *:

  1. High Blood Pressure: 4 people, 16.67%
  2. Neuropathy Peripheral (surface nerve damage): 4 people, 16.67%
  3. Migraine (headache): 4 people, 16.67%
  4. Diabetes: 3 people, 12.50%
  5. Pain: 3 people, 12.50%
  6. Sleep Disorder: 3 people, 12.50%
  7. High Blood Cholesterol: 3 people, 12.50%
  8. Insomnia (sleeplessness): 2 people, 8.33%
  9. Brain Neoplasm (tumour of brain): 2 people, 8.33%
  10. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Gralise and have Joint swelling?

Check whether Joint swelling is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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Expand to all the drugs that have ingredients of gabapentin:

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Common Gralise side effects:

Browse all side effects of Gralise:

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Joint swelling treatments and more:

COVID vaccines that are related to Joint swelling:

Common drugs associated with Joint swelling:

All the drugs that are associated with Joint swelling:

Common conditions associated with Joint swelling:

All the conditions that are associated with Joint swelling:

How the study uses the data?

The study uses data from the FDA. It is based on gabapentin (the active ingredients of Gralise) and Gralise (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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