Guanfacine hydrochloride and Sleep disorder - a phase IV clinical study of FDA data


Sleep disorder is found among people who take Guanfacine hydrochloride, especially for people who are male, 2-9 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Guanfacine hydrochloride and have Sleep disorder. It is created by eHealthMe based on reports of 595 people who have side effects when taking Guanfacine hydrochloride from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 05, 2023

595 people reported to have side effects when taking Guanfacine hydrochloride.
Among them, 8 people (1.34%) have Sleep disorder.

What is Guanfacine hydrochloride?

Guanfacine hydrochloride has active ingredients of guanfacine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 885 Guanfacine hydrochloride users for its effectiveness, alternative drugs and more.

What is Sleep disorder?

Sleep disorder is found to be associated with 2,856 drugs and 2,452 conditions by eHealthMe.

Number of Guanfacine hydrochloride and Sleep disorder reports submitted per year:

Could Guanfacine hydrochloride cause Sleep disorder?

Time on Guanfacine hydrochloride when people have Sleep disorder *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Sleep disorder when taking Guanfacine hydrochloride *:

  • female: 12.5 %
  • male: 87.5 %

Age of people who have Sleep disorder when taking Guanfacine hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 37.5 %
  • 10-19: 37.5 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 0.0 %
  • 60+: 12.5 %

Common drugs people take besides Guanfacine hydrochloride *:

  1. Clonazepam: 4 people, 50.00%
  2. Inositol: 3 people, 37.50%
  3. Methylphenidate: 3 people, 37.50%
  4. Miralax: 3 people, 37.50%
  5. Fish Oil: 3 people, 37.50%
  6. Clozapine: 3 people, 37.50%
  7. Gabapentin: 3 people, 37.50%
  8. Rozerem: 2 people, 25.00%
  9. Risperdal: 2 people, 25.00%
  10. Singulair: 2 people, 25.00%

Common side effects people have besides Sleep disorder *:

  1. Irritability: 5 people, 62.50%
  2. Agitation (state of anxiety or nervous excitement): 4 people, 50.00%
  3. Depressed Mood: 4 people, 50.00%
  4. Weight Decreased: 3 people, 37.50%
  5. Excessive Masturbation: 3 people, 37.50%
  6. Affective Disorder (mental disorder): 3 people, 37.50%
  7. Aggression: 3 people, 37.50%
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 3 people, 37.50%
  9. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 37.50%
  10. Bedwetting: 3 people, 37.50%

Common conditions people have *:

  1. Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 2 people, 25.00%
  2. Psychomotor Hyperactivity (feelings of extreme restlessness): 1 person, 12.50%
  3. Immunodeficiency Common Variable: 1 person, 12.50%
  4. Depression: 1 person, 12.50%
  5. Anger: 1 person, 12.50%
  6. Aggression: 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Guanfacine hydrochloride and have Sleep disorder?

Check whether Sleep disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Sleep disorder and when was it recovered:

Expand to all the drugs that have ingredients of guanfacine hydrochloride:

Alternative drugs to, pros and cons of Guanfacine hydrochloride:

Sleep disorder treatments and more:

COVID vaccines that are related to Sleep disorder:

Common drugs associated with Sleep disorder:

All the drugs that are associated with Sleep disorder:

Common conditions associated with Sleep disorder:

All the conditions that are associated with Sleep disorder:

How the study uses the data?

The study uses data from the FDA. It is based on guanfacine hydrochloride (the active ingredients of Guanfacine hydrochloride) and Guanfacine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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