Haldol and Dupuytren's contracture - a phase IV clinical study of FDA data
Summary:
Dupuytren's contracture is reported only by a few people who take Haldol.
The phase IV clinical study analyzes which people take Haldol and have Dupuytren's contracture. It is created by eHealthMe based on reports of 21,383 people who have side effects while taking Haldol from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
21,383 people reported to have side effects when taking Haldol.
Among them, 1 person (0.0%) has Dupuytren's contracture.
What is Haldol?
Haldol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 21,044 Haldol users for its effectiveness, alternative drugs and more.
What is Dupuytren's contracture?
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 445 drugs and 208 conditions by eHealthMe.
Number of Haldol and Dupuytren's contracture reports submitted per year:

Common drugs people take besides Haldol *:
- Zometa: 1 person, 100.00%
- Xanax: 1 person, 100.00%
- Warfarin Sodium: 1 person, 100.00%
- Roxanol: 1 person, 100.00%
- Omeprazole: 1 person, 100.00%
- Neurontin: 1 person, 100.00%
- Macrobid: 1 person, 100.00%
- Lasix: 1 person, 100.00%
- Heparin: 1 person, 100.00%
- Fentanyl: 1 person, 100.00%
Common side effects people have besides Dupuytren's contracture *:
- Weight Decreased: 1 person, 100.00%
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 1 person, 100.00%
- Death: 1 person, 100.00%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 100.00%
- Deformity (disfigurement): 1 person, 100.00%
- Depression: 1 person, 100.00%
- Dermatophytosis (inflammation of the skin and underlying muscle tissue): 1 person, 100.00%
- Dermoid Cyst (an abnormal growth (teratoma) containing epidermis, hair follicles, and sebaceous glands): 1 person, 100.00%
- Diarrhea: 1 person, 100.00%
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 1 person, 100.00%
Common conditions people have *:
- Osteoporosis (bones weak and more likely to break): 1 person, 100.00%
- Metastases To Bone (cancer spreads to bone): 1 person, 100.00%
* Approximation only. Some reports may have incomplete information.
Do you take Haldol and have Dupuytren's contracture?
Check whether Dupuytren's contracture is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Obayi, O., & Tagbo, N. , "Bilateral Pedal Oedema Associated with Intramuscular Haloperidol–A Rare Observation", International Neuropsychiatric Disease Journal, 2018 Jan .
Related studies
How severe was Dupuytren's contracture and when was it recovered:
Expand to all the drugs that have ingredients of haloperidol:
Alternative drugs to, pros and cons of Haldol:
- Haldol (21,044 reports)
Common Haldol side effects:
- Abdominal pain: 326 reports
- Abdominal pain upper: 164 reports
- Abnormal behavior: 421 reports
- Acute kidney failure: 348 reports
- Adverse drug reaction: 138 reports
- Adverse event: 208 reports
- Aggression: 516 reports
- Agitation (state of anxiety or nervous excitement): 1,097 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 471 reports
- Akathisia (a movement disorder characterized by a feeling of inner restlessness): 230 reports
- Alanine aminotransferase increased: 197 reports
- Altered state of consciousness (altered state of mind): 105 reports
- Anaemia (lack of blood): 372 reports
- Anger: 133 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 245 reports
- Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 152 reports
- Arrhythmias (irregular heartbeat): 430 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 126 reports
- Aspartate aminotransferase increased: 164 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 151 reports
- Back pain: 356 reports
- Balance disorder: 151 reports
- Blood creatine phosphokinase increased: 336 reports
- Blood creatinine increased: 153 reports
- Blood glucose decreased: 121 reports
- Blood glucose increased: 255 reports
- Bone pain: 103 reports
- Bradycardia (abnormally slow heart action): 240 reports
- Breathing difficulty: 732 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 189 reports
- Cardiac arrest: 374 reports
- Cardiac disorder: 169 reports
- Cardiac failure: 137 reports
- Cardiac failure congestive: 163 reports
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 149 reports
- Cataract (clouding of the lens inside the eye): 101 reports
- Catatonia (unresponsive to external stimuli): 106 reports
- Cellulitis (infection under the skin): 118 reports
- Chest pain: 392 reports
- Chills (felling of cold): 127 reports
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 107 reports
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 178 reports
- Completed suicide (act of taking one's own life): 213 reports
- Confusion: 360 reports
- Confusional state: 710 reports
- Consciousness - decreased: 495 reports
- Constipation: 412 reports
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 377 reports
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 119 reports
- Cough: 202 reports
- Death: 641 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 152 reports
- Dehydration (dryness resulting from the removal of water): 371 reports
- Delirium (wild excitement): 328 reports
- Delusion (a false belief or opinion): 280 reports
- Dementia (madness): 119 reports
- Depressed level of consciousness: 264 reports
- Depression: 561 reports
- Diabetes: 1,295 reports
- Diabetes mellitus inadequate control: 229 reports
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 410 reports
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus): 188 reports
- Diarrhea: 471 reports
- Disturbance in attention: 249 reports
- Dizziness: 562 reports
- Drooling (drop saliva uncontrollably from the mouth): 125 reports
- Drowsiness: 1,018 reports
- Drug abuse and dependence: 322 reports
- Drug dependence: 111 reports
- Drug exposure during pregnancy: 113 reports
- Drug hypersensitivity: 352 reports
- Drug ineffective: 750 reports
- Drug toxicity: 113 reports
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 106 reports
- Dry mouth: 202 reports
- Dyskinesia (abnormality or impairment of voluntary movement): 431 reports
- Electrocardiogram qt prolonged: 226 reports
- Electrolyte imbalance: 110 reports
- Emotional disorder: 121 reports
- Emotional distress: 113 reports
- Encephalopathy (functioning of the brain is affected by some agent or condition): 110 reports
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 120 reports
- Erection problems: 157 reports
- Erythema multiforme (a type of hypersensitivity reaction): 185 reports
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck): 541 reports
- Fainting (loss of consciousness and postural tone): 207 reports
- Fall: 761 reports
- Fatigue (feeling of tiredness): 888 reports
- Fever: 883 reports
- Gait disturbance: 367 reports
- Gallstones (stone formation by bile component): 132 reports
- Gamma-glutamyltransferase increased: 116 reports
- Gastritis (inflammation of stomach): 111 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 175 reports
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 127 reports
- General physical health deterioration (weak health status): 399 reports
- Gynecomastia (enlargement of the gland tissue of the male breast): 200 reports
- Haemoglobin decreased: 155 reports
- Hair loss: 126 reports
- Hallucination, auditory (perceiving sounds without auditory stimulus): 364 reports
- Hallucinations (sensations that appear real but are created by your mind): 369 reports
- Hallucination, visual (seeing things that aren't there): 182 reports
- Headache (pain in head): 472 reports
- Head injury: 176 reports
- Heart attack: 226 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 109 reports
- Heart rate increased: 222 reports
- High blood cholesterol: 609 reports
- High blood pressure: 609 reports
- Hospitalisation: 192 reports
- Hyperglycemia (high blood sugar): 286 reports
- Hyperhidrosis (abnormally increased sweating): 217 reports
- Hyperkalemia (damage to or disease of the kidney): 121 reports
- Hyperlipidaemia (presence of excess lipids in the blood): 213 reports
- Hyperprolactinaemia (abnormally high levels of prolactin in the blood): 127 reports
- Hypersensitivity: 214 reports
- Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 120 reports
- Hypoaesthesia (reduced sense of touch or sensation): 162 reports
- Hypoglycemia (low blood sugar): 146 reports
- Hypokalemia (low potassium): 155 reports
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 285 reports
- Hypotension (abnormally low blood pressure): 647 reports
- Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions): 104 reports
- Indigestion: 117 reports
- Infection: 174 reports
- Injury: 216 reports
- Insomnia (sleeplessness): 535 reports
- Intentional overdose: 419 reports
- Intentional self-injury: 582 reports
- International normalised ratio increased: 109 reports
- Intestinal obstruction: 158 reports
- Irritability: 225 reports
- Itching: 157 reports
- Joint pain: 231 reports
- Leukopenia (less number of white blood cells in blood): 192 reports
- Loss of consciousness: 329 reports
- Malaise (a feeling of general discomfort or uneasiness): 427 reports
- Mania (a state of abnormally elevated or irritable mood): 145 reports
- Memory loss: 388 reports
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 215 reports
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 153 reports
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 114 reports
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 112 reports
- Mood swings (an extreme or rapid change in mood): 147 reports
- Movement - uncontrolled or slow: 302 reports
- Muscle aches (muscle pain): 115 reports
- Muscle rigidity (muscle stiffness): 277 reports
- Muscle spasms (muscle contraction): 237 reports
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 238 reports
- Nausea (feeling of having an urge to vomit): 731 reports
- Nausea and vomiting: 608 reports
- Nervousness: 174 reports
- Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 563 reports
- Neuropathy peripheral (surface nerve damage): 243 reports
- Oedema peripheral (superficial swelling): 213 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 101 reports
- Overdose: 604 reports
- Pain: 479 reports
- Pain in extremity: 230 reports
- Pancreatitis (inflammation of pancreas): 391 reports
- Pancreatitis acute (sudden inflammation of pancreas): 123 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 142 reports
- Panic disorder: 160 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 128 reports
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 176 reports
- Parkinson's disease: 320 reports
- Pleural effusion (water on the lungs): 151 reports
- Pneumonia: 581 reports
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 165 reports
- Psychotic disorder: 512 reports
- Pulmonary embolism (blockage of the main artery of the lung): 295 reports
- Pulmonary oedema (fluid accumulation in the lungs): 102 reports
- Rashes (redness): 399 reports
- Renal failure acute (rapid kidney dysfunction): 253 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 190 reports
- Respiratory distress (difficulty in breathing): 148 reports
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 264 reports
- Salivary hypersecretion (excess saliva secretion): 149 reports
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 254 reports
- Sedation: 403 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 114 reports
- Self injurious behavior: 400 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 274 reports
- Septic shock (shock due to blood infection): 113 reports
- Sleep disorder: 136 reports
- Sluggishness (lacking alertness): 165 reports
- Sopor (sleep): 374 reports
- Speech disorder: 258 reports
- Speech impairment (adult) (inability to speak (adult)): 394 reports
- Stress and anxiety: 708 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 175 reports
- Suicidal ideation: 419 reports
- Suicide attempt: 569 reports
- Swallowing difficulty: 480 reports
- Tardive dyskinesia (a disorder that involves involuntary movements): 448 reports
- Thrombocytopenia (decrease of platelets in blood): 381 reports
- Thrombosis (formation of a blood clot inside a blood vessel): 103 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 761 reports
- Type 1 diabetes: 180 reports
- Type 2 diabetes: 978 reports
- Urinary incontinence (inability to control the flow of urine and involuntary urination): 130 reports
- Urinary retention (the inability to completely or partially empty the bladder): 195 reports
- Urinary tract infection: 363 reports
- Vision blurred: 216 reports
- Visual impairment: 123 reports
- Weakness: 684 reports
- Weight decreased: 444 reports
- Weight increased: 833 reports
- Weight loss: 431 reports
- White blood cell count decreased: 118 reports
- White blood cell count increased: 121 reports
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 108 reports
Browse all side effects of Haldol:
a b c d e f g h i j k l m n o p q r s t u v w x y zDupuytren's contracture treatments and more:
- Dupuytren's contracture (2,031 reports)
COVID vaccines that are related to Dupuytren's contracture:
- Dupuytren's contracture in Moderna COVID Vaccine
- Dupuytren's contracture in Pfizer BioNTech Covid Vaccine
- Dupuytren's contracture in Johnson and Johnson Covid Vaccine
Common drugs associated with Dupuytren's contracture:
- Xiaflex: 137 reports
All the drugs that are associated with Dupuytren's contracture:
- Dupuytren's contracture (445 drugs)
Common conditions associated with Dupuytren's contracture:
- Ra: 104 reports
All the conditions that are associated with Dupuytren's contracture:
- Dupuytren's contracture (208 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on haloperidol (the active ingredients of Haldol) and Haldol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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