Haloperidol and Liver disorder - a phase IV clinical study of FDA data

Summary:

Liver disorder is found among people who take Haloperidol, especially for people who are male, 40-49 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Haloperidol and have Liver disorder. It is created by eHealthMe based on reports of 12,935 people who have side effects when taking Haloperidol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Aug, 17, 2022

12,935 people reported to have side effects when taking Haloperidol.
Among them, 57 people (0.44%) have Liver disorder.


What is Haloperidol?

Haloperidol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 11,647 Haloperidol users for its effectiveness, alternative drugs and more.

What is Liver disorder?

Liver disorder (liver diseases) is found to be associated with 2,079 drugs and 1,936 conditions by eHealthMe.

Number of Haloperidol and Liver disorder reports submitted per year:

Could Haloperidol cause Liver disorder?

Time on Haloperidol when people have Liver disorder *:

  • < 1 month: 58.33 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 8.33 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

Gender of people who have Liver disorder when taking Haloperidol *:

  • female: 49.12 %
  • male: 50.88 %

Age of people who have Liver disorder when taking Haloperidol *:

  • 0-1: 4 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6 %
  • 30-39: 8 %
  • 40-49: 36 %
  • 50-59: 16 %
  • 60+: 30 %

Common drugs people take besides Haloperidol *:

  1. Diazepam: 14 people, 24.56%
  2. Clozapine: 10 people, 17.54%
  3. Clozaril: 7 people, 12.28%
  4. Akineton: 5 people, 8.77%
  5. Lorazepam: 5 people, 8.77%
  6. Risperidone: 5 people, 8.77%
  7. Omeprazole: 4 people, 7.02%
  8. Tegretol: 4 people, 7.02%
  9. Disulfiram: 4 people, 7.02%
  10. Abilify: 4 people, 7.02%

Common side effects people have besides Liver disorder *:

  1. C-Reactive Protein Increased: 12 people, 21.05%
  2. Renal Impairment (severely reduced kidney function): 11 people, 19.30%
  3. Malaise (a feeling of general discomfort or uneasiness): 9 people, 15.79%
  4. Blood Creatinine Increased: 9 people, 15.79%
  5. Anaemia (lack of blood): 8 people, 14.04%
  6. Antipsychotic Drug Level Increased: 8 people, 14.04%
  7. Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 14.04%
  8. Fever: 7 people, 12.28%
  9. Pneumonia: 7 people, 12.28%
  10. Aspartate Aminotransferase Increased: 7 people, 12.28%

Common conditions people have *:

  1. Sedation: 5 people, 8.77%
  2. Insomnia (sleeplessness): 4 people, 7.02%
  3. Upper Respiratory Tract Inflammation: 3 people, 5.26%
  4. Salivary Hypersecretion (excess saliva secretion): 3 people, 5.26%
  5. Diabetes: 3 people, 5.26%
  6. Nausea (feeling of having an urge to vomit): 3 people, 5.26%
  7. Uterine Haemorrhage (uterine bleeding): 2 people, 3.51%
  8. Constipation: 2 people, 3.51%
  9. High Blood Cholesterol: 2 people, 3.51%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 3.51%

* Approximation only. Some reports may have incomplete information.

Do you take Haloperidol and have Liver disorder?

Check whether Liver disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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Common drugs associated with Liver disorder:

All the drugs that are associated with Liver disorder:

Common conditions associated with Liver disorder:

All the conditions that are associated with Liver disorder:

How the study uses the data?

The study uses data from the FDA. It is based on haloperidol (the active ingredients of Haloperidol) and Haloperidol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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