Heparin and Dupuytren's contracture - a phase IV clinical study of FDA data

• Heparin (76,043 reports)

• Abasia (inability to walk): 104 reports
• Abdominal discomfort: 287 reports
• Abdominal distension: 721 reports
• Abdominal pain: 1,770 reports
• Abdominal pain lower: 136 reports
• Abdominal pain upper: 811 reports
• Abdominal wall haematoma (abdominal wall blood clotting): 149 reports
• Abortion spontaneous (naturally occurring miscarriage): 128 reports
• Abscess (pus): 123 reports
• Accidental overdose (therapeutic agent): 107 reports
• Acidosis (build-up of carbon dioxide in the blood): 192 reports
• Activated partial thromboplastin time prolonged: 980 reports
• Acute circulatory failure (shock): 169 reports
• Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 122 reports
• Acute generalised exanthematous pustulosis (acute febrile drug eruption): 115 reports
• Acute kidney failure: 4,671 reports
• Acute myocardial infarction (acute heart attack): 688 reports
• Acute pulmonary oedema (sudden deposit of fluid in the lung)): 112 reports
• Acute respiratory failure: 440 reports
• Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 139 reports
• Adverse event: 276 reports
• Agitation (state of anxiety or nervous excitement): 616 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1,086 reports
• Alanine aminotransferase increased: 768 reports
• Altered state of consciousness (altered state of mind): 136 reports
• Anaemia (lack of blood): 2,581 reports
• Anal fissure: 115 reports
• Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation): 111 reports
• Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 624 reports
• Angina unstable (chest pain due to ischemia of the heart muscle- unstable): 182 reports
• Angioedema (rapid swelling of the dermis): 129 reports
• Anhedonia (inability to experience pleasure from activities usually found enjoyable): 1,912 reports
• Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 115 reports
• Anti-erythropoietin antibody positive: 118 reports
• Anuria (failure of the kidneys to produce urine): 167 reports
• Aortic arteriosclerosis (hardening of the aortic arteries): 103 reports
• Aortic thrombosis (formation of a blood clot inside aorta): 101 reports
• Aortic valve incompetence: 112 reports
• Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells): 135 reports
• Aplastic anemia: 173 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 852 reports
• Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 562 reports
• Arrhythmias (irregular heartbeat): 1,355 reports
• Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system): 177 reports
• Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery): 154 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 160 reports
• Ascites (accumulation of fluid in the abdominal cavity): 403 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 160 reports
• Aspartate aminotransferase increased: 735 reports
• Asthma: 242 reports
• Atelectasis (partial or complete collapse of the lung): 503 reports
• Atherosclerosis (disorder of the arteries): 217 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1,744 reports
• Atrial thrombosis (blood clot that develops in an artery): 103 reports
• Atrioventricular block (heart block): 135 reports
• Atrioventricular block complete (heart block complete): 153 reports
• Azotaemia (excess of urea or other nitrogenous compounds in the blood): 104 reports
• Back pain: 1,188 reports
• Bacteraemia (presence of bacteria in the blood): 315 reports
• Bacterial infection: 175 reports
• Balance disorder: 257 reports
• Bleeding disorders: 574 reports
• Bleeding into the skin: 297 reports
• Blindness: 118 reports
• Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 413 reports
• Blood albumin decreased: 298 reports
• Blood alkaline phosphatase increased: 338 reports
• Blood bilirubin increased: 480 reports
• Blood calcium decreased: 171 reports
• Blood creatine phosphokinase increased: 348 reports
• Blood creatinine increased: 1,076 reports
• Blood culture positive: 159 reports
• Blood glucose decreased: 115 reports
• Blood glucose increased: 607 reports
• Blood lactate dehydrogenase increased: 288 reports
• Blood magnesium decreased: 111 reports
• Blood potassium decreased: 250 reports
• Blood pressure systolic increased: 130 reports
• Blood sodium decreased: 119 reports
• Blood urea increased: 565 reports
• Blood urine present: 117 reports
• Body temperature increased: 173 reports
• Bone density decreased: 104 reports
• Bone disorder: 262 reports
• Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 184 reports
• Bone marrow failure: 197 reports
• Bone pain: 242 reports
• Bradycardia (abnormally slow heart action): 908 reports
• Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull): 193 reports
• Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 250 reports
• Breathing difficulty: 3,285 reports
• Breathing - slowed or stopped: 256 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 510 reports
• Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 172 reports
• Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle): 122 reports
• Burning sensation: 290 reports
• Candidiasis (candidiasis or thrush is a fungal infection): 121 reports
• Cardiac arrest: 1,891 reports
• Cardiac disorder: 537 reports
• Cardiac failure: 1,116 reports
• Cardiac failure acute: 106 reports
• Cardiac failure congestive: 1,090 reports
• Cardiac murmur (an heart sound in valve abnormality): 123 reports
• Cardiac tamponade (fluid accumulates in heart covering): 512 reports
• Cardioactive drug level increased: 121 reports
• Cardiogenic shock (inadequate circulation of blood): 890 reports
• Cardiomyopathy (weakening of the heart muscle): 188 reports
• Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 807 reports
• Cataract (clouding of the lens inside the eye): 189 reports
• Catheter related complication: 102 reports
• Catheter site haemorrhage (bleeding at catheter site): 225 reports
• Cellulitis (infection under the skin): 616 reports
• Cerebral haematoma (collection of blood in brain): 129 reports
• Cerebral haemorrhage (bleeding within the brain): 1,080 reports
• Cerebral infarction (less blood supply to brain resulting tissue damage): 663 reports
• Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand): 154 reports
• Chest pain: 2,614 reports
• Chills (felling of cold): 1,039 reports
• Cholecystitis (infection of gallbladder): 135 reports
• Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 187 reports
• Chronic kidney disease: 643 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 409 reports
• Circulatory collapse: 264 reports
• Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 167 reports
• Coagulation time prolonged: 160 reports
• Coagulation time shortened: 110 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 119 reports
• Colitis (inflammation of colon): 261 reports
• Colonic polyp (extra part of colon tissue grow in intestine): 197 reports
• Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels): 195 reports
• Confusion: 392 reports
• Confusional state: 940 reports
• Conjunctivitis (pink eye): 103 reports
• Consciousness - decreased: 511 reports
• Constipation: 1,001 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 432 reports
• Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 143 reports
• Coronary artery occlusion (complete obstruction of blood flow in a coronary artery): 295 reports
• Coronary artery stenosis (narrowing of coronary artery): 199 reports
• Coronary artery thrombosis (clot formation in coronary artery): 200 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 560 reports
• Cough: 1,115 reports
• Coughing up blood: 679 reports
• C-reactive protein increased: 361 reports
• Cuts and puncture wounds: 114 reports
• Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 101 reports
• Cytomegalovirus infection: 202 reports
• Death: 3,372 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1,662 reports
• Deformity (disfigurement): 174 reports
• Dehydration (dryness resulting from the removal of water): 914 reports
• Delirium (wild excitement): 273 reports
• Depressed level of consciousness: 546 reports
• Depression: 1,539 reports
• Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 319 reports
• Device occlusion: 111 reports
• Device related infection: 290 reports
• Diabetes: 369 reports
• Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 124 reports
• Diarrhea: 2,430 reports
• Disability: 246 reports
• Discomfort: 165 reports
• Disease progression: 412 reports
• Disease recurrence: 126 reports
• Disseminated intravascular coagulation (systemic activation of blood coagulation): 759 reports
• Disturbance in attention: 132 reports
• Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 133 reports
• Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 213 reports
• Dizziness: 1,566 reports
• Drowsiness: 582 reports
• Drug administration error: 200 reports
• Drug effect decreased: 310 reports
• Drug exposure during pregnancy: 314 reports
• Drug hypersensitivity: 1,025 reports
• Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications): 122 reports
• Drug ineffective: 2,548 reports
• Drug intolerance (drug sensitivity): 105 reports
• Drug maladministration: 154 reports
• Drug resistance (reduction in effectiveness of a drug): 126 reports
• Drug toxicity: 143 reports
• Dry mouth: 161 reports
• Dry skin: 189 reports
• Dyskinesia (abnormality or impairment of voluntary movement): 154 reports
• Dyspnea exertional: 267 reports
• Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 295 reports
• Ejection fraction decreased (systolic heart failure): 265 reports
• Electrocardiogram qt prolonged: 285 reports
• Electrocardiogram st segment elevation: 243 reports
• Electrolyte imbalance: 137 reports
• Embolic stroke (stroke due to obstruction due to an embolus): 110 reports
• Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 235 reports
• Emotional disorder: 138 reports
• Emotional distress: 2,452 reports
• Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 108 reports
• Encephalopathy (functioning of the brain is affected by some agent or condition): 389 reports
• Endocarditis (inflammation in heart muscle): 134 reports
• Enlarged heart: 368 reports
• Enterococcal infection: 172 reports
• Eosinophilia (eosinophil count in the peripheral blood exceeds): 193 reports
• Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs): 147 reports
• Erythema multiforme (a type of hypersensitivity reaction): 671 reports
• Escherichia infection (bacterial infection by escherichia coli): 118 reports
• Exostosis (formation of new bone on the surface of a bone): 135 reports
• Exposed bone in jaw: 113 reports
• Extradural haematoma (traumatic brain injury-collection of blood in the 'potential' space between the skull and the outer protective): 169 reports
• Face oedema (swelling of face): 158 reports
• Faeces discolored: 125 reports
• Fainting (loss of consciousness and postural tone): 673 reports
• Fall: 1,337 reports
• Fatigue (feeling of tiredness): 2,507 reports
• Fear: 2,323 reports
• Febrile neutropenia (fever with reduced white blood cells): 823 reports
• Feeling cold: 109 reports
• Feeling hot: 229 reports
• Fever: 3,489 reports
• Fibrosis (formation of excess fibrous connective tissue in an organ or tissue): 101 reports
• Flank pain (a distressing sensation experienced around the lower back and the upper abdomen): 134 reports
• Flatulence (flatus expelled through the anus): 121 reports
• Fluid overload (too much fluid in the blood): 470 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 206 reports
• Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 621 reports
• Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy): 125 reports
• Fungal infection: 234 reports
• Gait disturbance: 484 reports
• Gallstones (stone formation by bile component): 389 reports
• Gamma-glutamyltransferase increased: 227 reports
• Gangrene (body tissue dies): 263 reports
• Gastric haemorrhage (bleeding stomach): 143 reports
• Gastric ulcer (stomach ulcer): 371 reports
• Gastritis (inflammation of stomach): 319 reports
• Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection): 187 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 472 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 244 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 1,742 reports
• Generalised oedema (swelling all over the body): 157 reports
• General physical health deterioration (weak health status): 847 reports
• Gingival bleeding (bleeding gums): 211 reports
• Gout (uric acid crystals building up in the body): 102 reports
• Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 111 reports
• Grand mal convulsion (a type of generalized seizure that affects the entire brain): 128 reports
• Groin pain: 120 reports
• Haematemesis (vomiting of blood): 570 reports
• Haematochezia (passage of stools containing blood): 303 reports
• Haematocrit decreased: 897 reports
• Haematoma (collection of blood outside the blood vessels): 1,351 reports
• Haematuria (presence of blood in urine): 667 reports
• Haematuria present (presence of blood in urine due to trauma): 139 reports
• Haemodynamic instability (disturbances in the blood movement in our body): 264 reports
• Haemoglobin decreased: 2,311 reports
• Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 167 reports
• Haemolytic anaemia (anaemia due to haemolysis): 116 reports
• Haemorrhage (bleeding): 2,814 reports
• Haemorrhage intracranial (bleeding within the skull): 785 reports
• Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain): 556 reports
• Haemorrhoids (a swollen vein or group of veins in the region of the anus): 310 reports
• Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest)): 197 reports
• Hair loss: 355 reports
• Hallucinations (sensations that appear real but are created by your mind): 193 reports
• Headache (pain in head): 2,262 reports
• Head injury: 625 reports
• Hearing loss: 122 reports
• Heart attack: 1,913 reports
• Heart disease: 196 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 438 reports
• Heart rate decreased: 200 reports
• Heart rate increased: 648 reports
• Heart rate irregular: 152 reports
• Hemiparesis (weakness on one side of the body): 359 reports
• Hemiplegia (paralysis of one side of the body): 202 reports
• Heparin-induced thrombocytopenia: 3,283 reports
• Hepatic enzyme increased: 343 reports
• Hepatic failure (liver failure): 502 reports
• Hepatic steatosis (fatty liver disease): 185 reports
• Hepatitis (inflammation of the liver): 162 reports
• Hepatomegaly (abnormal enlargement of the liver): 146 reports
• Hepatotoxicity (chemical-driven liver damage): 172 reports
• Hereditary angioedema (recurrent episodes of severe swelling): 372 reports
• Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 124 reports
• Herpes zoster: 275 reports
• Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 203 reports
• High blood cholesterol: 358 reports
• High blood pressure: 1,815 reports
• Hip fracture: 103 reports
• Hoarseness or changing voice: 162 reports
• Hospitalisation: 199 reports
• Hot flush (sudden feelings of heat): 119 reports
• Hydrocephalus (water on the brain): 140 reports
• Hyperbilirubinaemia (excess of bilirubin in the blood): 177 reports
• Hypercalcaemia (elevated calcium (ca+) level in the blood): 109 reports
• Hyperglycemia (high blood sugar): 436 reports
• Hyperhidrosis (abnormally increased sweating): 755 reports
• Hyperkalemia (damage to or disease of the kidney): 815 reports
• Hyperlipidaemia (presence of excess lipids in the blood): 272 reports
• Hypernatraemia (an abnormally high plasma concentration of sodium ions): 141 reports
• Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 124 reports
• Hypersensitivity: 715 reports
• Hyperuricaemia (level of uric acid in the blood that is abnormally high): 101 reports
• Hypoaesthesia (reduced sense of touch or sensation): 745 reports
• Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 161 reports
• Hypocalcaemia (levels of calcium in blood serum are abnormally low): 222 reports
• Hypoglycemia (low blood sugar): 287 reports
• Hypokalemia (low potassium): 725 reports
• Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 177 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 529 reports
• Hypophagia (reduced food intake): 198 reports
• Hypopnea: 126 reports
• Hypotension (abnormally low blood pressure): 5,187 reports
• Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions): 106 reports
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 224 reports
• Hypovolaemia (a decreased volume of circulating blood in the body): 176 reports
• Hypovolaemic shock (shock caused by severe blood or fluid loss): 127 reports
• Idiopathic pulmonary fibrosis (chronic lung disease): 117 reports
• Impaired healing: 225 reports
• Incision site pain: 112 reports
• Indigestion: 272 reports
• Infection: 851 reports
• Inflammation: 196 reports
• Influenza like illness: 179 reports
• Infusion related reaction: 639 reports
• Injection site erythema (redness at injection site): 108 reports
• Injection site haemorrhage (bleeding from injection site): 305 reports
• Injection site pain: 170 reports
• Injection site reaction: 107 reports
• Injury: 3,045 reports
• Insomnia (sleeplessness): 598 reports
• International normalised ratio decreased: 150 reports
• International normalised ratio increased: 671 reports
• Interstitial lung disease: 328 reports
• Interstitial nephritis (inflammation of the kidney): 133 reports
• Intervertebral disc degeneration (spinal disc degeneration): 221 reports
• Intervertebral disc protrusion (spinal disc protrusion): 158 reports
• Intestinal ischaemia (decreased supply of oxygenated blood to the intestines): 182 reports
• Intestinal obstruction: 369 reports
• Intra-abdominal haemorrhage (intra-abdominal bleeding): 152 reports
• Intracardiac thrombus (presence of a circumscribed mass with heart wall): 207 reports
• Intraventricular haemorrhage (intraventricular bleeding): 172 reports
• Iron deficiency anaemia: 152 reports
• Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery): 162 reports
• Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells): 103 reports
• Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain): 364 reports
• Itching: 1,046 reports
• Jaundice - yellow skin (a yellowish pigmentation of the skin): 219 reports
• Joint pain: 872 reports
• Joint range of motion decreased (disease of joint movement): 109 reports
• Joint swelling: 201 reports
• Jugular vein thrombosis (clot in jugular vein): 118 reports
• Kidney stones: 182 reports
• Klebsiella infection: 109 reports
• Lactic acidosis (low ph in body tissues): 189 reports
• Left ventricular dysfunction: 159 reports
• Left ventricular failure (left ventricle fails to contract forcefully): 199 reports
• Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 101 reports
• Leukocytosis (increased white blood cells): 429 reports
• Leukopenia (less number of white blood cells in blood): 433 reports
• Limb injury: 114 reports
• Liver disorder (liver diseases): 248 reports
• Liver injury: 106 reports
• Loss of consciousness: 736 reports
• Low birth weight baby: 260 reports
• Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding): 121 reports
• Lower respiratory tract infection: 119 reports
• Low tissue oxygen: 630 reports
• Lung disorder (lung disease): 309 reports
• Lung infection: 203 reports
• Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 298 reports
• Lung neoplasm (tumour of lung): 129 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 260 reports
• Lymphocyte count decreased: 365 reports
• Malaise (a feeling of general discomfort or uneasiness): 1,058 reports
• Malignant neoplasm progression (cancer tumour came back): 351 reports
• Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 235 reports
• Maternal exposure during pregnancy (use of substance during pregnancy): 724 reports
• Melaena (the passage of black, tarry stools): 374 reports
• Memory loss: 421 reports
• Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 200 reports
• Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 133 reports
• Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 544 reports
• Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 463 reports
• Metastases to bone (cancer spreads to bone): 230 reports
• Metastases to liver (cancer spreads to liver): 107 reports
• Metastases to lung (cancer spreads to lung): 118 reports
• Migraine (headache): 275 reports
• Mitral valve incompetence (inefficient heart valve): 350 reports
• Mobility decreased (ability to move is reduced): 194 reports
• Mouth haemorrhage (bleeding from mouth): 220 reports
• Mouth ulcers: 150 reports
• Mucosal inflammation (infection of mucous membrane): 229 reports
• Multi-organ failure (multisystem organ failure): 2,265 reports
• Multiple myeloma (cancer of the plasma cells): 283 reports
• Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 102 reports
• Muscle aches (muscle pain): 373 reports
• Muscle function loss: 133 reports
• Muscle haemorrhage (bleeding in muscle): 203 reports
• Muscle spasms (muscle contraction): 410 reports
• Muscle twitching: 172 reports
• Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 130 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 275 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 173 reports
• Mydriasis (a dilation of the pupil): 122 reports
• Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 266 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 175 reports
• Nasopharyngitis (inflammation of the nasopharynx): 349 reports
• Nausea (feeling of having an urge to vomit): 3,732 reports
• Nausea and vomiting: 2,695 reports
• Neck pain: 261 reports
• Necrosis (the death of body tissue): 176 reports
• Neoplasm malignant (cancer tumour): 194 reports
• Neoplasm progression (growth of tumour): 129 reports
• Nephrogenic anaemia (anaemia due to kidney disease): 278 reports
• Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 175 reports
• Nervousness: 267 reports
• Nervous system disorder (a general class of medical conditions affecting the nervous system): 216 reports
• Neuralgia (pain in one or more nerves): 116 reports
• Neuropathy peripheral (surface nerve damage): 504 reports
• Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 103 reports
• Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 205 reports
• Neutrophil count increased (excess than normal number of neutrophil a type of blood cell): 229 reports
• Night sweats (sweating in night): 129 reports
• Nosebleed (bleeding from nose): 822 reports
• Oedema (fluid collection in tissue): 532 reports
• Oedema peripheral (superficial swelling): 1,289 reports
• Oesophagitis (inflammation of oesophagus): 149 reports
• Oral candidiasis (fungal infection of mouth): 138 reports
• Oral pain: 152 reports
• Organ failure: 244 reports
• Oropharyngeal pain: 231 reports
• Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 118 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 371 reports
• Osteomyelitis (infection of bone): 381 reports
• Osteonecrosis of jaw (death of bone of jaw): 434 reports
• Osteopenia (a condition where bone mineral density is lower than normal): 198 reports
• Osteoporosis (bones weak and more likely to break): 215 reports
• Otitis (ear infection): 154 reports
• Overdose: 426 reports
• Oxygen saturation decreased: 607 reports
• Pain: 4,956 reports
• Pain in extremity: 1,070 reports
• Pain in jaw: 271 reports
• Pain in limb: 110 reports
• Paleness (unusual lightness of skin colour): 285 reports
• Pancreatitis (inflammation of pancreas): 307 reports
• Pancreatitis acute (sudden inflammation of pancreas): 142 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 707 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 526 reports
• Paraplegia (paralysis of the legs and lower body): 120 reports
• Paroxysmal supraventricular tachycardia: 237 reports
• Pathological fracture (broken bone caused by disease): 137 reports
• Pericardial effusion (fluid around the heart): 482 reports
• Pericardial haemorrhage (bleeding into the heart): 182 reports
• Peripheral coldness: 136 reports
• Peripheral ischaemia (impaired circulation to an extremity): 290 reports
• Peripheral swelling: 326 reports
• Peripheral vascular disorder: 146 reports
• Peritoneal haemorrhage (peritoneal bleeding): 106 reports
• Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 315 reports
• Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial): 161 reports
• Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 201 reports
• Pharyngitis (inflammation of the pharynx, causing a sore throat): 110 reports
• Platelet count increased: 108 reports
• Pleural effusion (water on the lungs): 1,248 reports
• Pneumonia: 2,613 reports
• Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 346 reports
• Pneumonia bacterial (pneumonia associated with bacterial infection): 112 reports
• Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 223 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 169 reports
• Post procedural complication: 460 reports
• Post procedural haematoma (post procedural clotting of blood): 101 reports
• Post procedural haemorrhage (post procedural bleeding): 493 reports
• Premature baby: 606 reports
• Premature delivery: 328 reports
• Pressure ulcer: 159 reports
• Presyncope: 124 reports
• Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 136 reports
• Procedural complication: 253 reports
• Procedural pain: 104 reports
• Productive cough: 266 reports
• Protein - urine: 159 reports
• Protein urine present: 123 reports
• Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 215 reports
• Psychiatric symptom: 101 reports
• Psychological trauma: 113 reports
• Pulmonary alveolar haemorrhage (acute bleeding): 232 reports
• Pulmonary congestion (congestion in the lungs): 224 reports
• Pulmonary embolism (blockage of the main artery of the lung): 2,126 reports
• Pulmonary haemorrhage (acute bleeding from the lung): 471 reports
• Pulmonary hypertension (increase in blood pressure in the lung artery): 390 reports
• Pulmonary oedema (fluid accumulation in the lungs): 917 reports
• Pulse absent: 213 reports
• Pulseless electrical activity: 149 reports
• Purpura (purplish discoloration of the skin): 157 reports
• Rales (an abnormal respiratory sound characterized by fine crackles): 138 reports
• Rash erythematous (redness of the skin): 267 reports
• Rashes (redness): 2,158 reports
• Rash macular (small, flat red spots): 110 reports
• Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 246 reports
• Rash pruritic (redness with itching): 150 reports
• Rectal haemorrhage (bleeding from anus): 472 reports
• Red blood cell count decreased: 264 reports
• Renal cyst (kidney cyst): 177 reports
• Renal disorder (kidney disease): 198 reports
• Renal failure acute (rapid kidney dysfunction): 1,798 reports
• Renal failure chronic (long lasting kidney dysfunction): 395 reports
• Renal impairment (severely reduced kidney function): 2,516 reports
• Renal injury (kidney injury): 2,198 reports
• Renal tubular necrosis (death of kidney tubules): 234 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 1,795 reports
• Respiratory disorder (respiratory disease): 252 reports
• Respiratory distress (difficulty in breathing): 624 reports
• Respiratory rate increased (excess breathing rate/min): 104 reports
• Respiratory tract infection: 169 reports
• Retching (strong involuntary effort to vomit): 134 reports
• Retroperitoneal haematoma (blood clot between the peritoneum and the posterior abdominal wall): 331 reports
• Retroperitoneal haemorrhage (bleeding between the peritoneum and the posterior abdominal wall): 669 reports
• Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 408 reports
• Rib fracture: 138 reports
• Right ventricular failure (right half of the heart fails to work): 306 reports
• Scar: 141 reports
• Sedation: 164 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 272 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 2,280 reports
• Septic shock (shock due to blood infection): 972 reports
• Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 519 reports
• Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding): 360 reports
• Sinus bradycardia (an unusually slow heartbeat due to heart disease): 135 reports
• Sinus disorder (disease of sinus): 122 reports
• Sinusitis (inflammation of sinus): 656 reports
• Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 335 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 427 reports
• Skin discoloration: 281 reports
• Skin discoloration - bluish (bluish colour of skin): 243 reports
• Skin disorder (skin disease): 170 reports
• Skin exfoliation (removal of the oldest dead skin cells): 164 reports
• Skin hypertrophy (skin cells enlarges): 107 reports
• Skin induration (an abnormally hard spot or area on the skin): 122 reports
• Skin necrosis (skin damage): 214 reports
• Skin ulcer: 253 reports
• Sleep apnea syndrome: 189 reports
• Sleep disorder: 139 reports
• Small intestinal obstruction (blockage in small intestine): 140 reports
• Speech disorder: 206 reports
• Speech impairment (adult) (inability to speak (adult)): 587 reports
• Spinal cord compression: 132 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 257 reports
• Splenomegaly (enlargement of spleen): 130 reports
• Stable angina (a constant chest pain): 403 reports
• Staphylococcal bacteraemia (a bacterial infection of blood): 103 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 507 reports
• Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria): 134 reports
• Stomatitis (inflammation of mucous membrane of mouth): 306 reports
• Stress and anxiety: 3,789 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1,690 reports
• Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain): 399 reports
• Subdural haematoma (blood collects between the skull and the surface of the brain): 372 reports
• Surgery: 168 reports
• Swallowing difficulty: 611 reports
• Swelling: 514 reports
• Swelling face: 225 reports
• Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection): 118 reports
• Tachypnea: 307 reports
• Taste - impaired: 148 reports
• Tenderness (pain or discomfort when an affected area is touched): 137 reports
• The flu (the flu is caused by an influenza virus): 251 reports
• Therapeutic response decreased (less preventive response): 235 reports
• Thirst: 113 reports
• Thrombocytopenia (decrease of platelets in blood): 6,217 reports
• Thromboembolism (obstruction of artery by blood clot): 116 reports
• Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 172 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 1,419 reports
• Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 194 reports
• Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body): 127 reports
• Tooth abscess (pus formation in tooth): 238 reports
• Toothaches (tooth pain): 158 reports
• Tooth disorder (tooth disease): 113 reports
• Tooth extraction: 157 reports
• Tooth loss: 185 reports
• Torsade de pointes (a abnormal heart rate with abnormal beating pattern): 169 reports
• Transaminases increased: 196 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 301 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 566 reports
• Tricuspid valve incompetence (inefficient heart valve): 247 reports
• Troponin increased: 126 reports
• Tumor: 150 reports
• Tumor lysis syndrome: 117 reports
• Type 2 diabetes: 112 reports
• Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter): 137 reports
• Unresponsive to stimuli: 631 reports
• Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding): 296 reports
• Upper respiratory tract infection: 439 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 232 reports
• Urinary retention (the inability to completely or partially empty the bladder): 206 reports
• Urinary tract infection: 1,558 reports
• Urination - painful: 238 reports
• Urine output decreased: 147 reports
• Urine output - decreased: 303 reports
• Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 122 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 447 reports
• Vaginal bleeding: 170 reports
• Varicose vein (veins that have become enlarged and tortuous): 116 reports
• Vascular pseudoaneurysm (leakage of arterial blood from an artery into the surrounding tissue with a continuing communication between the originating artery and the resultant adjacent cavity): 232 reports
• Vasculitis (inflammation of a blood vessel or blood vessels): 122 reports
• Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart): 122 reports
• Venoocclusive disease (small veins in the liver are obstructed): 111 reports
• Venous thrombosis (blood clot (thrombus) that forms within a vein): 193 reports
• Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb): 140 reports
• Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat): 114 reports
• Ventricular extrasystoles (premature cardiac contraction): 248 reports
• Ventricular fibrillation (abnormally irregular heart rhythm): 597 reports
• Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 692 reports
• Viral infection: 146 reports
• Vision blurred: 375 reports
• Visual impairment: 209 reports
• Weakness: 2,249 reports
• Weight decreased: 806 reports
• Weight increased: 441 reports
• Weight loss: 125 reports
• Wheezing (a high-pitched whistling sound made while you breath): 246 reports
• White blood cell count decreased: 555 reports
• White blood cell count increased: 545 reports
• Wound: 122 reports

• Dupuytren's contracture (2,031 reports)

All the drugs that are associated with Dupuytren's contracture:

• Dupuytren's contracture (445 drugs)

All the conditions that are associated with Dupuytren's contracture:

• Dupuytren's contracture (208 conditions)

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