Humira and Gastrointestinal inflammation - a phase IV clinical study of FDA data

Summary:

Gastrointestinal inflammation is found among people who take Humira, especially for people who are female, 30-39 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Humira and have Gastrointestinal inflammation. It is created by eHealthMe based on reports of 606,284 people who have side effects when taking Humira from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 10, 2022

606,284 people reported to have side effects when taking Humira.
Among them, 2,705 people (0.45%) have Gastrointestinal inflammation.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 608,927 Humira users for its effectiveness, alternative drugs and more.

What is Gastrointestinal inflammation?

Gastrointestinal inflammation (inflammation of stomach and intestine) is found to be associated with 741 drugs and 477 conditions by eHealthMe.

Number of Humira and Gastrointestinal inflammation reports submitted per year:

Could Humira cause Gastrointestinal inflammation?

* Approximation only. Some reports may have incomplete information.

Do you take Humira and have Gastrointestinal inflammation?

Check whether Gastrointestinal inflammation is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel SY, Booth C, Runz H, "Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn9s disease", Gut, 2016 Mar .

Related studies

Alternative drugs to, pros and cons of Humira:

Humira (608,927 reports)

Gastrointestinal inflammation treatments and more:

Gastrointestinal inflammation (6,885 reports)

COVID vaccines that are related to Gastrointestinal inflammation:

How severe was Gastrointestinal inflammation and when was it recovered:

Gastrointestinal inflammation in Humira

Expand to all the drugs that have ingredients of adalimumab:

Gastrointestinal inflammation and drugs with ingredients of adalimumab

Common drugs associated with Gastrointestinal inflammation:

All the drugs that are associated with Gastrointestinal inflammation:

Gastrointestinal inflammation (741 drugs)

Common conditions associated with Gastrointestinal inflammation:

Ankylosing spondylitis: 101 reports
Blood pressure increased: 331 reports
Crohn's disease: 2,655 reports
Crohns disease: 2,655 reports
Gastroesophageal reflux disease: 144 reports
Hbp: 350 reports
High blood cholesterol: 123 reports
High blood pressure: 350 reports
Hyperlipidemia: 123 reports
Hypertension: 350 reports
Ileitis: 2,655 reports
Inflammatory bowel disease - crohn's disease: 2,655 reports
Lipoprotein test: 123 reports
Multiple sclerosis: 115 reports
Pain: 224 reports
Pain management: 224 reports
Rheumatoid arthritis: 327 reports
Stress and anxiety: 108 reports
Ulcerative colitis: 527 reports

All the conditions that are associated with Gastrointestinal inflammation:

Gastrointestinal inflammation (477 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.