Humira and Intervertebral disc degeneration - a phase IV clinical study of FDA data
Summary:
We study 647,817 people who have side effects when taking Humira. Intervertebral disc degeneration is found, especially among people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take Methotrexate and have Psoriatic arthropathy.
The phase IV clinical study analyzes which people take Humira and have Intervertebral disc degeneration. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
647,817 people reported to have side effects when taking Humira.
Among them, 1,211 people (0.19%) have Intervertebral disc degeneration.
What is Humira?
Humira has active ingredients of adalimumab. It is used in rheumatoid arthritis. Currently, eHealthMe is studying from 738,352 Humira users.
What is Intervertebral disc degeneration?
Intervertebral disc degeneration (spinal disc degeneration) is found to be associated with 2,386 drugs and 1,428 conditions by eHealthMe. Currently, we are studying 19,356 people who have Intervertebral disc degeneration.
Number of Humira and Intervertebral disc degeneration reports submitted per year:
Time on Humira when people have Intervertebral disc degeneration *:
Gender of people who have Intervertebral disc degeneration when taking Humira*:
Age of people who have Intervertebral disc degeneration when taking Humira *:
Common drugs people take besides Humira *:
Common side effects people have besides Intervertebral disc degeneration *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Humira and have Intervertebral disc degeneration?
Check whether Intervertebral disc degeneration is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
Related studies
Humira side effects by duration, gender and age:
- Humira side effects (738,352 reports)
Intervertebral disc degeneration treatments and more:
- Intervertebral disc degeneration (19,356 reports)
Common drugs associated with Intervertebral disc degeneration:
- Fosamax: 3,044 reports
- Zometa: 2,145 reports
- Prednisone: 1,645 reports
- Aspirin: 1,416 reports
- Aredia: 1,331 reports
- Humira: 1,211 reports
- Gabapentin: 1,097 reports
- Methotrexate: 1,079 reports
- Vioxx: 1,074 reports
- Celebrex: 976 reports
All the drugs that are associated with Intervertebral disc degeneration:
- Intervertebral disc degeneration (2,386 drugs)
Common conditions associated with Intervertebral disc degeneration:
- Osteoporosis: 2,563 reports
- Rheumatoid arthritis: 1,474 reports
- Pain: 1,188 reports
- High blood pressure: 964 reports
- Multiple sclerosis: 944 reports
All the conditions that are associated with Intervertebral disc degeneration:
- Intervertebral disc degeneration (1,428 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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