Humira and Obstruction - a phase IV clinical study of FDA data

Summary:

Obstruction is found among people who take Humira, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Humira and have Obstruction. It is created by eHealthMe based on reports of 647,817 people who have side effects when taking Humira from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 29, 2023

647,817 people reported to have side effects when taking Humira.
Among them, 785 people (0.12%) have Obstruction.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 650,600 Humira users for its effectiveness, alternative drugs and more.

What is Obstruction?

Obstruction is found to be associated with 1,222 drugs and 599 conditions by eHealthMe.

Number of Humira and Obstruction reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Humira and have Obstruction?

Check whether Obstruction is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .

Related studies

How severe was Obstruction and when was it recovered:

Obstruction in Humira

Expand to all the drugs that have ingredients of adalimumab:

Obstruction and drugs with ingredients of adalimumab

Alternative drugs to, pros and cons of Humira:

Humira (650,600 reports)

Common Humira side effects:

Drug ineffective: 93,489 reports
Joint pain: 47,464 reports
Pain: 47,288 reports
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 39,149 reports
Fatigue (feeling of tiredness): 38,407 reports
Rashes (redness): 32,791 reports
Diarrhea: 27,396 reports

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Obstruction treatments and more:

Obstruction (3,464 reports)

COVID vaccines that are related to Obstruction:

Common drugs associated with Obstruction:

All the drugs that are associated with Obstruction:

Obstruction (1,222 drugs)

Common conditions associated with Obstruction:

Crohn's disease: 922 reports
Asthma: 228 reports
Rheumatoid arthritis: 108 reports

All the conditions that are associated with Obstruction:

Obstruction (599 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.