Humira and Seizures - a phase IV clinical study of FDA data
Summary:
Seizures is found among people who take Humira, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Humira and have Seizures. It is created by eHealthMe based on reports of 647,817 people who have side effects when taking Humira from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
647,817 people reported to have side effects when taking Humira.
Among them, 2,379 people (0.37%) have Seizures.
What is Humira?
Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 650,663 Humira users for its effectiveness, alternative drugs and more.
What is Seizures?
Seizures (abnormal excessive or synchronous neuronal activity in the brain) is found to be associated with 2,861 drugs and 2,139 conditions by eHealthMe.
Number of Humira and Seizures reports submitted per year:

Time on Humira when people have Seizures *:
Gender of people who have Seizures when taking Humira*:
Age of people who have Seizures when taking Humira *:
Common drugs people take besides Humira *:
Common side effects people have besides Seizures *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Humira and have Seizures?
Check whether Seizures is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
Related studies
How severe was Seizures and when was it recovered:
Expand to all the drugs that have ingredients of adalimumab:
- Seizures and drugs with ingredients of adalimumab (2,410 reports)
Alternative drugs to, pros and cons of Humira:
- Humira (650,663 reports)
Common Humira side effects:
- Drug ineffective: 93,489 reports
- Joint pain: 47,464 reports
- Pain: 47,288 reports
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 39,149 reports
- Fatigue (feeling of tiredness): 38,407 reports
- Rashes (redness): 32,791 reports
- Diarrhea: 27,396 reports
Browse all side effects of Humira:
a b c d e f g h i j k l m n o p q r s t u v w x y zSeizures treatments and more:
- Seizures (122,961 reports)
COVID vaccines that are related to Seizures:
- Seizures in Moderna COVID Vaccine
- Seizures in Pfizer BioNTech Covid Vaccine
- Seizures in Johnson and Johnson Covid Vaccine
Common drugs associated with Seizures:
- Levetiracetam: 7,432 reports
- Keppra: 6,563 reports
- Epidiolex: 4,121 reports
- Lamotrigine: 3,463 reports
- Vimpat: 3,176 reports
- Lamictal: 2,547 reports
- Gabapentin: 2,503 reports
- Lacosamide: 2,437 reports
- Clonazepam: 2,405 reports
- Humira: 2,379 reports
All the drugs that are associated with Seizures:
- Seizures (2,861 drugs)
Common conditions associated with Seizures:
- Epilepsy: 9,254 reports
- Multiple sclerosis: 6,059 reports
- Depression: 2,604 reports
- Pain: 2,466 reports
- High blood pressure: 1,990 reports
All the conditions that are associated with Seizures:
- Seizures (2,139 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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