Humira and Stress urinary incontinence - a phase IV clinical study of FDA data


We study 735,454 people who have side effects when taking Humira. Stress urinary incontinence is found, especially among people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Methotrexate and have Psoriasis.

The phase IV clinical study analyzes which people take Humira and have Stress urinary incontinence. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

On Sep, 25, 2023

735,454 people reported to have side effects when taking Humira.
Among them, 55 people (0.01%) have Stress urinary incontinence.

What is Humira?

Humira has active ingredients of adalimumab. It is used in rheumatoid arthritis. Currently, eHealthMe is studying from 738,352 Humira users.

What is Stress urinary incontinence?

Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise) is found to be associated with 853 drugs and 379 conditions by eHealthMe. Currently, we are studying 2,412 people who have Stress urinary incontinence.

Number of Humira and Stress urinary incontinence reports submitted per year:

Could Humira cause Stress urinary incontinence?

Time on Humira when people have Stress urinary incontinence *:

  • < 1 month: 7.69 %
  • 1 - 6 months: 26.92 %
  • 6 - 12 months: 11.54 %
  • 1 - 2 years: 11.54 %
  • 2 - 5 years: 23.08 %
  • 5 - 10 years: 15.38 %
  • 10+ years: 3.85 %

Gender of people who have Stress urinary incontinence when taking Humira *:

  • female: 98.15 %
  • male: 1.85 %

Age of people who have Stress urinary incontinence when taking Humira *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.33 %
  • 30-39: 6.67 %
  • 40-49: 13.33 %
  • 50-59: 16.67 %
  • 60+: 60.0 %

Common drugs people take besides Humira *:

  1. Methotrexate: 10 people, 18.18%
  2. Amlodipine: 4 people, 7.27%
  3. Zestril: 4 people, 7.27%
  4. Magnesium: 4 people, 7.27%
  5. Fosamax: 4 people, 7.27%
  6. Folic Acid: 4 people, 7.27%
  7. Omeprazole: 3 people, 5.45%
  8. Vitamin D3: 3 people, 5.45%
  9. Nexium: 3 people, 5.45%
  10. Diclofenac Sodium: 2 people, 3.64%

Common side effects people have besides Stress urinary incontinence *:

  1. Urinary Tract Infection: 10 people, 18.18%
  2. Pain: 7 people, 12.73%
  3. Diarrhea: 6 people, 10.91%
  4. Injection Site Pain: 6 people, 10.91%
  5. Malaise (a feeling of general discomfort or uneasiness): 6 people, 10.91%
  6. Breathing Difficulty: 6 people, 10.91%
  7. Burning Sensation: 5 people, 9.09%
  8. Fatigue (feeling of tiredness): 5 people, 9.09%
  9. Depression: 5 people, 9.09%
  10. Cough: 5 people, 9.09%

Common conditions people have *:

  1. Psoriasis (immune-mediated disease that affects the skin): 10 people, 18.18%
  2. Ankylosing Spondylitis (type of arthritis affecting the spine): 8 people, 14.55%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 14.55%
  4. Osteoporosis (bones weak and more likely to break): 4 people, 7.27%
  5. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 7.27%
  6. Uveitis (inflammation of the uvea): 3 people, 5.45%
  7. High Blood Cholesterol: 3 people, 5.45%
  8. Seasonal Allergy (allergic condition due to certain season): 2 people, 3.64%
  9. Depression: 2 people, 3.64%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 3.64%

* Approximation only. Some reports may have incomplete information.

Do you take Humira and have Stress urinary incontinence?

Check whether Stress urinary incontinence is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Stress urinary incontinence and when was it recovered:

Expand to all the drugs that have ingredients of adalimumab:

Alternative drugs to, pros and cons of Humira:

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Stress urinary incontinence treatments and more:

Common drugs associated with Stress urinary incontinence:

All the drugs that are associated with Stress urinary incontinence:

Common conditions associated with Stress urinary incontinence:

All the conditions that are associated with Stress urinary incontinence:

How the study uses the data?

The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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