Hydrochlorothiazide and Ototoxicity - a phase IV clinical study of FDA data

Summary:

Ototoxicity is found among people who take Hydrochlorothiazide, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Hydrochlorothiazide and have Ototoxicity. It is created by eHealthMe based on reports of 144,360 people who have side effects when taking Hydrochlorothiazide from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On Jul, 28, 2022

144,360 people reported to have side effects when taking Hydrochlorothiazide.
Among them, 6 people (0.0%) have Ototoxicity.


What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 148,540 Hydrochlorothiazide users for its effectiveness, alternative drugs and more.

What is Ototoxicity?

Ototoxicity (damage to the ear) is found to be associated with 595 drugs and 335 conditions by eHealthMe.

Number of Hydrochlorothiazide and Ototoxicity reports submitted per year:

Could Hydrochlorothiazide cause Ototoxicity?

Gender of people who have Ototoxicity when taking Hydrochlorothiazide *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Ototoxicity when taking Hydrochlorothiazide *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Hydrochlorothiazide *:

  1. Diclofenac: 2 people, 33.33%
  2. Ribavirin: 1 person, 16.67%
  3. Enalapril Maleate: 1 person, 16.67%
  4. Clopidogrel: 1 person, 16.67%

Common side effects people have besides Ototoxicity *:

  1. Dizziness: 4 people, 66.67%
  2. Weight Decreased: 3 people, 50.00%
  3. Muscle Aches (muscle pain): 3 people, 50.00%
  4. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 50.00%
  5. Fall: 3 people, 50.00%
  6. Gait Disturbance: 3 people, 50.00%
  7. Joint Pain: 3 people, 50.00%
  8. Herpes Zoster: 3 people, 50.00%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 50.00%
  10. Tinnitus (a ringing in the ears): 3 people, 50.00%

Common conditions people have *:

  1. Muscle Aches (muscle pain): 3 people, 50.00%
  2. Leishmaniasis (a disease caused by protozoan parasites that belong to the genus leishmania): 2 people, 33.33%
  3. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 1 person, 16.67%
  4. Herpes Zoster: 1 person, 16.67%
  5. Hepatitis C: 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrochlorothiazide and have Ototoxicity?

Check whether Ototoxicity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of Hydrochlorothiazide:

Ototoxicity treatments and more:

COVID vaccines that are related to Ototoxicity:

How severe was Ototoxicity and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide:

Common drugs associated with Ototoxicity:

All the drugs that are associated with Ototoxicity:

All the conditions that are associated with Ototoxicity:

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hydrochlorothiazide) and Hydrochlorothiazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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