Hydrocodone bitartrate and acetaminophen and Dupuytren's contracture - a phase IV clinical study of FDA data

• Hydrocodone bitartrate and acetaminophen (46,241 reports)

• Abdominal discomfort: 405 reports
• Abdominal distension: 202 reports
• Abdominal pain: 622 reports
• Abdominal pain upper: 558 reports
• Abnormal behavior: 181 reports
• Acute kidney failure: 1,008 reports
• Adverse drug reaction: 134 reports
• Aggression: 193 reports
• Agitation (state of anxiety or nervous excitement): 244 reports
• Alcoholism (problems with alcohol): 163 reports
• Anaemia (lack of blood): 479 reports
• Anger: 253 reports
• Anhedonia (inability to experience pleasure from activities usually found enjoyable): 321 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 559 reports
• Arrhythmias (irregular heartbeat): 216 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 256 reports
• Arthropathy: 141 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 101 reports
• Asthma: 136 reports
• Atelectasis (partial or complete collapse of the lung): 113 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 269 reports
• Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 106 reports
• Back injury: 124 reports
• Back pain: 951 reports
• Balance disorder: 351 reports
• Bipolar disorder (mood disorder): 186 reports
• Blood creatinine increased: 111 reports
• Blood glucose increased: 175 reports
• Bone density decreased: 105 reports
• Bone disorder: 178 reports
• Bone pain: 218 reports
• Breathing difficulty: 969 reports
• Breathing - slowed or stopped: 393 reports
• Broken bone: 109 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 270 reports
• Burning sensation: 129 reports
• Cardiac arrest: 473 reports
• Cardiac disorder: 1,301 reports
• Cardiac failure: 110 reports
• Cardiac failure congestive: 320 reports
• Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 511 reports
• Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 102 reports
• Cataract (clouding of the lens inside the eye): 138 reports
• Cellulitis (infection under the skin): 214 reports
• Chest pain: 611 reports
• Chills (felling of cold): 233 reports
• Cholecystitis (infection of gallbladder): 111 reports
• Cholecystitis chronic (long lasting infection of gallbladder): 309 reports
• Chronic kidney disease: 1,385 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 240 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 260 reports
• Completed suicide (act of taking one's own life): 1,708 reports
• Confusion: 108 reports
• Confusional state: 491 reports
• Consciousness - decreased: 173 reports
• Constipation: 1,050 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 155 reports
• Cough: 388 reports
• Crying: 106 reports
• Death: 3,224 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 445 reports
• Dehydration (dryness resulting from the removal of water): 358 reports
• Dental caries: 171 reports
• Dependence: 693 reports
• Depressed mood: 136 reports
• Depression: 2,595 reports
• Developmental delay: 1,788 reports
• Diabetes: 315 reports
• Diarrhea: 1,386 reports
• Disability: 2,204 reports
• Disease progression: 117 reports
• Disturbance in attention: 339 reports
• Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 113 reports
• Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 146 reports
• Dizziness: 1,173 reports
• Drowsiness: 692 reports
• Drug abuse and dependence: 1,943 reports
• Drug dependence: 7,145 reports
• Drug effect decreased: 144 reports
• Drug hypersensitivity: 218 reports
• Drug ineffective: 1,472 reports
• Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2,239 reports
• Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother): 1,691 reports
• Dry mouth: 246 reports
• Dry skin: 127 reports
• Dyspnea exertional: 122 reports
• Emotional disorder: 186 reports
• Emotional distress: 1,347 reports
• Enlarged heart: 143 reports
• Erection problems: 258 reports
• Fainting (loss of consciousness and postural tone): 201 reports
• Fall: 1,341 reports
• Fatigue (feeling of tiredness): 2,047 reports
• Fear: 139 reports
• Fever: 416 reports
• Fibromyalgia (a long-term condition which causes pain all over the body): 193 reports
• Flatulence (flatus expelled through the anus): 106 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 105 reports
• Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1,781 reports
• Gait disturbance: 580 reports
• Gallbladder disorder: 250 reports
• Gallstones (stone formation by bile component): 378 reports
• Gastric ulcer (stomach ulcer): 170 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 475 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 148 reports
• Generalized anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry): 114 reports
• General physical health deterioration (weak health status): 473 reports
• Haemoglobin decreased: 195 reports
• Haemorrhage (bleeding): 172 reports
• Haemorrhoids (a swollen vein or group of veins in the region of the anus): 167 reports
• Hair loss: 310 reports
• Hallucinations (sensations that appear real but are created by your mind): 293 reports
• Headache (pain in head): 1,433 reports
• Head injury: 677 reports
• Heart attack: 449 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 247 reports
• Heart rate increased: 175 reports
• Hepatitis c: 352 reports
• Herpes zoster: 133 reports
• Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 124 reports
• High blood cholesterol: 207 reports
• High blood pressure: 969 reports
• Hip fracture: 113 reports
• Hoarseness or changing voice: 108 reports
• Hospitalisation: 681 reports
• Hot flush (sudden feelings of heat): 167 reports
• Hyperhidrosis (abnormally increased sweating): 450 reports
• Hyperlipidaemia (presence of excess lipids in the blood): 119 reports
• Hypersensitivity: 165 reports
• Hypoaesthesia (reduced sense of touch or sensation): 505 reports
• Hypokalemia (low potassium): 126 reports
• Hypotension (abnormally low blood pressure): 426 reports
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 102 reports
• Ill-defined disorder: 106 reports
• Impaired driving ability: 160 reports
• Impaired healing: 104 reports
• Impaired work ability: 386 reports
• Indigestion: 291 reports
• Infection: 226 reports
• Influenza like illness: 130 reports
• Injection site pain: 124 reports
• Injury: 1,558 reports
• Insomnia (sleeplessness): 1,112 reports
• Interstitial nephritis (inflammation of the kidney): 180 reports
• Intervertebral disc degeneration (spinal disc degeneration): 216 reports
• Intervertebral disc protrusion (spinal disc protrusion): 244 reports
• Intestinal obstruction: 122 reports
• Irritability: 211 reports
• Irritable bowel syndrome: 137 reports
• Itching: 410 reports
• Joint pain: 861 reports
• Joint swelling: 200 reports
• Kidney stones: 267 reports
• Knee joint replacement: 109 reports
• Libido decreased (loss of interest in sex): 120 reports
• Limb injury: 149 reports
• Liver disorder (liver diseases): 118 reports
• Liver injury: 144 reports
• Loss of consciousness: 410 reports
• Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 205 reports
• Malaise (a feeling of general discomfort or uneasiness): 744 reports
• Malignant neoplasm progression (cancer tumour came back): 136 reports
• Maternal exposure during pregnancy (use of substance during pregnancy): 1,015 reports
• Memory loss: 1,176 reports
• Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 1,634 reports
• Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 340 reports
• Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 160 reports
• Migraine (headache): 318 reports
• Mobility decreased (ability to move is reduced): 188 reports
• Mood swings (an extreme or rapid change in mood): 294 reports
• Multiple myeloma (cancer of the plasma cells): 147 reports
• Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 120 reports
• Muscle aches (muscle pain): 275 reports
• Muscle spasms (muscle contraction): 603 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 174 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 147 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 109 reports
• Nasopharyngitis (inflammation of the nasopharynx): 235 reports
• Nausea (feeling of having an urge to vomit): 1,644 reports
• Nausea and vomiting: 1,144 reports
• Neck pain: 256 reports
• Nephrogenic anaemia (anaemia due to kidney disease): 172 reports
• Nerve injury: 138 reports
• Nervousness: 159 reports
• Nervous system disorder (a general class of medical conditions affecting the nervous system): 125 reports
• Neuropathy peripheral (surface nerve damage): 370 reports
• Nightmares (unpleasant dreams): 109 reports
• Nosebleed (bleeding from nose): 134 reports
• Oedema (fluid collection in tissue): 113 reports
• Oedema peripheral (superficial swelling): 363 reports
• Oral pain: 108 reports
• Oropharyngeal pain: 136 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 312 reports
• Osteomyelitis (infection of bone): 128 reports
• Osteonecrosis of jaw (death of bone of jaw): 158 reports
• Osteopenia (a condition where bone mineral density is lower than normal): 125 reports
• Osteoporosis (bones weak and more likely to break): 164 reports
• Overdose: 9,758 reports
• Pain: 5,660 reports
• Pain in extremity: 836 reports
• Pain in jaw: 126 reports
• Pancreatitis (inflammation of pancreas): 170 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 107 reports
• Panic disorder: 266 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 391 reports
• Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 137 reports
• Peripheral swelling: 301 reports
• Personality change: 164 reports
• Physical disability: 117 reports
• Pleural effusion (water on the lungs): 215 reports
• Pneumonia: 796 reports
• Post-traumatic stress disorder: 372 reports
• Pre-existing condition improved: 112 reports
• Psoriasis (immune-mediated disease that affects the skin): 107 reports
• Psychological trauma: 112 reports
• Psychotic disorder: 104 reports
• Pulmonary embolism (blockage of the main artery of the lung): 432 reports
• Pulmonary oedema (fluid accumulation in the lungs): 150 reports
• Quality of life decreased: 207 reports
• Rashes (redness): 761 reports
• Rectal haemorrhage (bleeding from anus): 127 reports
• Renal disorder (kidney disease): 179 reports
• Renal impairment (severely reduced kidney function): 144 reports
• Renal injury (kidney injury): 343 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 198 reports
• Restless leg syndrome (a powerful urge to move your legs): 111 reports
• Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 133 reports
• Rib fracture: 141 reports
• Road traffic accident: 725 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 437 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 261 reports
• Sinusitis (inflammation of sinus): 320 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 101 reports
• Skin discoloration: 116 reports
• Skin ulcer: 109 reports
• Sleep apnea syndrome: 248 reports
• Sleep disorder: 426 reports
• Social avoidant behavior: 113 reports
• Speech disorder: 127 reports
• Speech impairment (adult) (inability to speak (adult)): 204 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 159 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 133 reports
• Stomatitis (inflammation of mucous membrane of mouth): 147 reports
• Stress and anxiety: 3,384 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 461 reports
• Suicidal ideation: 639 reports
• Suicide attempt: 557 reports
• Surgery: 472 reports
• Swallowing difficulty: 274 reports
• Swelling: 242 reports
• Taste - impaired: 166 reports
• The flu (the flu is caused by an influenza virus): 205 reports
• Therapeutic response unexpected: 135 reports
• Thrombocytopenia (decrease of platelets in blood): 340 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 242 reports
• Tinnitus (a ringing in the ears): 126 reports
• Tooth abscess (pus formation in tooth): 102 reports
• Toothaches (tooth pain): 118 reports
• Tooth disorder (tooth disease): 177 reports
• Tooth extraction: 132 reports
• Tooth loss: 441 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 457 reports
• Type 2 diabetes: 184 reports
• Upper respiratory tract infection: 147 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 103 reports
• Urinary tract infection: 475 reports
• Urination - painful: 140 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 123 reports
• Vision blurred: 203 reports
• Visual impairment: 248 reports
• Vitamin supplementation: 245 reports
• Weakness: 1,269 reports
• Weight decreased: 775 reports
• Weight increased: 466 reports
• Weight loss: 169 reports
• White blood cell count decreased: 153 reports
• Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 706 reports

• Dupuytren's contracture (2,031 reports)

All the drugs that are associated with Dupuytren's contracture:

• Dupuytren's contracture (445 drugs)

All the conditions that are associated with Dupuytren's contracture:

• Dupuytren's contracture (208 conditions)

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