Hydrocodone and Dementia - a phase IV clinical study of FDA data
Summary:
Dementia is found among people who take Hydrocodone, especially for people who are female, 60+ old.
The phase IV clinical study analyzes which people take Hydrocodone and have Dementia. It is created by eHealthMe based on reports of 5,845 people who have side effects when taking Hydrocodone from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
5,845 people reported to have side effects when taking Hydrocodone.
Among them, 12 people (0.21%) have Dementia.
What is Hydrocodone?
Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 5,889 Hydrocodone users for its effectiveness, alternative drugs and more.
What is Dementia?
Dementia (madness) is found to be associated with 2,414 drugs and 1,724 conditions by eHealthMe.
Number of Hydrocodone and Dementia reports submitted per year:

Gender of people who have Dementia when taking Hydrocodone *:
- female: 63.64 %
- male: 36.36 %
Age of people who have Dementia when taking Hydrocodone *:
- 0-1: 10 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 90 %
Common drugs people take besides Hydrocodone *:
- Aspirin: 4 people, 33.33%
- Tylenol: 3 people, 25.00%
- Aleve: 3 people, 25.00%
- Metformin: 3 people, 25.00%
- Jakafi: 3 people, 25.00%
- Acetaminophen: 2 people, 16.67%
- Lyrica: 2 people, 16.67%
- Hydroxyzine: 2 people, 16.67%
- Escitalopram: 2 people, 16.67%
- Lexapro: 2 people, 16.67%
Common side effects people have besides Dementia *:
- Stress And Anxiety: 5 people, 41.67%
- Confusional State: 5 people, 41.67%
- Hypoaesthesia (reduced sense of touch or sensation): 3 people, 25.00%
- Fall: 3 people, 25.00%
- Drowsiness: 3 people, 25.00%
- Facial Paralysis (loss of function of face muscle): 3 people, 25.00%
- Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 3 people, 25.00%
- Muscle Rigidity (muscle stiffness): 3 people, 25.00%
- Agitation (state of anxiety or nervous excitement): 3 people, 25.00%
- Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 25.00%
Common conditions people have *:
- Pain: 2 people, 16.67%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 16.67%
- Quit Smoking: 1 person, 8.33%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 8.33%
- Neuralgia (pain in one or more nerves): 1 person, 8.33%
- Multiple Allergies (allergy to multiple agents): 1 person, 8.33%
- High Blood Cholesterol: 1 person, 8.33%
- Gastric Disorder (disease of stomach): 1 person, 8.33%
- Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%
- Bone Pain: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Hydrocodone and have Dementia?
Check whether Dementia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Dementia and when was it recovered:
Expand to all the drugs that have ingredients of hydrocodone bitartrate; ibuprofen:
Alternative drugs to, pros and cons of Hydrocodone:
- Hydrocodone (5,889 reports)
Common Hydrocodone side effects:
- Pain: 758 reports
- Stress and anxiety: 556 reports
- Fatigue (feeling of tiredness): 409 reports
- Chronic kidney disease: 301 reports
- Headache (pain in head): 288 reports
- Depression: 280 reports
Browse all side effects of Hydrocodone:
a b c d e f g h i j k l m n o p q r s t u v w x y zDementia treatments and more:
- Dementia (38,001 reports)
COVID vaccines that are related to Dementia:
- Dementia in Moderna COVID Vaccine
- Dementia in Pfizer BioNTech Covid Vaccine
- Dementia in Johnson and Johnson Covid Vaccine
Common drugs associated with Dementia:
- Aspirin: 1,497 reports
- Apixaban: 845 reports
- Aricept: 756 reports
- Seroquel: 743 reports
- Revlimid: 736 reports
- Omeprazole: 716 reports
- Furosemide: 698 reports
- Lyrica: 670 reports
- Nuplazid: 660 reports
- Lipitor: 648 reports
All the drugs that are associated with Dementia:
- Dementia (2,414 drugs)
Common conditions associated with Dementia:
- Parkinson's disease: 1,514 reports
- Rheumatoid arthritis: 1,059 reports
- High blood pressure: 1,014 reports
- Osteoporosis: 919 reports
- Multiple sclerosis: 917 reports
- Multiple myeloma: 911 reports
- Depression: 809 reports
All the conditions that are associated with Dementia:
- Dementia (1,724 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on hydrocodone bitartrate; ibuprofen (the active ingredients of Hydrocodone) and Hydrocodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Morphine vs. Prialt - 3 seconds ago
- Detrol and Diabetes - 5 seconds ago
- Phosphosoda and Renal Tubular Necrosis - 9 seconds ago
- Effexor and Bowel Movement Irregularity - 10 seconds ago
- Simethicone and Red Cell Distribution Width Increased - 10 seconds ago
- Vyvanse and Systemic Sclerosis (Scleroderma) - 14 seconds ago
- Flumadine and Pupil Fixed - 15 seconds ago
- Solu-Medrol and Nph Iletin I drug interaction - 16 seconds ago
- Oxybutynin and Rickets - 16 seconds ago
- Rashes in Excedrin, how severe and when it was recovered? - 18 seconds ago