Hydroxychloroquine sulfate and Dupuytren's contracture - a phase IV clinical study of FDA data


Dupuytren's contracture is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 40-49 old.

The phase IV clinical study analyzes which people take Hydroxychloroquine sulfate and have Dupuytren's contracture. It is created by eHealthMe based on reports of 40,773 people who have side effects when taking Hydroxychloroquine sulfate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 17, 2022

40,773 people reported to have side effects when taking Hydroxychloroquine sulfate.
Among them, 8 people (0.02%) have Dupuytren's contracture.

What is Hydroxychloroquine sulfate?

Hydroxychloroquine sulfate has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. eHealthMe is studying from 33,337 Hydroxychloroquine sulfate users for its effectiveness, alternative drugs and more.

What is Dupuytren's contracture?

Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 445 drugs and 208 conditions by eHealthMe.

Number of Hydroxychloroquine sulfate and Dupuytren's contracture reports submitted per year:

Could Hydroxychloroquine sulfate cause Dupuytren's contracture?

Gender of people who have Dupuytren's contracture when taking Hydroxychloroquine sulfate *:

  • female: 75 %
  • male: 25 %

Age of people who have Dupuytren's contracture when taking Hydroxychloroquine sulfate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 75 %
  • 50-59: 0.0 %
  • 60+: 25 %

Common drugs people take besides Hydroxychloroquine sulfate *:

  1. Hydroxyzine: 5 people, 62.50%
  2. Folic Acid: 4 people, 50.00%
  3. Vitamin B6: 3 people, 37.50%
  4. Rosuvastatin Calcium: 3 people, 37.50%
  5. Metformin: 3 people, 37.50%
  6. Calcium: 3 people, 37.50%
  7. Demerol: 3 people, 37.50%
  8. Synthroid: 3 people, 37.50%
  9. Tylenol: 3 people, 37.50%
  10. Azopt: 2 people, 25.00%

Common side effects people have besides Dupuytren's contracture *:

  1. Joint Pain: 7 people, 87.50%
  2. Cough: 5 people, 62.50%
  3. Swallowing Difficulty: 5 people, 62.50%
  4. High Blood Pressure: 5 people, 62.50%
  5. Nausea (feeling of having an urge to vomit): 5 people, 62.50%
  6. Diarrhea: 5 people, 62.50%
  7. Breathing Difficulty: 5 people, 62.50%
  8. Sleep Disorder: 5 people, 62.50%
  9. Joint Swelling: 5 people, 62.50%
  10. Asthma: 5 people, 62.50%

Common conditions people have *:

  1. Vasculitis (inflammation of a blood vessel or blood vessels): 3 people, 37.50%
  2. Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 3 people, 37.50%
  3. Myositis (inflammation of the muscles): 3 people, 37.50%
  4. Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 3 people, 37.50%
  5. Hypersensitivity: 2 people, 25.00%
  6. Headache (pain in head): 2 people, 25.00%
  7. Quit Smoking: 1 person, 12.50%
  8. Organising Pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue): 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxychloroquine sulfate and have Dupuytren's contracture?

Check whether Dupuytren's contracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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a b c d e f g h i j k l m n o p q r s t u v w x y z

Dupuytren's contracture treatments and more:

COVID vaccines that are related to Dupuytren's contracture:

Common drugs associated with Dupuytren's contracture:

All the drugs that are associated with Dupuytren's contracture:

Common conditions associated with Dupuytren's contracture:

  • Ra: 104 reports

All the conditions that are associated with Dupuytren's contracture:

How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate (the active ingredients of Hydroxychloroquine sulfate) and Hydroxychloroquine sulfate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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