Hydroxyzine and Drug level increased - a phase IV clinical study of FDA data

Summary:

Drug level increased is found among people who take Hydroxyzine, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Hydroxyzine and have Drug level increased. It is created by eHealthMe based on reports of 40,735 people who have side effects when taking Hydroxyzine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On Aug, 10, 2022

40,735 people reported to have side effects when taking Hydroxyzine.
Among them, 75 people (0.18%) have Drug level increased.


What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 36,931 Hydroxyzine users for its effectiveness, alternative drugs and more.

What is Drug level increased?

Drug level increased is found to be associated with 1,335 drugs and 1,059 conditions by eHealthMe.

Number of Hydroxyzine and Drug level increased reports submitted per year:

Could Hydroxyzine cause Drug level increased?

Time on Hydroxyzine when people have Drug level increased *:

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Drug level increased when taking Hydroxyzine *:

  • female: 48.57 %
  • male: 51.43 %

Age of people who have Drug level increased when taking Hydroxyzine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5.88 %
  • 20-29: 7.35 %
  • 30-39: 20.59 %
  • 40-49: 2.94 %
  • 50-59: 25.0 %
  • 60+: 38.24 %

Common drugs people take besides Hydroxyzine *:

  1. Fluoxetine: 19 people, 25.33%
  2. Omeprazole: 7 people, 9.33%
  3. Furosemide: 6 people, 8.00%
  4. Haloperidol: 6 people, 8.00%
  5. Cannabis: 6 people, 8.00%
  6. Depakote: 5 people, 6.67%
  7. Celecoxib: 5 people, 6.67%
  8. Risperidone: 5 people, 6.67%
  9. Budesonide: 5 people, 6.67%
  10. Prednisone: 5 people, 6.67%

Common side effects people have besides Drug level increased *:

  1. Overdose: 19 people, 25.33%
  2. Confusional State: 13 people, 17.33%
  3. Irritability: 13 people, 17.33%
  4. Tremor (trembling or shaking movements in one or more parts of your body): 12 people, 16.00%
  5. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 12 people, 16.00%
  6. Nephropathy Toxic (damage to kidney due to toxins): 12 people, 16.00%
  7. Nausea (feeling of having an urge to vomit): 11 people, 14.67%
  8. Dizziness: 11 people, 14.67%
  9. Drowsiness: 11 people, 14.67%
  10. Aggression: 10 people, 13.33%

Common conditions people have *:

  1. Suicidal Ideation: 11 people, 14.67%
  2. Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating): 6 people, 8.00%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 6.67%
  4. Eating Disorder: 5 people, 6.67%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 5.33%
  6. Hiv Infection: 4 people, 5.33%
  7. Sleep Disorder: 4 people, 5.33%
  8. High Blood Pressure: 4 people, 5.33%
  9. Bipolar Disorder (mood disorder): 4 people, 5.33%
  10. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and have Drug level increased?

Check whether Drug level increased is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of Hydroxyzine:

Drug level increased treatments and more:

COVID vaccines that are related to Drug level increased:

How severe was Drug level increased and when was it recovered:

Expand to all the drugs that have ingredients of hydroxyzine hydrochloride:

Common drugs associated with Drug level increased:

All the drugs that are associated with Drug level increased:

Common conditions associated with Drug level increased:

All the conditions that are associated with Drug level increased:

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine) and Hydroxyzine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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