Hydroxyzine and Yawning - a phase IV clinical study of FDA data


Yawning is found among people who take Hydroxyzine, especially for people who are female, 50-59 old.

The phase IV clinical study analyzes which people take Hydroxyzine and have Yawning. It is created by eHealthMe based on reports of 47,188 people who have side effects when taking Hydroxyzine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 16, 2023

47,188 people reported to have side effects when taking Hydroxyzine.
Among them, 9 people (0.02%) have Yawning.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 49,223 Hydroxyzine users for its effectiveness, alternative drugs and more.

What is Yawning?

Yawning (simultaneous inhalation of air and stretching of the eardrums, followed by exhalation of breath) is found to be associated with 1,099 drugs and 691 conditions by eHealthMe.

Number of Hydroxyzine and Yawning reports submitted per year:

Could Hydroxyzine cause Yawning?

Gender of people who have Yawning when taking Hydroxyzine *:

  • female: 85.71 %
  • male: 14.29 %

Age of people who have Yawning when taking Hydroxyzine *:

  • 0-1: 0.0 %
  • 2-9: 20 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 20 %
  • 40-49: 0.0 %
  • 50-59: 40 %
  • 60+: 20 %

Common drugs people take besides Hydroxyzine *:

  1. Xyrem: 2 people, 22.22%
  2. Morphine: 2 people, 22.22%
  3. Naloxone: 2 people, 22.22%
  4. Vitamin D: 1 person, 11.11%
  5. Veramyst: 1 person, 11.11%
  6. Apokyn: 1 person, 11.11%
  7. Bentyl: 1 person, 11.11%
  8. Concerta: 1 person, 11.11%
  9. Cymbalta: 1 person, 11.11%
  10. Effexor Xr: 1 person, 11.11%

Common side effects people have besides Yawning *:

  1. Nausea And Vomiting: 5 people, 55.56%
  2. Nausea (feeling of having an urge to vomit): 5 people, 55.56%
  3. Fatigue (feeling of tiredness): 4 people, 44.44%
  4. Rhinorrhea (watery mucus discharge from the nose): 4 people, 44.44%
  5. Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 3 people, 33.33%
  6. Diarrhea: 3 people, 33.33%
  7. Headache (pain in head): 3 people, 33.33%
  8. Lacrimation Increased: 3 people, 33.33%
  9. Malaise (a feeling of general discomfort or uneasiness): 3 people, 33.33%
  10. Hyperhidrosis (abnormally increased sweating): 3 people, 33.33%

Common conditions people have *:

  1. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 1 person, 11.11%
  2. Rhinorrhea (watery mucus discharge from the nose): 1 person, 11.11%
  3. Parkinson's Disease: 1 person, 11.11%
  4. Nausea (feeling of having an urge to vomit): 1 person, 11.11%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 11.11%
  6. Drug Dependence: 1 person, 11.11%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 11.11%
  8. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and have Yawning?

Check whether Yawning is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Yawning and when was it recovered:

Expand to all the drugs that have ingredients of hydroxyzine hydrochloride:

Alternative drugs to, pros and cons of Hydroxyzine:

Common Hydroxyzine side effects:

Browse all side effects of Hydroxyzine:

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Yawning treatments and more:

COVID vaccines that are related to Yawning:

Common drugs associated with Yawning:

All the drugs that are associated with Yawning:

Common conditions associated with Yawning:

All the conditions that are associated with Yawning:

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine) and Hydroxyzine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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