Hyzaar and Cardiac failure aggravated - a phase IV clinical study of FDA data
Summary:
We study 15,823 people who have side effects when taking Hyzaar. Cardiac failure aggravated is found, especially among people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Lasix and have Diabetes.
The phase IV clinical study analyzes which people take Hyzaar and have Cardiac failure aggravated. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
15,823 people reported to have side effects when taking Hyzaar.
Among them, 97 people (0.61%) have Cardiac failure aggravated.
What is Hyzaar?
Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is used in high blood pressure. Currently, eHealthMe is studying from 16,471 Hyzaar users.
What is Cardiac failure aggravated?
Cardiac failure aggravated is found to be associated with 1,850 drugs and 631 conditions by eHealthMe. Currently, we are studying 882 people who have Cardiac failure aggravated.
Number of Hyzaar and Cardiac failure aggravated reports submitted per year:

Time on Hyzaar when people have Cardiac failure aggravated *:
Gender of people who have Cardiac failure aggravated when taking Hyzaar*:
Age of people who have Cardiac failure aggravated when taking Hyzaar *:
Common drugs people take besides Hyzaar *:
Common side effects people have besides Cardiac failure aggravated *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Hyzaar and have Cardiac failure aggravated?
Check whether Cardiac failure aggravated is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Hyzaar side effects by duration, gender and age:
- Hyzaar side effects (16,471 reports)
Cardiac failure aggravated treatments and more:
- Cardiac failure aggravated (882 reports)
Common drugs associated with Cardiac failure aggravated:
- Furosemide: 8,202 reports
- Lasix: 5,410 reports
- Aspirin: 4,989 reports
- Entresto: 3,643 reports
- Spironolactone: 3,605 reports
- Prednisone: 3,290 reports
- Digoxin: 2,946 reports
- Ramipril: 2,935 reports
- Metformin: 2,905 reports
- Lopurin: 2,881 reports
All the drugs that are associated with Cardiac failure aggravated:
- Cardiac failure aggravated (1,850 drugs)
Common conditions associated with Cardiac failure aggravated:
- High blood pressure: 5,483 reports
- Primary pulmonary hypertension: 4,007 reports
- Atrial fibrillation/flutter: 3,555 reports
- Rheumatoid arthritis: 3,335 reports
- Diabetes: 3,178 reports
- Multiple myeloma: 2,367 reports
- Type 2 diabetes: 2,118 reports
- Pain: 1,782 reports
All the conditions that are associated with Cardiac failure aggravated:
- Cardiac failure aggravated (631 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on hydrochlorothiazide; losartan potassium (the active ingredients of Hyzaar) and Hyzaar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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