Ibuprofen and Depression - from FDA reports


Depression is found among people who take Ibuprofen, especially for people who are female, 40-49 old , have been taking the drug for < 1 month, also take medication Zometa, and have Birth control. This review analyzes which people have Depression with Ibuprofen. It is created by eHealthMe based on reports of 102,006 people who have side effects when taking Ibuprofen from FDA , and is updated regularly.



On Jun, 07, 2018

102,006 people reported to have side effects when taking Ibuprofen.
Among them, 3,582 people (3.51%) have Depression


Number of reports submitted per year:

Could Ibuprofen cause Depression?

Time on Ibuprofen when people have Depression *:

  • < 1 month: 35.08 %
  • 1 - 6 months: 9.42 %
  • 6 - 12 months: 5.24 %
  • 1 - 2 years: 4.71 %
  • 2 - 5 years: 17.8 %
  • 5 - 10 years: 14.14 %
  • 10+ years: 13.61 %

Gender of people who have Depression when taking Ibuprofen *:

  • female: 66.97 %
  • male: 33.03 %

Age of people who have Depression when taking Ibuprofen *:

  • 0-1: 0.07 %
  • 2-9: 0.28 %
  • 10-19: 5.5 %
  • 20-29: 16.68 %
  • 30-39: 16.44 %
  • 40-49: 23.13 %
  • 50-59: 20.31 %
  • 60+: 17.52 %

Top conditions involved for these people *:

  1. Birth Control: 355 people, 9.91%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 279 people, 7.79%
  3. Stress And Anxiety: 231 people, 6.45%
  4. High Blood Pressure: 222 people, 6.20%
  5. Acne (skin problems that cause pimples): 199 people, 5.56%
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Top co-used drugs for these people *:

  1. Zometa: 368 people, 10.27%
  2. Aspirin: 336 people, 9.38%
  3. Ambien: 334 people, 9.32%
  4. Zoloft: 332 people, 9.27%
  5. Vicodin: 319 people, 8.91%
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Top other side effects for these people *:

  1. Stress And Anxiety: 1,618 people, 45.17%
  2. Fatigue (feeling of tiredness): 760 people, 21.22%
  3. Nausea (feeling of having an urge to vomit): 653 people, 18.23%
  4. Injury: 638 people, 17.81%
  5. Insomnia (sleeplessness): 551 people, 15.38%
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* Approximation only. Some reports may have incomplete information.

What's next:

Do you take Ibuprofen and have Depression?



Related studies

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Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 107,282 users)

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What would happen?

Predict new side effects and undetected conditions when you take Ibuprofen and have Depression


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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