Ibuprofen and Earache - a phase IV clinical study of FDA data


Earache is found among people who take Ibuprofen, especially for people who are female, 40-49 old.

The phase IV clinical study analyzes which people take Ibuprofen and have Earache. It is created by eHealthMe based on reports of 184,299 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 18, 2022

184,299 people reported to have side effects when taking Ibuprofen.
Among them, 14 people (0.01%) have Earache.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 189,992 Ibuprofen users for its effectiveness, alternative drugs and more.

What is Earache?

Earache (ear pain) is found to be associated with 629 drugs by eHealthMe.

Number of Ibuprofen and Earache reports submitted per year:

Could Ibuprofen cause Earache?

Gender of people who have Earache when taking Ibuprofen *:

  • female: 78.57 %
  • male: 21.43 %

Age of people who have Earache when taking Ibuprofen *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 81.82 %
  • 50-59: 9.09 %
  • 60+: 9.09 %

Common drugs people take besides Ibuprofen *:

  1. Amoxicillin: 5 people, 35.71%
  2. Maxalt: 4 people, 28.57%
  3. Tylenol: 4 people, 28.57%
  4. Prandin: 3 people, 21.43%
  5. Glucophage: 3 people, 21.43%
  6. Rezulin: 3 people, 21.43%
  7. Ribavirin: 2 people, 14.29%
  8. Prevacid: 2 people, 14.29%
  9. Prilosec: 2 people, 14.29%
  10. Prinivil: 2 people, 14.29%

Common side effects people have besides Earache *:

  1. Tinnitus (a ringing in the ears): 7 people, 50.00%
  2. Deafness Neurosensory: 4 people, 28.57%
  3. Weight Decreased: 2 people, 14.29%
  4. Groin Swelling: 2 people, 14.29%
  5. Hypercalcaemia (elevated calcium (ca+) level in the blood): 2 people, 14.29%
  6. Hepatocellular Damage (liver damage): 2 people, 14.29%
  7. Hair Loss: 2 people, 14.29%
  8. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 2 people, 14.29%
  9. Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 2 people, 14.29%
  10. Gallstones (stone formation by bile component): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Earache?

Check whether Earache is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of Ibuprofen:

Earache treatments and more:

COVID vaccines that are related to Earache:

How severe was Earache and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

All the drugs that are associated with Earache:

All the conditions that are associated with Earache:

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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