Ibuprofen and Irritable bowel syndrome - a phase IV clinical study of FDA data
Summary:
Irritable bowel syndrome is found among people who take Ibuprofen, especially for people who are female, 40-49 old, have been taking the drug for 10+ years.
The phase IV clinical study analyzes which people take Ibuprofen and have Irritable bowel syndrome. It is created by eHealthMe based on reports of 204,574 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
204,574 people reported to have side effects when taking Ibuprofen.
Among them, 2,355 people (1.15%) have Irritable bowel syndrome.
What is Ibuprofen?
Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 210,453 Ibuprofen users for its effectiveness, alternative drugs and more.
What is Irritable bowel syndrome?
Irritable bowel syndrome is found to be associated with 2,637 drugs and 2,037 conditions by eHealthMe.
Number of Ibuprofen and Irritable bowel syndrome reports submitted per year:

Time on Ibuprofen when people have Irritable bowel syndrome *:
Gender of people who have Irritable bowel syndrome when taking Ibuprofen*:
Age of people who have Irritable bowel syndrome when taking Ibuprofen *:
Common drugs people take besides Ibuprofen *:
Common side effects people have besides Irritable bowel syndrome *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Ibuprofen and have Irritable bowel syndrome?
Check whether Irritable bowel syndrome is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Related studies
How severe was Irritable bowel syndrome and when was it recovered:
Expand to all the drugs that have ingredients of ibuprofen:
- Irritable bowel syndrome and drugs with ingredients of ibuprofen (2,722 reports)
Alternative drugs to, pros and cons of Ibuprofen:
- Ibuprofen (210,453 reports)
Common Ibuprofen side effects:
- Pain: 17,474 reports
- Fatigue (feeling of tiredness): 15,323 reports
- Drug ineffective: 14,992 reports
- Headache (pain in head): 13,160 reports
- Rashes (redness): 11,328 reports
- Breathing difficulty: 10,784 reports
- Joint pain: 10,717 reports
- Nausea and vomiting: 10,601 reports
Browse all side effects of Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zIrritable bowel syndrome treatments and more:
- Irritable bowel syndrome (43,357 reports)
COVID vaccines that are related to Irritable bowel syndrome:
- Irritable bowel syndrome in Moderna COVID Vaccine
- Irritable bowel syndrome in Pfizer BioNTech Covid Vaccine
- Irritable bowel syndrome in Johnson and Johnson Covid Vaccine
Common drugs associated with Irritable bowel syndrome:
- Accutane: 4,848 reports
- Prednisone: 2,927 reports
- Methotrexate: 2,728 reports
- Enbrel: 2,492 reports
- Profen: 2,356 reports
- Ibu: 2,355 reports
- Ibuprofen: 2,355 reports
- Humira: 2,258 reports
- Cimzia: 2,159 reports
- Simponi: 2,131 reports
All the drugs that are associated with Irritable bowel syndrome:
- Irritable bowel syndrome (2,637 drugs)
Common conditions associated with Irritable bowel syndrome:
- Acne: 3,224 reports
- Rheumatoid arthritis: 3,051 reports
- High blood pressure: 1,869 reports
- Osteoporosis: 1,043 reports
- Pain: 876 reports
- Multiple sclerosis: 850 reports
- Depression: 778 reports
All the conditions that are associated with Irritable bowel syndrome:
- Irritable bowel syndrome (2,037 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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