Will you have Rhabdomyolysis with Ibuprofen - from FDA reports

Summary

Rhabdomyolysis is found among people who take Ibuprofen, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Lipitor, and have High blood cholesterol. This study is created by eHealthMe based on reports of 125,105 people who have side effects when taking Ibuprofen from FDA, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Synonyms of Rhabdomyolysis are also considered in the study.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 130,381 users)

What is Rhabdomyolysis?

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down) has been reported by people with high blood cholesterol, hyperlipidaemia, high blood pressure (latest reports from 46,041 Rhabdomyolysis patients).

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Mar, 16, 2019

125,105 people reported to have side effects when taking Ibuprofen.
Among them, 558 people (0.45%) have Rhabdomyolysis


Number of reports submitted per year:

Could Ibuprofen cause Rhabdomyolysis?

Time on Ibuprofen when people have Rhabdomyolysis *:

  • < 1 month: 79.22 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 1.3 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 3.9 %
  • 5 - 10 years: 1.3 %
  • 10+ years: 0.0 %

Gender of people who have Rhabdomyolysis when taking Ibuprofen *:

  • female: 47.07 %
  • male: 52.93 %

Age of people who have Rhabdomyolysis when taking Ibuprofen *:

  • 0-1: 1.02 %
  • 2-9: 2.45 %
  • 10-19: 4.7 %
  • 20-29: 8.79 %
  • 30-39: 12.27 %
  • 40-49: 14.93 %
  • 50-59: 13.5 %
  • 60+: 42.33 %

Top conditions involved for these people *:

  1. High Blood Cholesterol: 65 people, 11.65%
  2. High Blood Pressure: 53 people, 9.50%
  3. Depression: 34 people, 6.09%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 31 people, 5.56%
  5. Joint Pain: 30 people, 5.38%
  6. Urinary Tract Infection: 17 people, 3.05%
  7. Fever: 17 people, 3.05%
  8. Sleep Disorder: 17 people, 3.05%
  9. Agitation (state of anxiety or nervous excitement): 16 people, 2.87%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 16 people, 2.87%

Top co-used drugs for these people *:

  1. Acetaminophen: 37 people, 6.63%
  2. Lipitor: 37 people, 6.63%
  3. Lisinopril: 36 people, 6.45%
  4. Lopid: 33 people, 5.91%
  5. Furosemide: 32 people, 5.73%
  6. Simvastatin: 28 people, 5.02%
  7. Omeprazole: 26 people, 4.66%
  8. Hydrochlorothiazide: 25 people, 4.48%
  9. Baycol: 25 people, 4.48%
  10. Crestor: 24 people, 4.30%

Top other side effects for these people *:

  1. Renal Failure Acute (rapid kidney dysfunction): 121 people, 21.68%
  2. Blood Creatine Phosphokinase Increased: 58 people, 10.39%
  3. Intentional Overdose: 45 people, 8.06%
  4. Weakness: 41 people, 7.35%
  5. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 39 people, 6.99%
  6. Hypotension (abnormally low blood pressure): 38 people, 6.81%
  7. Acute Kidney Failure: 38 people, 6.81%
  8. Muscle Aches (muscle pain): 37 people, 6.63%
  9. Fatigue (feeling of tiredness): 37 people, 6.63%
  10. Cardiac Arrest: 35 people, 6.27%

* Approximation only. Some reports may have incomplete information.

Do you have Rhabdomyolysis while taking Ibuprofen?


You are not alone:




Related publications that referenced our studies


Results from eHealthMe (non-FDA) reports of Rhabdomyolysis with Ibuprofen

Severity of Rhabdomyolysis *:
  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 0.0 %
  • most severe: 100 %
Effectiveness of Ibuprofen when people have Rhabdomyolysis *:
  • not at all: 0.0 %
  • somewhat: 0.0 %
  • moderate: 0.0 %
  • high: 0.0 %
  • very high: 100 %
Race of the people *:
  • African American, Non-Hispanic: 0.0 %
  • American Indian/Alaska Native: 0.0 %
  • Asian: 0.0 %
  • Hispanic: 0.0 %
  • Native Hawaiians/Pacific Islanders: 0.0 %
  • Two or more races: 0.0 %
  • White, Non-Hispanic: 100 %

* Approximation only.


Related studies

Drugs that are associated with Rhabdomyolysis
Rhabdomyolysis (2,033 drugs)
Could your condition cause Rhabdomyolysis
Rhabdomyolysis (1,716 conditions)
Ibuprofen side effects

Browse side effects by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Browse all side effects of Ibuprofen
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Ibuprofen and have Rhabdomyolysis



FDA reports used in this study


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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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