Imuran and Pathological fracture - a phase IV clinical study of FDA data
Summary:
Pathological fracture is found among people who take Imuran, especially for people who are female, 40-49 old.
The phase IV clinical study analyzes which people take Imuran and have Pathological fracture. It is created by eHealthMe based on reports of 26,904 people who have side effects when taking Imuran from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
26,904 people reported to have side effects when taking Imuran.
Among them, 24 people (0.09%) have Pathological fracture.
What is Imuran?
Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 27,576 Imuran users for its effectiveness, alternative drugs and more.
What is Pathological fracture?
Pathological fracture (broken bone caused by disease) is found to be associated with 1,093 drugs and 456 conditions by eHealthMe.
Number of Imuran and Pathological fracture reports submitted per year:
Gender of people who have Pathological fracture when taking Imuran *:
- female: 91.67 %
- male: 8.33 %
Age of people who have Pathological fracture when taking Imuran *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 5.56 %
- 20-29: 5.56 %
- 30-39: 0.0 %
- 40-49: 72.22 %
- 50-59: 5.56 %
- 60+: 11.11 %
Common drugs people take besides Imuran *:
- Zometa: 18 people, 75.00%
- Aredia: 18 people, 75.00%
- Lortab: 16 people, 66.67%
- Diflucan: 16 people, 66.67%
- Amoxicillin: 16 people, 66.67%
- Nexium: 15 people, 62.50%
- Bactrim Ds: 15 people, 62.50%
- Clonidine: 15 people, 62.50%
- Restoril: 14 people, 58.33%
- Dexamethasone: 14 people, 58.33%
Common side effects people have besides Pathological fracture *:
- Osteonecrosis Of Jaw (death of bone of jaw): 18 people, 75.00%
- Atelectasis (partial or complete collapse of the lung): 18 people, 75.00%
- Hypokalemia (low potassium): 18 people, 75.00%
- Mucosal Inflammation (infection of mucous membrane): 18 people, 75.00%
- Pain: 18 people, 75.00%
- Pleural Effusion (water on the lungs): 18 people, 75.00%
- Hyperkalemia (damage to or disease of the kidney): 17 people, 70.83%
- Inflammation: 17 people, 70.83%
- Chest Pain: 17 people, 70.83%
- Pneumonia: 17 people, 70.83%
Common conditions people have *:
- High Blood Pressure: 15 people, 62.50%
- Multiple Myeloma (cancer of the plasma cells): 14 people, 58.33%
- Anaemia (lack of blood): 7 people, 29.17%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 29.17%
- Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 7 people, 29.17%
- Osteoporosis (bones weak and more likely to break): 4 people, 16.67%
- Metastases To Bone (cancer spreads to bone): 2 people, 8.33%
- Breast Cancer: 1 person, 4.17%
- Diabetes: 1 person, 4.17%
- Gastric Disorder (disease of stomach): 1 person, 4.17%
* Approximation only. Some reports may have incomplete information.
Do you take Imuran and have Pathological fracture?
Check whether Pathological fracture is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Almarshad HA, "Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine", African Journal of Pharmacy and Pharmacology, 2014 Nov .
Related studies
Alternative drugs to, pros and cons of Imuran:
- Imuran (27,576 reports)
Pathological fracture treatments and more:
- Pathological fracture (6,591 reports)
COVID vaccines that are related to Pathological fracture:
- Pathological fracture in Moderna COVID Vaccine
- Pathological fracture in Pfizer BioNTech Covid Vaccine
- Pathological fracture in Johnson and Johnson Covid Vaccine
How severe was Pathological fracture and when was it recovered:
Expand to all the drugs that have ingredients of azathioprine:
Common drugs associated with Pathological fracture:
- Acetaminophen: 142 reports
- Actonel: 392 reports
- Actos: 101 reports
- Adriamycin pfs: 116 reports
- Albuterol: 114 reports
- Alendronate sodium: 304 reports
- Allegra: 111 reports
- Allopurinol: 116 reports
- Ambien: 276 reports
- Amoxicillin: 227 reports
- Aranesp: 163 reports
- Aredia: 812 reports
- Arimidex: 148 reports
- Aromasin: 133 reports
- Aspirin: 502 reports
- Atenolol: 169 reports
- Ativan: 201 reports
- Augmentin: 109 reports
- Bactrim: 125 reports
- Benadryl: 135 reports
- Boniva: 199 reports
- Calcium: 228 reports
- Carboplatin: 119 reports
- Celebrex: 320 reports
- Celexa: 123 reports
- Cephalexin: 113 reports
- Clopra: 125 reports
- Colace: 204 reports
- Coumadin: 351 reports
- Crestor: 109 reports
- Cyclophosphamide: 148 reports
- Cymbalta: 158 reports
- Cytoxan: 142 reports
- Decadron: 280 reports
- Dexamethasone: 416 reports
- Dilaudid: 177 reports
- Duragesic-100: 120 reports
- Effexor: 153 reports
- Enbrel: 192 reports
- Faslodex: 174 reports
- Femara: 246 reports
- Fentanyl: 191 reports
- Fluconazole: 109 reports
- Fluorouracil: 103 reports
- Folic acid: 185 reports
- Forteo: 194 reports
- Fosamax: 916 reports
- Furosemide: 161 reports
- Gabapentin: 166 reports
- Gemzar: 108 reports
- Heparin: 137 reports
- Herceptin: 138 reports
- Humira: 174 reports
- Hydrochlorothiazide: 185 reports
- Ibuprofen: 170 reports
- Keflex: 129 reports
- Lasix: 313 reports
- Levaquin: 209 reports
- Levothyroxine sodium: 135 reports
- Lexapro: 158 reports
- Lipitor: 300 reports
- Lisinopril: 264 reports
- Lorazepam: 200 reports
- Lortab: 116 reports
- Lovenox: 135 reports
- Lyrica: 136 reports
- Megace: 127 reports
- Metformin: 133 reports
- Methotrexate: 299 reports
- Metoclopramide: 124 reports
- Metronidazole: 113 reports
- Morphine: 359 reports
- Morphine sulfate: 113 reports
- Navelbine: 118 reports
- Neurontin: 256 reports
- Nexium: 281 reports
- Norvasc: 121 reports
- Omeprazole: 295 reports
- Ondansetron: 106 reports
- Oxycodone: 288 reports
- Oxycontin: 399 reports
- Pantoprazole: 143 reports
- Paxil: 125 reports
- Pepcid: 117 reports
- Percocet: 239 reports
- Peridex: 173 reports
- Plavix: 118 reports
- Prednisolone: 145 reports
- Prednisone: 617 reports
- Prevacid: 190 reports
- Prilosec: 262 reports
- Prolia: 365 reports
- Protonix: 303 reports
- Reglan: 151 reports
- Revlimid: 414 reports
- Senna: 102 reports
- Simvastatin: 173 reports
- Synthroid: 242 reports
- Tamoxifen citrate: 101 reports
- Taxol: 147 reports
- Taxotere: 234 reports
- Tramadol: 143 reports
- Tylenol: 207 reports
- Velcade: 240 reports
- Vicodin: 219 reports
- Vioxx: 152 reports
- Vitamin d: 154 reports
- Vitamins: 213 reports
- Warfarin sodium: 156 reports
- Xanax: 147 reports
- Xeloda: 230 reports
- Zantac: 117 reports
- Zocor: 170 reports
- Zofran: 263 reports
- Zoledronic acid: 110 reports
- Zoloft: 119 reports
- Zometa: 1,232 reports
- Zyrtec: 107 reports
All the drugs that are associated with Pathological fracture:
- Pathological fracture (1,093 drugs)
Common conditions associated with Pathological fracture:
- Alternative medicine - pain relief: 237 reports
- Breast cancer: 290 reports
- Breast cancer metastatic: 198 reports
- Cancer - breast: 289 reports
- Hbp: 177 reports
- High blood pressure: 177 reports
- Htn: 177 reports
- Hypertension: 181 reports
- Malignant plasmacytoma: 807 reports
- Metastases to bone: 423 reports
- Multiple myeloma: 807 reports
- Osteopenia: 214 reports
- Osteoporosis: 1,174 reports
- Osteoporosis postmenopausal: 176 reports
- Osteoporosis post-menopausal: 185 reports
- Pain: 263 reports
- Plasma cell dyscrasia: 807 reports
- Plasma cell myeloma: 807 reports
- Plasmacytoma of bone: 807 reports
- Preventive health care: 117 reports
- Rheumatoid arthritis: 244 reports
All the conditions that are associated with Pathological fracture:
- Pathological fracture (456 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on azathioprine (the active ingredients of Imuran) and Imuran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Stable Angina and Weight Increased - 6 seconds ago
- Trazodone Hydrochloride and Rhinitis - 6 seconds ago
- Orencia and Eye Haemorrhage - 11 seconds ago
- Wellbutrin and B12 drug interaction - 31 seconds ago
- Nasonex and Heart Transplant - 55 seconds ago