Insulin and Implant site reaction - a phase IV clinical study of FDA data


Implant site reaction is reported only by a few people who take Insulin.

The phase IV clinical study analyzes which people take Insulin and have Implant site reaction. It is created by eHealthMe based on reports of 49,604 people who have side effects while taking Insulin from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

49,604 people reported to have side effects when taking Insulin.
Among them, 5 people (0.01%) have Implant site reaction.

What is Insulin?

Insulin has active ingredients of insulin pork. It is often used in diabetes. eHealthMe is studying from 50,149 Insulin users for its effectiveness, alternative drugs and more.

What is Implant site reaction?

Implant site reaction is found to be associated with 437 drugs and 173 conditions by eHealthMe.

Number of Insulin and Implant site reaction reports submitted per year:

Could Insulin cause Implant site reaction?

Gender of people who have Implant site reaction when taking Insulin *:

  • female: 75 %
  • male: 25 %

Age of people who have Implant site reaction when taking Insulin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 33.33 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 66.67 %

Common drugs people take besides Insulin *:

  1. Vasotec: 1 person, 20.00%
  2. Lopressor: 1 person, 20.00%
  3. Actos: 1 person, 20.00%
  4. Aggrastat: 1 person, 20.00%
  5. Albuterol: 1 person, 20.00%
  6. Bisoprolol Fumarate: 1 person, 20.00%
  7. Eptifibatide: 1 person, 20.00%
  8. Furosemide: 1 person, 20.00%
  9. Glyburide: 1 person, 20.00%
  10. Heparin: 1 person, 20.00%

Common side effects people have besides Implant site reaction *:

  1. Thrombocytopenia (decrease of platelets in blood): 2 people, 40.00%
  2. Heart Attack: 2 people, 40.00%
  3. Blood Urea Increased: 2 people, 40.00%
  4. Hypotension (abnormally low blood pressure): 2 people, 40.00%
  5. Traumatic Lung Injury: 1 person, 20.00%
  6. Device Expulsion: 1 person, 20.00%
  7. Feeling Hot: 1 person, 20.00%
  8. Fall: 1 person, 20.00%
  9. Enlarged Prostate: 1 person, 20.00%
  10. Endocarditis (inflammation in heart muscle): 1 person, 20.00%

Common conditions people have *:

  1. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Insulin and have Implant site reaction?

Check whether Implant site reaction is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Implant site reaction and when was it recovered:

Expand to all the drugs that have ingredients of insulin pork:

Alternative drugs to, pros and cons of Insulin:

Common Insulin side effects:

Browse all side effects of Insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Implant site reaction treatments and more:

COVID vaccines that are related to Implant site reaction:

Common drugs associated with Implant site reaction:

All the drugs that are associated with Implant site reaction:

Common conditions associated with Implant site reaction:

All the conditions that are associated with Implant site reaction:

How the study uses the data?

The study uses data from the FDA. It is based on insulin pork (the active ingredients of Insulin) and Insulin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: