Invokana and Urine output decreased - a phase IV clinical study of FDA data


Urine output decreased is found among people who take Invokana, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Invokana and have Urine output decreased. It is created by eHealthMe based on reports of 28,607 people who have side effects when taking Invokana from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 08, 2022

28,607 people reported to have side effects when taking Invokana.
Among them, 18 people (0.06%) have Urine output decreased.

What is Invokana?

Invokana has active ingredients of canagliflozin. It is often used in diabetes. eHealthMe is studying from 28,852 Invokana users for its effectiveness, alternative drugs and more.

What is Urine output decreased?

Urine output decreased is found to be associated with 1,792 drugs and 1,138 conditions by eHealthMe.

Number of Invokana and Urine output decreased reports submitted per year:

Could Invokana cause Urine output decreased?

Time on Invokana when people have Urine output decreased *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Urine output decreased when taking Invokana *:

  • female: 33.33 %
  • male: 66.67 %

Age of people who have Urine output decreased when taking Invokana *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 7.69 %
  • 40-49: 0.0 %
  • 50-59: 7.69 %
  • 60+: 84.62 %

Common drugs people take besides Invokana *:

  1. Pantoprazole: 8 people, 44.44%
  2. Janumet: 8 people, 44.44%
  3. Fish Oil: 8 people, 44.44%
  4. Coenzyme Q10: 7 people, 38.89%
  5. Lantus: 7 people, 38.89%
  6. Clopidogrel: 5 people, 27.78%
  7. Pradaxa: 4 people, 22.22%
  8. Metformin: 2 people, 11.11%
  9. Xarelto: 2 people, 11.11%
  10. Coq10: 2 people, 11.11%

Common side effects people have besides Urine output decreased *:

  1. Hyperhidrosis (abnormally increased sweating): 8 people, 44.44%
  2. Back Pain: 8 people, 44.44%
  3. Breathing Difficulty: 7 people, 38.89%
  4. Walking Disability: 7 people, 38.89%
  5. Infrequent Bowel Movements: 7 people, 38.89%
  6. Spinal Cord Infarction (tissue damage of spinal cord due to lack of blood supply): 7 people, 38.89%
  7. Loss Of Control Of Legs: 7 people, 38.89%
  8. Pain: 7 people, 38.89%
  9. Nausea And Vomiting: 7 people, 38.89%
  10. Nausea (feeling of having an urge to vomit): 7 people, 38.89%

Common conditions people have *:

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 44.44%
  2. Heart Attack: 7 people, 38.89%
  3. High Blood Cholesterol: 2 people, 11.11%
  4. Thyroid Diseases: 2 people, 11.11%
  5. Blood Glucose Abnormal: 1 person, 5.56%
  6. Breathing Difficulty: 1 person, 5.56%
  7. Cardiac Failure Congestive: 1 person, 5.56%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.56%
  9. Drowsiness: 1 person, 5.56%
  10. Erection Problems: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Invokana and have Urine output decreased?

Check whether Urine output decreased is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Urine output decreased and when was it recovered:

Expand to all the drugs that have ingredients of canagliflozin:

Alternative drugs to, pros and cons of Invokana:

Common Invokana side effects:

Browse all side effects of Invokana:

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Urine output decreased treatments and more:

COVID vaccines that are related to Urine output decreased:

Common drugs associated with Urine output decreased:

All the drugs that are associated with Urine output decreased:

Common conditions associated with Urine output decreased:

All the conditions that are associated with Urine output decreased:

How the study uses the data?

The study uses data from the FDA. It is based on canagliflozin (the active ingredients of Invokana) and Invokana (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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