Who have Low blood pressure with Irinotecan hydrochloride - from FDA reports


Low blood pressure is found among people who take Irinotecan hydrochloride, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Fluorouracil, and have Colon cancer. This study is created by eHealthMe based on reports of 3,308 people who have side effects when taking Irinotecan hydrochloride from FDA, and is updated regularly.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.


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On Feb, 21, 2019

3,308 people reported to have side effects when taking Irinotecan hydrochloride.
Among them, 52 people (1.57%) have Low blood pressure


Number of reports submitted per year:

Could Irinotecan hydrochloride cause Low blood pressure?

Time on Irinotecan hydrochloride when people have Low blood pressure *:

  • < 1 month: 80 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Low blood pressure when taking Irinotecan hydrochloride *:

  • female: 38 %
  • male: 62 %

Age of people who have Low blood pressure when taking Irinotecan hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.17 %
  • 20-29: 4.17 %
  • 30-39: 0.0 %
  • 40-49: 8.33 %
  • 50-59: 14.58 %
  • 60+: 68.75 %

Top conditions involved for these people *:

  1. Colon Cancer: 13 people, 25.00%
  2. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 7 people, 13.46%
  3. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 4 people, 7.69%
  4. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 4 people, 7.69%
  5. High Blood Pressure: 3 people, 5.77%
  6. Large Intestine Carcinoma (cancer of large intestine): 3 people, 5.77%
  7. Rectal Cancer (cancer of rectum): 3 people, 5.77%
  8. Gastrointestinal Carcinoma (cancer of stomach or intestine): 2 people, 3.85%
  9. Metastases To Peritoneum (cancer spreads to peritoneum): 2 people, 3.85%
  10. Neoplasm Malignant (cancer tumour): 2 people, 3.85%

Top co-used drugs for these people *:

  1. Fluorouracil: 18 people, 34.62%
  2. Avastin: 14 people, 26.92%
  3. Decadron: 10 people, 19.23%
  4. Temodar: 8 people, 15.38%
  5. Coumadin: 7 people, 13.46%
  6. Lipitor: 6 people, 11.54%
  7. Lasix: 6 people, 11.54%
  8. Lotrel: 6 people, 11.54%
  9. Toprol-Xl: 6 people, 11.54%
  10. Leucovorin Calcium: 4 people, 7.69%

Top other side effects for these people *:

  1. Diarrhea: 12 people, 23.08%
  2. Weakness: 8 people, 15.38%
  3. Renal Failure Acute (rapid kidney dysfunction): 8 people, 15.38%
  4. Arrhythmias (irregular heartbeat): 8 people, 15.38%
  5. Nausea (feeling of having an urge to vomit): 8 people, 15.38%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 13.46%
  7. Fatigue (feeling of tiredness): 7 people, 13.46%
  8. Nausea And Vomiting: 7 people, 13.46%
  9. Breathing Difficulty: 6 people, 11.54%
  10. Abdominal Pain: 6 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you have Low blood pressure while taking Irinotecan hydrochloride?


You are not alone:




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Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Browse all side effects of Irinotecan hydrochloride
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What would happen?

Predict new side effects and undetected conditions when you take Irinotecan hydrochloride and have Low blood pressure


FDA reports used in this study



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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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