Irinotecan hydrochloride and Low blood pressure - from FDA reports


Low blood pressure is found among people who take Irinotecan hydrochloride, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Fluorouracil, and have Colon cancer. This study is created by eHealthMe based on reports of 2,750 people who have side effects when taking Irinotecan hydrochloride from FDA, and is updated regularly.

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On Aug, 10, 2018

2,750 people reported to have side effects when taking Irinotecan hydrochloride.
Among them, 47 people (1.71%) have Low blood pressure


Number of reports submitted per year:

Could Irinotecan hydrochloride cause Low blood pressure?

Time on Irinotecan hydrochloride when people have Low blood pressure *:

  • < 1 month: 78.57 %
  • 1 - 6 months: 21.43 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Low blood pressure when taking Irinotecan hydrochloride *:

  • female: 37.78 %
  • male: 62.22 %

Age of people who have Low blood pressure when taking Irinotecan hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.55 %
  • 20-29: 4.55 %
  • 30-39: 0.0 %
  • 40-49: 6.82 %
  • 50-59: 15.91 %
  • 60+: 68.18 %

Top conditions involved for these people *:

  1. Colon Cancer: 12 people, 25.53%
  2. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 7 people, 14.89%
  3. Rectal Cancer (cancer of rectum): 3 people, 6.38%
  4. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 3 people, 6.38%
  5. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 3 people, 6.38%
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Top co-used drugs for these people *:

  1. Fluorouracil: 18 people, 38.30%
  2. Avastin: 11 people, 23.40%
  3. Decadron: 10 people, 21.28%
  4. Temodar: 8 people, 17.02%
  5. Coumadin: 7 people, 14.89%
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Top other side effects for these people *:

  1. Diarrhea: 11 people, 23.40%
  2. Renal Failure Acute (rapid kidney dysfunction): 8 people, 17.02%
  3. Nausea And Vomiting: 7 people, 14.89%
  4. Arrhythmias (irregular heartbeat): 7 people, 14.89%
  5. Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 14.89%
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* Approximation only. Some reports may have incomplete information.

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