Isoniazid and Weakness - from FDA reports

Weakness is found among people who take Isoniazid, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Pyrazinamide, and have Rheumatoid arthritis. This study is created by eHealthMe based on reports of 12,349 people who have side effects when taking Isoniazid from FDA, and is updated regularly.

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On Oct, 20, 2018

12,349 people reported to have side effects when taking Isoniazid.
Among them, 364 people (2.95%) have Weakness

Number of reports submitted per year:

Could Isoniazid cause Weakness?

Time on Isoniazid when people have Weakness *:

  • < 1 month: 31.48 %
  • 1 - 6 months: 53.7 %
  • 6 - 12 months: 14.81 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Weakness when taking Isoniazid *:

  • female: 54.08 %
  • male: 45.92 %

Age of people who have Weakness when taking Isoniazid *:

  • 0-1: 0.0 %
  • 2-9: 0.31 %
  • 10-19: 4.66 %
  • 20-29: 11.18 %
  • 30-39: 16.77 %
  • 40-49: 13.66 %
  • 50-59: 17.08 %
  • 60+: 36.34 %

Top conditions involved for these people *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 70 people, 19.23%
  2. Hiv Infection: 46 people, 12.64%
  3. High Blood Pressure: 19 people, 5.22%
  4. Preventive Health Care: 16 people, 4.40%
  5. Latent Tuberculosis (hidden tuberculosis): 12 people, 3.30%

Click here to view more results or personalize the results to your gender and age

Top co-used drugs for these people *:

  1. Pyrazinamide: 69 people, 18.96%
  2. Humira: 56 people, 15.38%
  3. Methotrexate: 33 people, 9.07%
  4. Pyridoxine: 28 people, 7.69%
  5. Ethambutol Hydrochloride: 26 people, 7.14%

Click here to view more results or personalize the results to your gender and age

Top other side effects for these people *:

  1. Fever: 84 people, 23.08%
  2. Nausea (feeling of having an urge to vomit): 72 people, 19.78%
  3. Nausea And Vomiting: 65 people, 17.86%
  4. Fatigue (feeling of tiredness): 61 people, 16.76%
  5. Dizziness: 52 people, 14.29%

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

Do you have Weakness while taking Isoniazid?

You are not alone:

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Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from Isoniazid 12,654 users)


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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