Isosorbide dinitrate and Rhabdomyolysis - a phase IV clinical study of FDA data

Summary:

Rhabdomyolysis is found among people who take Isosorbide dinitrate, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Isosorbide dinitrate and have Rhabdomyolysis. It is created by eHealthMe based on reports of 11,798 people who have side effects when taking Isosorbide dinitrate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 07, 2022

11,798 people reported to have side effects when taking Isosorbide dinitrate.
Among them, 154 people (1.31%) have Rhabdomyolysis.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 11,898 Isosorbide dinitrate users for its effectiveness, alternative drugs and more.

What is Rhabdomyolysis?

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down) is found to be associated with 2,301 drugs and 1,857 conditions by eHealthMe.

Number of Isosorbide dinitrate and Rhabdomyolysis reports submitted per year:

Could Isosorbide dinitrate cause Rhabdomyolysis?

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide dinitrate and have Rhabdomyolysis?

Check whether Rhabdomyolysis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Rezigh, A. B., Armenia, E., Li, T., & Soesilo, I. , "Rifaximin as a rare cause of rhabdomyolysis in cirrhosis", Clinical case reports, 2018 Jan .
Moye, P. M., Manasen, S., & O’Brien, K., "Sulfamethoxazole-Trimethoprim-Induced Rhabdomyolysis in an Immunocompetent Patient: A Case Report", Medicine, 2014 Jan .

Related studies

How severe was Rhabdomyolysis and when was it recovered:

Rhabdomyolysis in Isosorbide dinitrate

Expand to all the drugs that have ingredients of isosorbide dinitrate:

Rhabdomyolysis and drugs with ingredients of isosorbide dinitrate (201 reports)

Alternative drugs to, pros and cons of Isosorbide dinitrate:

Isosorbide dinitrate (11,898 reports)

Common Isosorbide dinitrate side effects:

Hypotension (abnormally low blood pressure): 714 reports
Breathing difficulty: 689 reports
Chest pain: 680 reports
Weakness: 634 reports
Diarrhea: 579 reports
Fatigue (feeling of tiredness): 568 reports
Pneumonia: 546 reports

Browse all side effects of Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Rhabdomyolysis treatments and more:

Rhabdomyolysis (56,548 reports)

COVID vaccines that are related to Rhabdomyolysis:

Common drugs associated with Rhabdomyolysis:

All the drugs that are associated with Rhabdomyolysis:

Rhabdomyolysis (2,301 drugs)

Common conditions associated with Rhabdomyolysis:

High blood cholesterol: 5,093 reports
High blood pressure: 3,395 reports
Depression: 1,704 reports
Schizophrenia: 1,138 reports

All the conditions that are associated with Rhabdomyolysis:

Rhabdomyolysis (1,857 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate (the active ingredients of Isosorbide dinitrate) and Isosorbide dinitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.