Isosorbide dinitrate and Wax blockage - a phase IV clinical study of FDA data


Wax blockage is reported only by a few people who take Isosorbide Dinitrate.

The phase IV clinical study analyzes which people take Isosorbide dinitrate and have Wax blockage. It is created by eHealthMe based on reports of 11,798 people who have side effects while taking Isosorbide dinitrate from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 17, 2022

11,798 people reported to have side effects when taking Isosorbide dinitrate.
Among them, 3 people (0.03%) have Wax blockage.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 11,898 Isosorbide dinitrate users for its effectiveness, alternative drugs and more.

What is Wax blockage?

Wax blockage is found to be associated with 1,184 drugs and 875 conditions by eHealthMe.

Number of Isosorbide dinitrate and Wax blockage reports submitted per year:

Could Isosorbide dinitrate cause Wax blockage?

Gender of people who have Wax blockage when taking Isosorbide dinitrate *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Wax blockage when taking Isosorbide dinitrate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Isosorbide dinitrate *:

  1. Simvastatin: 3 people, 100.00%
  2. Glipizide: 2 people, 66.67%
  3. Lasix: 2 people, 66.67%
  4. Furosemide: 2 people, 66.67%
  5. Lopressor: 2 people, 66.67%
  6. Coumadin: 2 people, 66.67%
  7. Lipitor: 2 people, 66.67%
  8. Nitroglycerin: 2 people, 66.67%
  9. Digoxin: 2 people, 66.67%
  10. Aspirin: 2 people, 66.67%

Common side effects people have besides Wax blockage *:

  1. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 66.67%
  2. Disease Progression: 2 people, 66.67%
  3. Injury: 2 people, 66.67%
  4. Ill-Defined Disorder: 2 people, 66.67%
  5. Hypoglycemia (low blood sugar): 2 people, 66.67%
  6. Hyperhidrosis (abnormally increased sweating): 2 people, 66.67%
  7. Heart Rate Irregular: 2 people, 66.67%
  8. Hearing Loss: 2 people, 66.67%
  9. Weight Decreased: 2 people, 66.67%
  10. Fatigue (feeling of tiredness): 2 people, 66.67%

Common conditions people have *:

  1. Pulmonary Congestion (congestion in the lungs): 1 person, 33.33%
  2. Osteoporosis (bones weak and more likely to break): 1 person, 33.33%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 33.33%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide dinitrate and have Wax blockage?

Check whether Wax blockage is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Wax blockage and when was it recovered:

Expand to all the drugs that have ingredients of isosorbide dinitrate:

Alternative drugs to, pros and cons of Isosorbide dinitrate:

Common Isosorbide dinitrate side effects:

Browse all side effects of Isosorbide dinitrate:

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Wax blockage treatments and more:

COVID vaccines that are related to Wax blockage:

Common drugs associated with Wax blockage:

All the drugs that are associated with Wax blockage:

Common conditions associated with Wax blockage:

All the conditions that are associated with Wax blockage:

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate (the active ingredients of Isosorbide dinitrate) and Isosorbide dinitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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