Jakafi and Barrett's oesophagus - a phase IV clinical study of FDA data
Barrett's oesophagus is found among people who take Jakafi, especially for people who are male, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Jakafi and have Barrett's oesophagus. It is created by eHealthMe based on reports of 46,732 people who have side effects when taking Jakafi from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
46,732 people reported to have side effects when taking Jakafi.
Among them, 30 people (0.06%) have Barrett's oesophagus.
What is Jakafi?
Jakafi has active ingredients of ruxolitinib phosphate. It is often used in primary myelofibrosis. eHealthMe is studying from 46,798 Jakafi users for its effectiveness, alternative drugs and more.
What is Barrett's oesophagus?
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach) is found to be associated with 1,038 drugs and 560 conditions by eHealthMe.
Number of Jakafi and Barrett's oesophagus reports submitted per year:
Time on Jakafi when people have Barrett's oesophagus *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Barrett's oesophagus when taking Jakafi *:
- female: 6.67 %
- male: 93.33 %
Age of people who have Barrett's oesophagus when taking Jakafi *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
Common drugs people take besides Jakafi *:
- Xarelto: 24 people, 80.00%
- Klonopin: 21 people, 70.00%
- Desonate: 21 people, 70.00%
- Carafate: 21 people, 70.00%
- Clopidogrel: 21 people, 70.00%
- Vitamin D3: 20 people, 66.67%
- Vitamin D2: 19 people, 63.33%
- Hydrocodone: 17 people, 56.67%
- Marijuana: 14 people, 46.67%
- Hydrocodone Bitartrate And Acetaminophen: 11 people, 36.67%
Common side effects people have besides Barrett's oesophagus *:
- Malaise (a feeling of general discomfort or uneasiness): 23 people, 76.67%
- Thrombosis (formation of a blood clot inside a blood vessel): 23 people, 76.67%
- Fatigue (feeling of tiredness): 23 people, 76.67%
- Weight Increased: 23 people, 76.67%
- Nausea And Vomiting: 23 people, 76.67%
- Abdominal Discomfort: 23 people, 76.67%
- Diarrhea: 22 people, 73.33%
- Nosebleed (bleeding from nose): 22 people, 73.33%
- Feeling Abnormal: 22 people, 73.33%
- Headache (pain in head): 22 people, 73.33%
Common conditions people have *:
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 28 people, 93.33%
- Tooth Fracture: 15 people, 50.00%
- Joint Pain: 11 people, 36.67%
- Pain: 4 people, 13.33%
- Hypersensitivity: 3 people, 10.00%
- Varices Oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach): 2 people, 6.67%
- Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 2 people, 6.67%
- High Blood Pressure: 2 people, 6.67%
- Heart Rate Increased: 2 people, 6.67%
- Fever: 2 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Jakafi and have Barrett's oesophagus?Check whether Barrett's oesophagus is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
How severe was Barrett's oesophagus and when was it recovered:
Expand to all the drugs that have ingredients of ruxolitinib phosphate:
Alternative drugs to, pros and cons of Jakafi:
- Jakafi (46,798 reports)
Common Jakafi side effects:
Browse all side effects of Jakafi:a b c d e f g h i j k l m n o p q r s t u v w x y z
Barrett's oesophagus treatments and more:
- Barrett's oesophagus (7,655 reports)
COVID vaccines that are related to Barrett's oesophagus:
- Barrett's oesophagus in Moderna COVID Vaccine
- Barrett's oesophagus in Pfizer BioNTech Covid Vaccine
- Barrett's oesophagus in Johnson and Johnson Covid Vaccine
Common drugs associated with Barrett's oesophagus:
All the drugs that are associated with Barrett's oesophagus:
- Barrett's oesophagus (1,038 drugs)
Common conditions associated with Barrett's oesophagus:
All the conditions that are associated with Barrett's oesophagus:
- Barrett's oesophagus (560 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ruxolitinib phosphate (the active ingredients of Jakafi) and Jakafi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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