Jakafi and Cirrhosis alcoholic - a phase IV clinical study of FDA data

• Jakafi (40,564 reports)

• Abdominal discomfort: 812 reports
• Abdominal distension: 780 reports
• Abdominal fullness prematurely after meals: 114 reports
• Abdominal pain: 893 reports
• Abdominal pain upper: 592 reports
• Acne (skin problems that cause pimples): 175 reports
• Acute kidney failure: 229 reports
• Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 281 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 183 reports
• Alanine aminotransferase increased: 121 reports
• Anaemia (lack of blood): 2,803 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 726 reports
• Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 437 reports
• Arrhythmias (irregular heartbeat): 110 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 336 reports
• Arthropathy: 103 reports
• Ascites (accumulation of fluid in the abdominal cavity): 103 reports
• Aspartate aminotransferase increased: 132 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 311 reports
• Back pain: 892 reports
• Balance disorder: 449 reports
• Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 262 reports
• Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 148 reports
• Blood creatinine increased: 264 reports
• Blood disorder: 128 reports
• Blood glucose increased: 159 reports
• Blood iron decreased: 230 reports
• Blood lactate dehydrogenase increased: 188 reports
• Blood uric acid increased: 123 reports
• Bone marrow failure: 108 reports
• Bone pain: 715 reports
• Breathing difficulty: 2,067 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 376 reports
• Burning sensation: 229 reports
• Cardiac disorder: 208 reports
• Cardiac failure: 136 reports
• Cardiac failure congestive: 259 reports
• Cataract (clouding of the lens inside the eye): 105 reports
• Cellulitis (infection under the skin): 178 reports
• Chest pain: 555 reports
• Chills (felling of cold): 406 reports
• Chronic kidney disease: 122 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 116 reports
• Confusional state: 378 reports
• Constipation: 1,132 reports
• Cough: 972 reports
• Death: 3,604 reports
• Decreased activity: 282 reports
• Dehydration (dryness resulting from the removal of water): 418 reports
• Depressed mood: 183 reports
• Depression: 432 reports
• Diabetes: 109 reports
• Diarrhea: 2,214 reports
• Disease progression: 331 reports
• Disturbance in attention: 128 reports
• Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 122 reports
• Dizziness: 2,607 reports
• Drowsiness: 745 reports
• Drug ineffective: 741 reports
• Drug intolerance (drug sensitivity): 177 reports
• Dry mouth: 293 reports
• Dry skin: 305 reports
• Dyspnea exertional: 390 reports
• Eating disorder: 162 reports
• Energy increased: 147 reports
• Fainting (loss of consciousness and postural tone): 129 reports
• Fall: 1,339 reports
• Fatigue (feeling of tiredness): 5,129 reports
• Feeling cold: 179 reports
• Feeling hot: 180 reports
• Fever: 964 reports
• Flatulence (flatus expelled through the anus): 571 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 263 reports
• Full blood count decreased: 181 reports
• Gait disturbance: 556 reports
• Gastric disorder (disease of stomach): 112 reports
• Gastric ulcer (stomach ulcer): 109 reports
• Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection): 166 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 230 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 201 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 164 reports
• General physical health deterioration (weak health status): 162 reports
• Gout (uric acid crystals building up in the body): 389 reports
• Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 131 reports
• Haematocrit: 289 reports
• Haematocrit decreased: 621 reports
• Haematocrit increased: 314 reports
• Haematoma (collection of blood outside the blood vessels): 160 reports
• Haemoglobin decreased: 2,962 reports
• Haemoglobin increased: 207 reports
• Haemorrhage (bleeding): 467 reports
• Hair loss: 483 reports
• Headache (pain in head): 2,604 reports
• Head injury: 1,872 reports
• Heart attack: 203 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 229 reports
• Heart rate increased: 131 reports
• Hepatic enzyme increased: 142 reports
• Hepatomegaly (abnormal enlargement of the liver): 219 reports
• Herpes zoster: 659 reports
• High blood cholesterol: 441 reports
• High blood pressure: 703 reports
• Hip fracture: 111 reports
• Hoarseness or changing voice: 223 reports
• Hospitalisation: 192 reports
• Hot flush (sudden feelings of heat): 209 reports
• Hyperhidrosis (abnormally increased sweating): 413 reports
• Hyperkalemia (damage to or disease of the kidney): 287 reports
• Hypersensitivity: 226 reports
• Hypoaesthesia (reduced sense of touch or sensation): 428 reports
• Hypotension (abnormally low blood pressure): 419 reports
• Impaired healing: 218 reports
• Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone): 397 reports
• Indigestion: 329 reports
• Infection: 525 reports
• Influenza like illness: 166 reports
• Insomnia (sleeplessness): 770 reports
• Itching: 1,373 reports
• Joint injury: 111 reports
• Joint pain: 1,351 reports
• Joint swelling: 310 reports
• Kidney stones: 256 reports
• Leukaemia (blood or bone marrow cancer): 203 reports
• Leukocytosis (increased white blood cells): 170 reports
• Limb discomfort (discomfort in leg): 139 reports
• Limb injury: 204 reports
• Liver disorder (liver diseases): 137 reports
• Loss of consciousness: 168 reports
• Lung disorder (lung disease): 122 reports
• Malaise (a feeling of general discomfort or uneasiness): 1,623 reports
• Memory loss: 1,262 reports
• Migraine (headache): 230 reports
• Mobility decreased (ability to move is reduced): 205 reports
• Muscle aches (muscle pain): 544 reports
• Muscle spasms (muscle contraction): 911 reports
• Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 121 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 241 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 133 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 125 reports
• Nasopharyngitis (inflammation of the nasopharynx): 802 reports
• Nausea (feeling of having an urge to vomit): 1,753 reports
• Nausea and vomiting: 837 reports
• Neck pain: 167 reports
• Neoplasm malignant (cancer tumour): 135 reports
• Neuropathy peripheral (surface nerve damage): 307 reports
• Night sweats (sweating in night): 727 reports
• Nosebleed (bleeding from nose): 855 reports
• Oedema (fluid collection in tissue): 151 reports
• Oedema peripheral (superficial swelling): 429 reports
• Oral herpes (viral infection of mouth): 127 reports
• Oropharyngeal pain: 356 reports
• Pain: 1,328 reports
• Pain in extremity: 1,228 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 192 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 324 reports
• Peripheral swelling: 889 reports
• Pigmentation disorder (disturbances of human skin colour): 117 reports
• Platelet count increased: 1,429 reports
• Pleural effusion (water on the lungs): 132 reports
• Pneumonia: 1,578 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 267 reports
• Poor quality sleep: 161 reports
• Primary myelofibrosis (primary disorder of the bone marrow): 693 reports
• Pulmonary embolism (blockage of the main artery of the lung): 169 reports
• Rashes (redness): 1,303 reports
• Rash macular (small, flat red spots): 115 reports
• Rash pruritic (redness with itching): 120 reports
• Red blood cell count decreased: 961 reports
• Red blood cell count increased: 170 reports
• Renal disorder (kidney disease): 194 reports
• Renal impairment (severely reduced kidney function): 205 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 129 reports
• Rib fracture: 104 reports
• Second primary malignancy (after getting cure a cancer, a new cancer development): 103 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 321 reports
• Sinusitis (inflammation of sinus): 388 reports
• Skin cancer: 489 reports
• Skin discoloration: 326 reports
• Skin disorder (skin disease): 226 reports
• Skin exfoliation (removal of the oldest dead skin cells): 123 reports
• Skin ulcer: 235 reports
• Sleep disorder: 208 reports
• Speech impairment (adult) (inability to speak (adult)): 129 reports
• Spleen disorder (disease of spleen): 189 reports
• Splenomegaly (enlargement of spleen): 1,502 reports
• Squamous cell carcinoma (a cancer of a kind of epithelial cell): 249 reports
• Stomatitis (inflammation of mucous membrane of mouth): 447 reports
• Stress and anxiety: 611 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 274 reports
• Swallowing difficulty: 247 reports
• Swelling: 181 reports
• Taste - impaired: 128 reports
• The flu (the flu is caused by an influenza virus): 516 reports
• Therapeutic response unexpected: 544 reports
• Thrombocytopenia (decrease of platelets in blood): 3,182 reports
• Thrombocytosis: 126 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 375 reports
• Tinnitus (a ringing in the ears): 154 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 114 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 239 reports
• Tumor: 146 reports
• Upper respiratory tract infection: 191 reports
• Urinary tract infection: 865 reports
• Urination - painful: 114 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 122 reports
• Viral infection: 171 reports
• Vision blurred: 293 reports
• Visual impairment: 323 reports
• Weakness: 2,459 reports
• Weight decreased: 1,018 reports
• Weight increased: 2,127 reports
• White blood cell count decreased: 878 reports
• White blood cell count increased: 1,385 reports

• Cirrhosis alcoholic (749 reports)

All the drugs that are associated with Cirrhosis alcoholic:

• Cirrhosis alcoholic (363 drugs)

All the conditions that are associated with Cirrhosis alcoholic:

• Cirrhosis alcoholic (162 conditions)

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